Details for: ZFHX3

Gene ID: 463

Symbol: ZFHX3

Ensembl ID: ENSG00000140836

Description: zinc finger homeobox 3

Associated with

Other Information

Genular Protein ID: 2090749973

Symbol: ZFHX3_HUMAN

Name: Zinc finger homeobox protein 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7592926

Title: Cloning and characterization of an ATBF1 isoform that expresses in a neuronal differentiation-dependent manner.

PubMed ID: 7592926

DOI: 10.1074/jbc.270.45.26840

PubMed ID: 1719379

Title: A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers.

PubMed ID: 1719379

DOI: 10.1128/mcb.11.12.6041-6049.1991

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10493829

Title: Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

PubMed ID: 10493829

DOI: 10.1006/geno.1999.5927

PubMed ID: 11312261

Title: Positive and negative regulation of myogenic differentiation of C2C12 cells by isoforms of the multiple homeodomain zinc finger transcription factor ATBF1.

PubMed ID: 11312261

DOI: 10.1074/jbc.m010378200

PubMed ID: 14715251

Title: ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3.

PubMed ID: 14715251

DOI: 10.1016/j.bbrc.2003.12.054

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17330845

Title: Subcellular localization of ATBF1 regulates MUC5AC transcription in gastric cancer.

PubMed ID: 17330845

DOI: 10.1002/ijc.22654

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19597491

Title: A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.

PubMed ID: 19597491

DOI: 10.1038/ng.417

PubMed ID: 19597492

Title: Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.

PubMed ID: 19597492

DOI: 10.1038/ng.416

PubMed ID: 20599712

Title: Tumor suppressor, AT motif binding factor 1 (ATBF1), translocates to the nucleus with runt domain transcription factor 3 (RUNX3) in response to TGF-beta signal transduction.

PubMed ID: 20599712

DOI: 10.1016/j.bbrc.2010.06.090

PubMed ID: 20720010

Title: ATBF1 inhibits estrogen receptor (ER) function by selectively competing with AIB1 for binding to the ER in ER-positive breast cancer cells.

PubMed ID: 20720010

DOI: 10.1074/jbc.m110.128330

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22452784

Title: Oestrogen causes ATBF1 protein degradation through the oestrogen-responsive E3 ubiquitin ligase EFP.

PubMed ID: 22452784

DOI: 10.1042/bj20111890

PubMed ID: 23145062

Title: Human ALKBH4 interacts with proteins associated with transcription.

PubMed ID: 23145062

DOI: 10.1371/journal.pone.0049045

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25105025

Title: TGF-beta signaling cooperates with AT motif-binding factor-1 for repression of the alpha -fetoprotein promoter.

PubMed ID: 25105025

DOI: 10.1155/2014/970346

PubMed ID: 24651376

Title: Characterization of nuclear localization and SUMOylation of the ATBF1 transcription factor in epithelial cells.

PubMed ID: 24651376

DOI: 10.1371/journal.pone.0092746

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 3703
  • Mass: 404419
  • Checksum: 395F5D14A08112CB
  • Sequence:
  • MEGCDSPVVS GKDNGCGIPQ HQQWTELNST HLPDKPSSME QSTGESHGPL DSLRAPFNER 
    LAESTASAGP PSEPASKEVT CNECSASFAS LQTYMEHHCP SARPPPPLRE ESASDTGEEG 
    DEESDVENLA GEIVYQPDGS AYIVESLSQL TQGGGACGSG SGSGPLPSLF LNSLPGAGGK 
    QGDPSCAAPV YPQIINTFHI ASSFGKWFEG PDQAFPNTSA LAGLSPVLHS FRVFDVRHKS 
    NKDYLNSDGS AKSSCVSKDV PNNVDLSKFD GFVLYGKRKP ILMCFLCKLS FGYVRSFVTH 
    AVHDHRMTLS EDERKILSNK NISAIIQGIG KDKEPLVSFL EPKNKNFQHP LVSTANLIGP 
    GHSFYGKFSG IRMEGEEALP AGSAAGPEQP QAGLLTPSTL LNLGGLTSSV LKTPITSVPL 
    GPLASSPTKS SEGKDSGAAE GEKQEVGDGD CFSEKVEPAE EEAEEEEEEE EAEEEEEEEE 
    EEEEEEEDEG CKGLFPSELD EELEDRPHEE PGAAAGSSSK KDLALSNQSI SNSPLMPNVL 
    QTLSRGTAST SSNSASSFVV FDGANRRNRL SFNSEGVRAN VAEGGRRLDF ADESANKDNA 
    TAPEPNESTE GDDGGFVPHH QHAGSLCELG VGECPSGSGV ECPKCDTVLG SSRSLGGHMT 
    MMHSRNSCKT LKCPKCNWHY KYQQTLEAHM KEKHPEPGGS CVYCKSGQPH PRLARGESYT 
    CGYKPFRCEV CNYSTTTKGN LSIHMQSDKH LNNMQNLQNG GGEQVFSHTA GAAAAAVAAA 
    AAAANISSSC GAPSPTKPKT KPTWRCEVCD YETNVARNLR IHMTSEKHMH NMMLLQQNMT 
    QIQHNRHLGL GSLPSPAEAE LYQYYLAQNM NLPNLKMDSA ASDAQFMMSG FQLDPAGPMA 
    AMTPALVGGE IPLDMRLGGG QLVSEELMNL GESFIQTNDP SLKLFQCAVC NKFTTDNLDM 
    LGLHMNVERS LSEDEWKAVM GDSYQCKLCR YNTQLKANFQ LHCKTDKHVQ KYQLVAHIKE 
    GGKANEWRLK CVAIGNPVHL KCNACDYYTN SLEKLRLHTV NSRHEASLKL YKHLQQHESG 
    VEGESCYYHC VLCNYSTKAK LNLIQHVRSM KHQRSESLRK LQRLQKGLPE EDEDLGQIFT 
    IRRCPSTDPE EAIEDVEGPS ETAADPEELA KDQEGGASSS QAEKELTDSP ATSKRISFPG 
    SSESPLSSKR PKTAEEIKPE QMYQCPYCKY SNADVNRLRV HAMTQHSVQP MLRCPLCQDM 
    LNNKIHLQLH LTHLHSVAPD CVEKLIMTVT TPEMVMPSSM FLPAAVPDRD GNSNLEEAGK 
    QPETSEDLGK NILPSASTEQ SGDLKPSPAD PGSVREDSGF ICWKKGCNQV FKTSAALQTH 
    FNEVHAKRPQ LPVSDRHVYK YRCNQCSLAF KTIEKLQLHS QYHVIRAATM CCLCQRSFRT 
    FQALKKHLET SHLELSEADI QQLYGGLLAN GDLLAMGDPT LAEDHTIIVE EDKEEESDLE 
    DKQSPTGSDS GSVQEDSGSE PKRALPFRKG PNFTMEKFLD PSRPYKCTVC KESFTQKNIL 
    LVHYNSVSHL HKLKRALQES ATGQPEPTSS PDNKPFKCNT CNVAYSQSST LEIHMRSVLH 
    QTKARAAKLE AASGSSNGTG NSSSISLSSS TPSPVSTSGS NTFTTSNPSS AGIAPSSNLL 
    SQVPTESVGM PPLGNPIGAN IASPSEPKEA NRKKLADMIA SRQQQQQQQQ QQQQQQQQQQ 
    QAQTLAQAQA QVQAHLQQEL QQQAALIQSQ LFNPTLLPHF PMTTETLLQL QQQQHLLFPF 
    YIPSAEFQLN PEVSLPVTSG ALTLTGTGPG LLEDLKAQVQ VPQQSHQQIL PQQQQNQLSI 
    AQSHSALLQP SQHPEKKNKL VIKEKEKESQ RERDSAEGGE GNTGPKETLP DALKAKEKKE 
    LAPGGGSEPS MLPPRIASDA RGNATKALLE NFGFELVIQY NENKQKVQKK NGKTDQGENL 
    EKLECDSCGK LFSNILILKS HQEHVHQNYF PFKQLERFAK QYRDHYDKLY PLRPQTPEPP 
    PPPPPPPPPP LPAAPPQPAS TPAIPASAPP ITSPTIAPAQ PSVPLTQLSM PMELPIFSPL 
    MMQTMPLQTL PAQLPPQLGP VEPLPADLAQ LYQHQLNPTL LQQQNKRPRT RITDDQLRVL 
    RQYFDINNSP SEEQIKEMAD KSGLPQKVIK HWFRNTLFKE RQRNKDSPYN FSNPPITSLE 
    ELKIDSRPPS PEPPKQEYWG SKRSSRTRFT DYQLRVLQDF FDANAYPKDD EFEQLSNLLN 
    LPTRVIVVWF QNARQKARKN YENQGEGKDG ERRELTNDRY IRTSNLNYQC KKCSLVFQRI 
    FDLIKHQKKL CYKDEDEEGQ DDSQNEDSMD AMEILTPTSS SCSTPMPSQA YSAPAPSANN 
    TASSAFLQLT AEAEELATFN SKTEAGDEKP KLAEAPSAQP NQTQEKQGQP KPELQQQEQP 
    EQKTNTPQQK LPQLVSLPSL PQPPPQAPPP QCPLPQSSPS PSQLSHLPLK PLHTSTPQQL 
    ANLPPQLIPY QCDQCKLAFP SFEHWQEHQQ LHFLSAQNQF IHPQFLDRSL DMPFMLFDPS 
    NPLLASQLLS GAIPQIPASS ATSPSTPTST MNTLKRKLEE KASASPGEND SGTGGEEPQR 
    DKRLRTTITP EQLEILYQKY LLDSNPTRKM LDHIAHEVGL KKRVVQVWFQ NTRARERKGQ 
    FRAVGPAQAH RRCPFCRALF KAKTALEAHI RSRHWHEAKR AGYNLTLSAM LLDCDGGLQM 
    KGDIFDGTSF SHLPPSSSDG QGVPLSPVSK TMELSPRTLL SPSSIKVEGI EDFESPSMSS 
    VNLNFDQTKL DNDDCSSVNT AITDTTTGDE GNADNDSATG IATETKSSSA PNEGLTKAAM 
    MAMSEYEDRL SSGLVSPAPS FYSKEYDNEG TVDYSETSSL ADPCSPSPGA SGSAGKSGDS 
    GDRPGQKRFR TQMTNLQLKV LKSCFNDYRT PTMLECEVLG NDIGLPKRVV QVWFQNARAK 
    EKKSKLSMAK HFGINQTSYE GPKTECTLCG IKYSARLSVR DHIFSQQHIS KVKDTIGSQL 
    DKEKEYFDPA TVRQLMAQQE LDRIKKANEV LGLAAQQQGM FDNTPLQALN LPTAYPALQG 
    IPPVLLPGLN SPSLPGFTPS NTALTSPKPN LMGLPSTTVP SPGLPTSGLP NKPSSASLSS 
    PTPAQATMAM GPQQPPQQQQ QQQQPQVQQP PPPPAAQPPP TPQLPLQQQQ QRKDKDSEKV 
    KEKEKAHKGK GEPLPVPKKE KGEAPTATAA TISAPLPTME YAVDPAQLQA LQAALTSDPT 
    ALLTSQFLPY FVPGFSPYYA PQIPGALQSG YLQPMYGMEG LFPYSPALSQ ALMGLSPGSL 
    LQQYQQYQQS LQEAIQQQQQ RQLQQQQQQK VQQQQPKASQ TPVPPGAPSP DKDPAKESPK 
    PEEQKNTPRE VSPLLPKLPE EPEAESKSAD SLYDPFIVPK VQYKLVCRKC QAGFSDEEAA 
    RSHLKSLCFF GQSVVNLQEM VLHVPTGGGG GGSGGGGGGG GGGGGGGSYH CLACESALCG 
    EEALSQHLES ALHKHRTITR AARNAKEHPS LLPHSACFPD PSTASTSQSA AHSNDSPPPP 
    SAAAPSSASP HASRKSWPQV VSRASAAKPP SFPPLSSSST VTSSSCSTSG VQPSMPTDDY 
    SEESDTDLSQ KSDGPASPVE GPKDPSCPKD SGLTSVGTDT FRL

Genular Protein ID: 1744688580

Symbol: Q8N2Y6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 886
  • Mass: 98584
  • Checksum: D53825266E5B7EC2
  • Sequence:
  • MRLGGGQLVS EELMNLGESF IQTNDPSLKL FQCAVCNKFT TDNLDMLGLH MNVERSLSED 
    EWKAVMGDSY QCKLCRYNTQ LKANFQLHCK TDKHVQKYQL VAHIKEGGKA NEWRLKCVAI 
    GNPVHLKCNA CDYYTNSLEK LRLHTVNSRH EASLKLYKHL QQHESGVEGE SCYYHCVLCN 
    YSTKAKLNLI QHVRSMKHQR SESLRKLQRL QKGLPEEDED LGQIFTIRRC PSTDPEEAIE 
    DVEGPSETAA DPEELAKDQE GGASSSQAEK ELTDSPATSK RISFPGSSES PLSSKRPKTA 
    EEIKPEQMYQ CPYCKYSNAD VNRLRVHAMT QHSVQPMLRC PLCQDMLNNK IHLQLHLTHL 
    HSVAPDCVEK LIMTVTTPEM VMPSSMFLPA AVPDRDGNSN LEEAGKQPET SEDLGKNILP 
    SASTEQSGDL KPSPADPGSV REDSGFICWK KGCNQVFKTS AALQTHFNEV HAKRPQLPVS 
    DRHVYKYRCN QCSLAFKTIE KLQLHSQYHV IRAATMCCLC QRSFRTFQAL KKHLETSHLE 
    LSEADIQQLY GGLLANGDLL AMGDPTLAED HTIIVEEDKE EESDLEDKQS PTGSDSGSVQ 
    EDSGSEPKRA LPFRKGPNFT MEKFLDPSRP YKCTVCKESF TQKNILLVHY NSVSHLHKLK 
    RALQESATGQ PEPTSSPDNK PFKCNTCNVA YSQSSTLEIH MRSVLHQTKA RAAKLEAASG 
    SSNGTGNSSS ISLSSSTPSP VSTSGSNTFT TSNPSSAGIA PSSNLLSQVP TESVGMPPLG 
    NPIGANIASP SEPKEANRKK LADMIASRQQ QQQQQQQQQQ QQQQQQQAQT LAQAQAQVQA 
    HLQQELQQQA ALIQSQLFNP TLLPHFPMTT ETLLQLQQQQ HPLYPL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.