ATF1 | ENSG00000123268 | NCBI 466

Details for: ATF1

Gene ID: 466

Symbol: ATF1

Ensembl ID: ENSG00000123268

Description: activating transcription factor 1

Associated with

Creb phosphorylation
(R-HSA-199920)
Cytokine signaling in immune system
(R-HSA-1280215)
Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Interleukin-17 signaling
(R-HSA-448424)
Map kinase activation
(R-HSA-450294)
Mapk targets/ nuclear events mediated by map kinases
(R-HSA-450282)
Myd88 cascade initiated on plasma membrane
(R-HSA-975871)
Myd88 dependent cascade initiated on endosome
(R-HSA-975155)
Myd88-independent tlr4 cascade
(R-HSA-166166)
Myd88:mal(tirap) cascade initiated on plasma membrane
(R-HSA-166058)
Ngf-stimulated transcription
(R-HSA-9031628)
Nuclear events (kinase and transcription factor activation)
(R-HSA-198725)
Signaling by interleukins
(R-HSA-449147)
Signaling by ntrk1 (trka)
(R-HSA-187037)
Signaling by ntrks
(R-HSA-166520)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signal transduction
(R-HSA-162582)
Toll-like receptor cascades
(R-HSA-168898)
Toll like receptor 2 (tlr2) cascade
(R-HSA-181438)
Toll like receptor 3 (tlr3) cascade
(R-HSA-168164)
Toll like receptor 4 (tlr4) cascade
(R-HSA-166016)
Toll like receptor 5 (tlr5) cascade
(R-HSA-168176)
Toll like receptor 7/8 (tlr7/8) cascade
(R-HSA-168181)
Toll like receptor 9 (tlr9) cascade
(R-HSA-168138)
Toll like receptor 10 (tlr10) cascade
(R-HSA-168142)
Toll like receptor tlr1:tlr2 cascade
(R-HSA-168179)
Toll like receptor tlr6:tlr2 cascade
(R-HSA-168188)
Traf6 mediated induction of nfkb and map kinases upon tlr7/8 or 9 activation
(R-HSA-975138)
Trif(ticam1)-mediated tlr4 signaling
(R-HSA-937061)
Atf1-atf4 transcription factor complex
(GO:1990590)
Atf4-creb1 transcription factor complex
(GO:1990589)
Camp-mediated signaling
(GO:0019933)
Chromatin
(GO:0000785)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Identical protein binding
(GO:0042802)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of dna replication
(GO:0045740)
Positive regulation of neuron projection development
(GO:0010976)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-containing complex assembly
(GO:0065003)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to cobalt ion
(GO:0032025)
Response to purine-containing compound
(GO:0014074)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)

Other Information

Proteins

Cyclic AMP-dependent transcription factor ATF-1

Genular Protein ID: 3635521474

Symbol: ATF1_HUMAN

Name: Cyclic AMP-dependent transcription factor ATF-1

UniProtKB Accession Codes:

P18846 B4DRF9 P25168 Q9H4A8

Database IDs:

Citations:

PubMed ID: 2196176

Title: Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain.

PubMed ID: 2196176

DOI: 10.1002/j.1460-2075.1990.tb07434.x

PubMed ID: 1655749

Title: The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A.

PubMed ID: 1655749

DOI: 10.1016/s0021-9258(18)55078-x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2516827

Title: Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

PubMed ID: 2516827

DOI: 10.1101/gad.3.12b.2083

PubMed ID: 11063792

Title: Genetic characterization of angiomatoid fibrous histiocytoma identifies fusion of the FUS and ATF-1 genes induced by a chromosomal translocation involving bands 12q13 and 16p11.

PubMed ID: 11063792

DOI: 10.1016/s0165-4608(00)00237-5

PubMed ID: 8621702

Title: Regulation of activating transcription factor-1 and the cAMP response element-binding protein by Ca2+/calmodulin-dependent protein kinases type I, II, and IV.

PubMed ID: 8621702

DOI: 10.1074/jbc.271.6.3066

PubMed ID: 15884099

Title: Fusion of the EWSR1 and ATF1 genes without expression of the MITF-M transcript in angiomatoid fibrous histiocytoma.

PubMed ID: 15884099

DOI: 10.1002/gcc.20201

PubMed ID: 18794154

Title: Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation.

PubMed ID: 18794154

DOI: 10.1158/0008-5472.can-08-1137

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20980392

Title: Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress.

PubMed ID: 20980392

DOI: 10.1242/jcs.073627

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 29983246

Title: The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress.

PubMed ID: 29983246

DOI: 10.1016/j.cmet.2018.06.008

Sequence Information:

Length: 271
Mass: 29233
Checksum: BAFECBFFB244FCED
Sequence:

MEDSHKSTTS ETAPQPGSAV QGAHISHIAQ QVSSLSESEE SQDSSDSIGS SQKAHGILAR 
RPSYRKILKD LSSEDTRGRK GDGENSGVSA AVTSMSVPTP IYQTSSGQYI AIAPNGALQL 
ASPGTDGVQG LQTLTMTNSG STQQGTTILQ YAQTSDGQQI LVPSNQVVVQ TASGDMQTYQ 
IRTTPSATSL PQTVVMTSPV TLTSQTTKTD DPQLKREIRL MKNREAAREC RRKKKEYVKC 
LENRVAVLEN QNKTLIEELK TLKDLYSNKS V

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ATF1

Associated with

Other Information

Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain. PubMed ID: 2196176

The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A. PubMed ID: 1655749

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The finished DNA sequence of human chromosome 12. PubMed ID: 16541075

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. PubMed ID: 2516827

Genetic characterization of angiomatoid fibrous histiocytoma identifies fusion of the FUS and ATF-1 genes induced by a chromosomal translocation involving bands 12q13 and 16p11. PubMed ID: 11063792

Regulation of activating transcription factor-1 and the cAMP response element-binding protein by Ca2+/calmodulin-dependent protein kinases type I, II, and IV. PubMed ID: 8621702

Fusion of the EWSR1 and ATF1 genes without expression of the MITF-M transcript in angiomatoid fibrous histiocytoma. PubMed ID: 15884099

Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation. PubMed ID: 18794154

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress. PubMed ID: 20980392

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress. PubMed ID: 29983246