Details for: RERE
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 829.9837
Cell Significance Index: -129.1000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 495.4594
Cell Significance Index: -125.6700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 272.4292
Cell Significance Index: -128.6200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 257.1278
Cell Significance Index: -104.4600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 235.9904
Cell Significance Index: -121.3900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 109.6526
Cell Significance Index: -104.6900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 105.2187
Cell Significance Index: -129.7300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 46.3817
Cell Significance Index: -124.2500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 40.4906
Cell Significance Index: -124.3700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 35.8770
Cell Significance Index: -78.5200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 33.0305
Cell Significance Index: -130.3400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 10.3543
Cell Significance Index: 581.0300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 7.0149
Cell Significance Index: 431.1700 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 6.7412
Cell Significance Index: 59.8400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 6.6890
Cell Significance Index: 160.4200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 4.6396
Cell Significance Index: 1664.1400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 4.3200
Cell Significance Index: 331.5100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 4.0678
Cell Significance Index: 807.2600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 3.7128
Cell Significance Index: 103.7600 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 3.4329
Cell Significance Index: 21.1800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 3.2991
Cell Significance Index: 2281.8000 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 3.1300
Cell Significance Index: 76.3700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 3.1197
Cell Significance Index: 625.8000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 2.8524
Cell Significance Index: 60.9700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.2688
Cell Significance Index: 58.3200 - Cell Name: preadipocyte (CL0002334)
Fold Change: 2.2642
Cell Significance Index: 44.1900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.8485
Cell Significance Index: 81.7700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.7710
Cell Significance Index: 119.0800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.7504
Cell Significance Index: 79.3400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.7347
Cell Significance Index: 312.7200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.7171
Cell Significance Index: 3233.1700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.6082
Cell Significance Index: 60.9000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.4083
Cell Significance Index: 173.1600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.2690
Cell Significance Index: 805.9500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.2181
Cell Significance Index: 1875.2200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.1094
Cell Significance Index: 2045.9500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.0959
Cell Significance Index: 119.2100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.9116
Cell Significance Index: 26.2700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.9010
Cell Significance Index: 408.9200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.8981
Cell Significance Index: 1221.1700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.8695
Cell Significance Index: 14.9000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.6897
Cell Significance Index: 376.6700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.6633
Cell Significance Index: 14.3700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.6195
Cell Significance Index: 17.6800 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 0.6115
Cell Significance Index: 6.3700 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.5350
Cell Significance Index: 7.7000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3597
Cell Significance Index: 68.4600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.3440
Cell Significance Index: 47.2400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2866
Cell Significance Index: 126.7000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2783
Cell Significance Index: 45.2600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1787
Cell Significance Index: 6.2800 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.1770
Cell Significance Index: 2.1100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1121
Cell Significance Index: 101.2000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0968
Cell Significance Index: 5.0300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.0460
Cell Significance Index: 4.7900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0079
Cell Significance Index: 0.2100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0122
Cell Significance Index: -0.6400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0304
Cell Significance Index: -3.0100 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.0432
Cell Significance Index: -0.6200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0485
Cell Significance Index: -2.2800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0779
Cell Significance Index: -1.1500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0785
Cell Significance Index: -57.5500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0856
Cell Significance Index: -4.4600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0947
Cell Significance Index: -70.1600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1200
Cell Significance Index: -3.2100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.1499
Cell Significance Index: -113.4500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1526
Cell Significance Index: -95.3300 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1706
Cell Significance Index: -21.8700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1779
Cell Significance Index: -100.3000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1971
Cell Significance Index: -9.1900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.2174
Cell Significance Index: -37.1200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3273
Cell Significance Index: -47.5800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3921
Cell Significance Index: -82.5800 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.3950
Cell Significance Index: -6.0100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.3971
Cell Significance Index: -114.2700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.4219
Cell Significance Index: -49.7500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.5060
Cell Significance Index: -4.6600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.5871
Cell Significance Index: -59.9700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.6997
Cell Significance Index: -52.1500 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.7321
Cell Significance Index: -94.5900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.7611
Cell Significance Index: -88.7000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.7833
Cell Significance Index: -49.3700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.8133
Cell Significance Index: -93.1800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -1.0901
Cell Significance Index: -70.3300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -1.0907
Cell Significance Index: -6.5900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -1.1118
Cell Significance Index: -126.9100 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -1.1821
Cell Significance Index: -7.2700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -1.2099
Cell Significance Index: -85.5700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.3596
Cell Significance Index: -107.6800 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -1.3641
Cell Significance Index: -17.0100 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -1.4430
Cell Significance Index: -18.1700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -1.6656
Cell Significance Index: -36.4700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.7028
Cell Significance Index: -104.4000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -1.7224
Cell Significance Index: -23.5000 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -1.7613
Cell Significance Index: -22.2300 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -1.7868
Cell Significance Index: -35.3300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -1.9246
Cell Significance Index: -66.8800 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -1.9741
Cell Significance Index: -29.5800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -1.9836
Cell Significance Index: -56.8600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -2.0208
Cell Significance Index: -66.1600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3965439129
Symbol: RERE_HUMAN
Name: Arginine-glutamic acid dipeptide repeats protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10814707
Title: Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine.
PubMed ID: 10814707
DOI: 10.1093/hmg/9.9.1433
PubMed ID: 11331249
Title: Human RERE is localized to nuclear promyelocytic leukemia oncogenic domains and enhances apoptosis.
PubMed ID: 11331249
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 9455484
Title: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.
PubMed ID: 9455484
PubMed ID: 10729226
Title: Identification and characterization of novel genes located at the t(1;15)(p36.2;q24) translocation breakpoint in the neuroblastoma cell line NGP.
PubMed ID: 10729226
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19131340
Title: Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells.
PubMed ID: 19131340
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 27087320
Title: De novo mutations of RERE cause a genetic syndrome with features that overlap those associated with proximal 1p36 deletions.
PubMed ID: 27087320
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 1566
- Mass: 172424
- Checksum: ECA4A22026E3E96F
- Sequence:
MTADKDKDKD KEKDRDRDRD REREKRDKAR ESENSRPRRS CTLEGGAKNY AESDHSEDED NDNNSATAEE STKKNKKKPP KKKSRYERTD TGEITSYITE DDVVYRPGDC VYIESRRPNT PYFICSIQDF KLVHNSQACC RSPTPALCDP PACSLPVASQ PPQHLSEAGR GPVGSKRDHL LMNVKWYYRQ SEVPDSVYQH LVQDRHNEND SGRELVITDP VIKNRELFIS DYVDTYHAAA LRGKCNISHF SDIFAAREFK ARVDSFFYIL GYNPETRRLN STQGEIRVGP SHQAKLPDLQ PFPSPDGDTV TQHEELVWMP GVNDCDLLMY LRAARSMAAF AGMCDGGSTE DGCVAASRDD TTLNALNTLH ESGYDAGKAL QRLVKKPVPK LIEKCWTEDE VKRFVKGLRQ YGKNFFRIRK ELLPNKETGE LITFYYYWKK TPEAASSRAH RRHRRQAVFR RIKTRTASTP VNTPSRPPSS EFLDLSSASE DDFDSEDSEQ ELKGYACRHC FTTTSKDWHH GGRENILLCT DCRIHFKKYG ELPPIEKPVD PPPFMFKPVK EEDDGLSGKH SMRTRRSRGS MSTLRSGRKK QPASPDGRTS PINEDIRSSG RNSPSAASTS SNDSKAETVK KSAKKVKEEA SSPLKSNKRQ REKVASDTEE ADRTSSKKTK TQEISRPNSP SEGEGESSDS RSVNDEGSSD PKDIDQDNRS TSPSIPSPQD NESDSDSSAQ QQMLQAQPPA LQAPTGVTPA PSSAPPGTPQ LPTPGPTPSA TAVPPQGSPT ASQAPNQPQA PTAPVPHTHI QQAPALHPQR PPSPHPPPHP SPHPPLQPLT GSAGQPSAPS HAQPPLHGQG PPGPHSLQAG PLLQHPGPPQ PFGLPPQASQ GQAPLGTSPA AAYPHTSLQL PASQSALQSQ QPPREQPLPP APLAMPHIKP PPTTPIPQLP APQAHKHPPH LSGPSPFSMN ANLPPPPALK PLSSLSTHHP PSAHPPPLQL MPQSQPLPSS PAQPPGLTQS QNLPPPPASH PPTGLHQVAP QPPFAQHPFV PGGPPPITPP TCPSTSTPPA GPGTSAQPPC SGAAASGGSI AGGSSCPLPT VQIKEEALDD AEEPESPPPP PRSPSPEPTV VDTPSHASQS ARFYKHLDRG YNSCARTDLY FMPLAGSKLA KKREEAIEKA KREAEQKARE EREREKEKEK ERERERERER EAERAAKASS SAHEGRLSDP QLSGPGHMRP SFEPPPTTIA AVPPYIGPDT PALRTLSEYA RPHVMSPTNR NHPFYMPLNP TDPLLAYHMP GLYNVDPTIR ERELREREIR EREIRERELR ERMKPGFEVK PPELDPLHPA ANPMEHFARH SALTIPPTAG PHPFASFHPG LNPLERERLA LAGPQLRPEM SYPDRLAAER IHAERMASLT SDPLARLQMF NVTPHHHQHS HIHSHLHLHQ QDPLHQGSAG PVHPLVDPLT AGPHLARFPY PPGTLPNPLL GQPPHEHEML RHPVFGTPYP RDLPGAIPPP MSAAHQLQAM HAQSAELQRL AMEQQWLHGH PHMHGGHLPS QEDYYSRLKK EGDKQL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.