Details for: ATF3

Gene ID: 467

Symbol: ATF3

Ensembl ID: ENSG00000162772

Description: activating transcription factor 3

Associated with

  • Atf4 activates genes in response to endoplasmic reticulum stress
    (R-HSA-380994)
  • Cellular responses to stimuli
    (R-HSA-8953897)
  • Cellular responses to stress
    (R-HSA-2262752)
  • Cellular response to starvation
    (R-HSA-9711097)
  • Perk regulates gene expression
    (R-HSA-381042)
  • Response of eif2ak1 (hri) to heme deficiency
    (R-HSA-9648895)
  • Response of eif2ak4 (gcn2) to amino acid deficiency
    (R-HSA-9633012)
  • Unfolded protein response (upr)
    (R-HSA-381119)
  • Cellular response to amino acid starvation
    (GO:0034198)
  • Chop-atf3 complex
    (GO:1990622)
  • Chromatin
    (GO:0000785)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Endoplasmic reticulum unfolded protein response
    (GO:0030968)
  • Gluconeogenesis
    (GO:0006094)
  • Identical protein binding
    (GO:0042802)
  • Negative regulation of erk1 and erk2 cascade
    (GO:0070373)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleolus
    (GO:0005730)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of trail-activated apoptotic signaling pathway
    (GO:1903984)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Protein heterodimerization activity
    (GO:0046982)
  • Protein homodimerization activity
    (GO:0042803)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Response to endoplasmic reticulum stress
    (GO:0034976)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulator complex
    (GO:0090575)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Skeletal muscle cell differentiation
    (GO:0035914)
  • Transcription cis-regulatory region binding
    (GO:0000976)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 360.8597
    Cell Significance Index: -56.1300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 211.0838
    Cell Significance Index: -53.5400
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 136.4494
    Cell Significance Index: -56.2100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 122.7435
    Cell Significance Index: -57.9500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 118.1395
    Cell Significance Index: -48.0000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 108.6151
    Cell Significance Index: -55.8700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 85.5709
    Cell Significance Index: -57.4200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 50.9168
    Cell Significance Index: -48.6100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 45.6910
    Cell Significance Index: -56.3400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 20.9679
    Cell Significance Index: -56.1700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.2329
    Cell Significance Index: -52.9300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 14.1914
    Cell Significance Index: -56.0000
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 12.8140
    Cell Significance Index: 78.8600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 7.7541
    Cell Significance Index: 137.0300
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 7.1899
    Cell Significance Index: 27.5300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.8537
    Cell Significance Index: -15.0000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 5.5167
    Cell Significance Index: 158.1400
  • Cell Name: peg cell (CL4033014)
    Fold Change: 5.2538
    Cell Significance Index: 121.3800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 5.0478
    Cell Significance Index: 68.8700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 4.5560
    Cell Significance Index: 124.0100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 3.6725
    Cell Significance Index: 273.7100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 3.5200
    Cell Significance Index: 164.1200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 3.1969
    Cell Significance Index: 166.0700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 3.0152
    Cell Significance Index: 141.7100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.7351
    Cell Significance Index: 353.3600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 2.5579
    Cell Significance Index: 1130.9200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 2.4466
    Cell Significance Index: 36.6600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 2.0788
    Cell Significance Index: 147.0200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.0610
    Cell Significance Index: 59.3800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 2.0355
    Cell Significance Index: 232.3500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.7580
    Cell Significance Index: 91.5700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.4028
    Cell Significance Index: 63.5900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.2838
    Cell Significance Index: 157.8500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.1671
    Cell Significance Index: 149.6200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.1073
    Cell Significance Index: 604.7200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0777
    Cell Significance Index: 205.0900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.0576
    Cell Significance Index: 28.2400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7176
    Cell Significance Index: 70.9900
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 0.6887
    Cell Significance Index: 3.1800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6757
    Cell Significance Index: 121.8000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6444
    Cell Significance Index: 581.8300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.4977
    Cell Significance Index: 17.4900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.4849
    Cell Significance Index: 4.4700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.3398
    Cell Significance Index: 6.2800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2863
    Cell Significance Index: 8.0000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2834
    Cell Significance Index: 38.9200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2552
    Cell Significance Index: 41.5100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2262
    Cell Significance Index: 38.6300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1666
    Cell Significance Index: 11.5200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1336
    Cell Significance Index: 8.6200
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: 0.1326
    Cell Significance Index: 2.7700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1079
    Cell Significance Index: 3.7500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1018
    Cell Significance Index: 20.2000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0532
    Cell Significance Index: 24.1400
  • Cell Name: salivary gland glandular cell (CL1001596)
    Fold Change: 0.0476
    Cell Significance Index: 0.2700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0367
    Cell Significance Index: 3.7500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0086
    Cell Significance Index: 6.3100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0057
    Cell Significance Index: 0.6200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0019
    Cell Significance Index: -1.4300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0048
    Cell Significance Index: -9.0700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0303
    Cell Significance Index: -22.9600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0309
    Cell Significance Index: -47.6400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0319
    Cell Significance Index: -43.4100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0324
    Cell Significance Index: -59.7900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0494
    Cell Significance Index: -30.8500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0578
    Cell Significance Index: -36.7100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0672
    Cell Significance Index: -37.9100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0674
    Cell Significance Index: -46.6100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1223
    Cell Significance Index: -14.0100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.1317
    Cell Significance Index: -47.2600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1369
    Cell Significance Index: -39.4000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1571
    Cell Significance Index: -33.0900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1639
    Cell Significance Index: -0.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.1696
    Cell Significance Index: -34.0200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1966
    Cell Significance Index: -15.0900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2023
    Cell Significance Index: -1.6500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2663
    Cell Significance Index: -31.0400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.3046
    Cell Significance Index: -3.4600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3188
    Cell Significance Index: -46.3400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3939
    Cell Significance Index: -12.6200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.4148
    Cell Significance Index: -24.9000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.4472
    Cell Significance Index: -52.7400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4516
    Cell Significance Index: -11.2900
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.4748
    Cell Significance Index: -2.9500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5052
    Cell Significance Index: -52.6000
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.5140
    Cell Significance Index: -5.9800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5445
    Cell Significance Index: -28.5900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5636
    Cell Significance Index: -14.8200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.6116
    Cell Significance Index: -13.2500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.6182
    Cell Significance Index: -12.9400
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.6430
    Cell Significance Index: -8.2800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6549
    Cell Significance Index: -51.8700
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: -0.7001
    Cell Significance Index: -5.7900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.7034
    Cell Significance Index: -18.8200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.7049
    Cell Significance Index: -47.4000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7262
    Cell Significance Index: -44.5200
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.7655
    Cell Significance Index: -6.4300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.8246
    Cell Significance Index: -33.7900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.8332
    Cell Significance Index: -51.2100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.9603
    Cell Significance Index: -23.4300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** ATF3 is a member of the ATF/CREB family of transcription factors, which are known for their ability to regulate gene expression in response to a wide range of stimuli. ATF3 is characterized by its ability to bind to specific DNA sequences and regulate the expression of target genes involved in cell survival, proliferation, and differentiation. Its expression is regulated by various signaling pathways, including the ER stress pathway, the amino acid starvation pathway, and the negative regulation of the ERK1/2 cascade. **Pathways and Functions** ATF3 is involved in several key pathways, including: 1. **Endoplasmic Reticulum Unfolded Protein Response (UPR)**: ATF3 is activated in response to ER stress, which is a common feature of various diseases, including cancer, neurodegenerative disorders, and metabolic disorders. The UPR pathway is activated in response to ER stress, and ATF3 plays a crucial role in regulating the expression of target genes involved in cell survival and proliferation. 2. **Cellular Responses to Stimuli**: ATF3 is involved in regulating cellular responses to various forms of stimuli, including ER stress, amino acid starvation, and starvation. Its expression is regulated by various signaling pathways, including the ER stress pathway, the amino acid starvation pathway, and the negative regulation of the ERK1/2 cascade. 3. **Gene Expression Regulation**: ATF3 is a transcription factor that regulates the expression of target genes involved in cell survival, proliferation, and differentiation. Its expression is regulated by specific DNA sequences, and it is involved in regulating the expression of genes involved in various cellular processes, including gluconeogenesis, protein synthesis, and cell cycle progression. 4. **Cell Differentiation**: ATF3 is involved in regulating cell differentiation, particularly in the context of skeletal muscle cell differentiation. Its expression is regulated by specific DNA sequences, and it is involved in regulating the expression of genes involved in muscle cell differentiation. **Clinical Significance** ATF3 has been implicated in various diseases, including: 1. **Cancer**: ATF3 is overexpressed in various types of cancer, including breast, lung, and colon cancer. Its expression is regulated by specific DNA sequences, and it is involved in regulating the expression of genes involved in cell proliferation and survival. 2. **Neurodegenerative Disorders**: ATF3 is involved in regulating cellular responses to ER stress, which is a common feature of various neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. 3. **Metabolic Disorders**: ATF3 is involved in regulating cellular responses to ER stress, which is a common feature of various metabolic disorders, including type 2 diabetes and metabolic syndrome. 4. **Skeletal Muscle Diseases**: ATF3 is involved in regulating skeletal muscle cell differentiation and is implicated in various skeletal muscle diseases, including muscular dystrophy and myopathy. In conclusion, ATF3 is a multifunctional transcription factor that plays a crucial role in regulating cellular responses to various forms of stress, including ER stress, amino acid starvation, and starvation. Its expression is regulated by specific DNA sequences, and it is involved in regulating the expression of target genes involved in cell survival, proliferation, and differentiation. Its clinical significance is evident in its involvement in various diseases, including cancer, neurodegenerative disorders, metabolic disorders, and skeletal muscle diseases. Further studies are needed to fully elucidate the mechanisms of ATF3 and its role in various diseases.

Genular Protein ID: 2353326803

Symbol: ATF3_HUMAN

Name: Activating transcription factor 3

UniProtKB Accession Codes:

P18847 Q5VTZ2 Q6ICQ9 Q7Z566 Q8WYM6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CORUM 1 CPTAC 1 CTD 1 ChiTaRS 1 ComplexPortal 18 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 18 Ensembl 6 ExpressionAtlas 1 GO 29 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 3 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 3 RefSeq 8 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7515060

Title: ATF3 and ATF3 delta Zip. Transcriptional repression versus activation by alternatively spliced isoforms.

PubMed ID: 7515060

DOI: 10.1016/s0021-9258(17)40754-x

PubMed ID: 12034827

Title: An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli.

PubMed ID: 12034827

DOI: 10.1093/nar/30.11.2398

PubMed ID: 12881527

Title: Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple activating transcription factor-3 mRNA species that, when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter.

PubMed ID: 12881527

DOI: 10.1074/jbc.m304574200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2516827

Title: Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

PubMed ID: 2516827

DOI: 10.1101/gad.3.12b.2083

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 25865756

Title: The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60.

PubMed ID: 25865756

DOI: 10.1038/ncomms7752

PubMed ID: 29463886

Title: A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech development.

PubMed ID: 29463886

DOI: 10.1038/s41380-018-0020-x

Sequence Information:

  • Length: 181
  • Mass: 20576
  • Checksum: EC5D8F065EEE2D9C
  • Sequence:
    • MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS 
ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK 
LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ 
S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.