ATOH1 | ENSG00000172238 | NCBI 474

Details for: ATOH1

Gene ID: 474

Symbol: ATOH1

Ensembl ID: ENSG00000172238

Description: atonal bHLH transcription factor 1

Associated with

Auditory receptor cell fate determination
(GO:0042668)
Auditory receptor cell fate specification
(GO:0042667)
Axon development
(GO:0061564)
Axon guidance
(GO:0007411)
Central nervous system development
(GO:0007417)
Cerebral cortex development
(GO:0021987)
Chromatin
(GO:0000785)
Chromatin dna binding
(GO:0031490)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
E-box binding
(GO:0070888)
Epithelial cell apoptotic process
(GO:1904019)
Inner ear morphogenesis
(GO:0042472)
Negative regulation of epithelial cell apoptotic process
(GO:1904036)
Negative regulation of gliogenesis
(GO:0014014)
Neuroblast migration
(GO:0097402)
Neuron fate commitment
(GO:0048663)
Neuron migration
(GO:0001764)
Notch signaling pathway
(GO:0007219)
Nucleus
(GO:0005634)
Positive regulation of inner ear auditory receptor cell differentiation
(GO:0045609)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein dimerization activity
(GO:0046983)
Sensory organ development
(GO:0007423)
Sequence-specific double-stranded dna binding
(GO:1990837)
Transcription by rna polymerase ii
(GO:0006366)

Other Information

Proteins

ATOH1_HUMAN

Genular Protein ID: 1290922275

Symbol: ATOH1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q92858 Q14CT9

Database IDs:

Citations:

PubMed ID: 8872459

Title: Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis.

PubMed ID: 8872459

DOI: 10.1093/hmg/5.9.1207

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 33111345

Title: Spectrum of genes for inherited hearing loss in the Israeli Jewish population, including the novel human deafness gene ATOH1.

PubMed ID: 33111345

DOI: 10.1111/cge.13817

Sequence Information:

Length: 354
Mass: 38160
Checksum: AB12F1E917A00A8D
Sequence:

MSRLLHAEEW AEVKELGDHH RQPQPHHLPQ PPPPPQPPAT LQAREHPVYP PELSLLDSTD 
PRAWLAPTLQ GICTARAAQY LLHSPELGAS EAAAPRDEVD GRGELVRRSS GGASSSKSPG 
PVKVREQLCK LKGGVVVDEL GCSRQRAPSS KQVNGVQKQR RLAANARERR RMHGLNHAFD 
QLRNVIPSFN NDKKLSKYET LQMAQIYINA LSELLQTPSG GEQPPPPPAS CKSDHHHLRT 
AASYEGGAGN ATAAGAQQAS GGSQRPTPPG SCRTRFSAPA SAGGYSVQLD ALHFSTFEDS 
ALTAMMAQKN LSPSLPGSIL QPVQEENSKT SPRSHRSDGE FSPHSHYSDS DEAS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.