Details for: ATP12A
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 18.2540
Cell Significance Index: -4.6300 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 5.1923
Cell Significance Index: 53.5600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 4.4305
Cell Significance Index: -4.2300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 2.2233
Cell Significance Index: 136.3100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.0516
Cell Significance Index: -4.4900 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 1.3702
Cell Significance Index: 33.1900 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.0779
Cell Significance Index: 12.5300 - Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
Fold Change: 0.9180
Cell Significance Index: 6.1300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.8848
Cell Significance Index: 19.1700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.6019
Cell Significance Index: 114.5500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4796
Cell Significance Index: 21.7400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4747
Cell Significance Index: 46.9600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.4553
Cell Significance Index: 9.9700 - Cell Name: urothelial cell (CL0000731)
Fold Change: 0.4531
Cell Significance Index: 3.1600 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: 0.4447
Cell Significance Index: 4.4500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3762
Cell Significance Index: 339.7200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.2709
Cell Significance Index: 8.6800 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.2663
Cell Significance Index: 4.1200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2397
Cell Significance Index: 38.9900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.2199
Cell Significance Index: 3.0000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1971
Cell Significance Index: 21.4400 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 0.1956
Cell Significance Index: 2.9700 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: 0.1751
Cell Significance Index: 2.5500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.1686
Cell Significance Index: 3.5900 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 0.1657
Cell Significance Index: 1.3700 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.1604
Cell Significance Index: 1.0700 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 0.0971
Cell Significance Index: 1.6000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0904
Cell Significance Index: 6.2600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0840
Cell Significance Index: 1.4400 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 0.0698
Cell Significance Index: 0.6200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.0641
Cell Significance Index: 3.8500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0456
Cell Significance Index: 6.6400 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.0453
Cell Significance Index: 0.3900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0382
Cell Significance Index: 6.8900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0283
Cell Significance Index: 0.4100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0264
Cell Significance Index: 0.7600 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 0.0242
Cell Significance Index: 0.2300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0206
Cell Significance Index: 4.1300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0195
Cell Significance Index: 0.5000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0194
Cell Significance Index: 0.6800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0176
Cell Significance Index: 0.4900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0064
Cell Significance Index: 12.0800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0056
Cell Significance Index: 1.1200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0018
Cell Significance Index: 2.7300 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0001
Cell Significance Index: -0.1500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0004
Cell Significance Index: -0.7000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0006
Cell Significance Index: -0.0700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0021
Cell Significance Index: -0.7400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0024
Cell Significance Index: -1.5500 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: -0.0036
Cell Significance Index: -0.0500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0044
Cell Significance Index: -0.1100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0045
Cell Significance Index: -3.3700 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0053
Cell Significance Index: -0.6800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0056
Cell Significance Index: -4.1500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0061
Cell Significance Index: -4.4700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0075
Cell Significance Index: -4.2400 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0077
Cell Significance Index: -4.1800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0090
Cell Significance Index: -4.0700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0091
Cell Significance Index: -1.5500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0096
Cell Significance Index: -2.7700 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0198
Cell Significance Index: -0.8600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0207
Cell Significance Index: -4.3600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0240
Cell Significance Index: -2.9500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0305
Cell Significance Index: -4.1900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0309
Cell Significance Index: -0.6400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0327
Cell Significance Index: -3.8100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0412
Cell Significance Index: -2.7700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0427
Cell Significance Index: -4.4500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0470
Cell Significance Index: -4.8000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0473
Cell Significance Index: -2.9100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0474
Cell Significance Index: -2.1000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0573
Cell Significance Index: -2.1700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0592
Cell Significance Index: -4.6900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0696
Cell Significance Index: -5.3400 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0717
Cell Significance Index: -1.0800 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0749
Cell Significance Index: -2.7500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0801
Cell Significance Index: -4.1600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0826
Cell Significance Index: -4.3000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0905
Cell Significance Index: -3.1700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0915
Cell Significance Index: -2.6100 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0944
Cell Significance Index: -1.1300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0945
Cell Significance Index: -3.0100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0952
Cell Significance Index: -2.5900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0990
Cell Significance Index: -3.2400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0996
Cell Significance Index: -4.6800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0996
Cell Significance Index: -4.6500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1021
Cell Significance Index: -5.7300 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1052
Cell Significance Index: -3.1000 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.1059
Cell Significance Index: -2.6400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1080
Cell Significance Index: -2.8900 - Cell Name: secretory cell (CL0000151)
Fold Change: -0.1082
Cell Significance Index: -0.7500 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.1138
Cell Significance Index: -3.6000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1154
Cell Significance Index: -6.0600 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.1245
Cell Significance Index: -3.1100 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.1300
Cell Significance Index: -1.8500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1332
Cell Significance Index: -3.5700 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.1335
Cell Significance Index: -2.6100 - Cell Name: lung secretory cell (CL1000272)
Fold Change: -0.1392
Cell Significance Index: -1.0600 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1447
Cell Significance Index: -3.6100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1480
Cell Significance Index: -3.9600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 953807484
Symbol: AT12A_HUMAN
Name: Potassium-transporting ATPase alpha chain 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8045293
Title: Cloning and characterization of the entire cDNA encoded by ATP1AL1 -- a member of the human Na,K/H,K-ATPase gene family.
PubMed ID: 8045293
PubMed ID: 8838794
Title: Genomic organization of the human ATP1AL1 gene encoding a ouabain-sensitive H,K-ATPase.
PubMed ID: 8838794
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1847115
Title: The family of human Na,K-ATPase genes. ATP1AL1 gene is transcriptionally competent and probably encodes the related ion transport ATPase.
PubMed ID: 1847115
PubMed ID: 3035563
Title: Multiple genes encode the human Na+,K+-ATPase catalytic subunit.
PubMed ID: 3035563
PubMed ID: 3036582
Title: The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.
PubMed ID: 3036582
PubMed ID: 7485470
Title: Human ATP1AL1 gene encodes a ouabain-sensitive H-K-ATPase.
PubMed ID: 7485470
PubMed ID: 8853415
Title: Functional expression of the cDNA encoded by the human ATP1AL1 gene.
PubMed ID: 8853415
PubMed ID: 9872395
Title: Ouabain-sensitive H,K-ATPase: tissue-specific expression of the mammalian genes encoding the catalytic alpha subunit.
PubMed ID: 9872395
PubMed ID: 9774385
Title: ATP1AL1, a member of the non-gastric H,K-ATPase family, functions as a sodium pump.
PubMed ID: 9774385
PubMed ID: 11341842
Title: Catalytic function of nongastric H,K-ATPase expressed in Sf-21 insect cells.
PubMed ID: 11341842
DOI: 10.1021/bi010191y
PubMed ID: 16914892
Title: An extracellular loop of the human non-gastric H,K-ATPase alpha-subunit is involved in apical plasma membrane polarization.
PubMed ID: 16914892
DOI: 10.1159/000095169
PubMed ID: 22179016
Title: Expression of the non-gastric H+/K+ ATPase ATP12A in normal and pathological human prostate tissue.
PubMed ID: 22179016
DOI: 10.1159/000335860
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 29391451
Title: ATP12A promotes mucus dysfunction during Type 2 airway inflammation.
PubMed ID: 29391451
Sequence Information:
- Length: 1039
- Mass: 115511
- Checksum: C906897E11FA406C
- Sequence:
MHQKTPEIYS VELSGTKDIV KTDKGDGKEK YRGLKNNCLE LKKKNHKEEF QKELHLDDHK LSNRELEEKY GTDIIMGLSS TRAAELLARD GPNSLTPPKQ TPEIVKFLKQ MVGGFSILLW VGAFLCWIAY GIQYSSDKSA SLNNVYLGCV LGLVVILTGI FAYYQEAKST NIMSSFNKMI PQQALVIRDS EKKTIPSEQL VVGDIVEVKG GDQIPADIRV LSSQGCRVDN SSLTGESEPQ PRSSEFTHEN PLETKNICFY STTCLEGTVT GMVINTGDRT IIGHIASLAS GVGNEKTPIA IEIEHFVHIV AGVAVSIGIL FFIIAVSLKY QVLDSIIFLI GIIVANVPEG LLATVTVTLS LTAKRMAKKN CLVKNLEAVE TLGSTSIICS DKTGTLTQNR MTVAHLWFDN QIFVADTSED HSNQVFDQSS RTWASLSKII TLCNRAEFKP GQENVPIMKK AVIGDASETA LLKFSEVILG DVMEIRKRNR KVAEIPFNST NKFQLSIHEM DDPHGKRFLM VMKGAPERIL EKCSTIMING EEHPLDKSTA KTFHTAYMEL GGLGERVLGF CHLYLPADEF PETYSFDIDA MNFPTSNLCF VGLLSMIDPP RSTVPDAVTK CRSAGIKVIM VTGDHPITAK AIAKSVGIIS ANSETVEDIA HRLNIAVEQV NKRDAKAAVV TGMELKDMSS EQLDEILANY QEIVFARTSP QQKLIIVEGC QRQDAVVAVT GDGVNDSPAL KKADIGIAMG IAGSDAAKNA ADMVLLDDNF ASIVTGVEEG RLIFDNLKKT IAYSLTKNIA ELCPFLIYII VGLPLPIGTI TILFIDLGTD IIPSIALAYE KAESDIMNRK PRHKNKDRLV NQPLAVYSYL HIGLMQALGA FLVYFTVYAQ EGFLPRTLIN LRVEWEKDYV NDLKDSYGQE WTRYQREYLE WTGYTAFFVG ILVQQIADLI IRKTRRNSIF QQGLFRNKVI WVGITSQIII GLILSYGLGS VTALSFTMLR AQYWFVAVPH AILIWVYDEV RKLFIRLYPG SWWDKNMYY
Genular Protein ID: 4267167982
Symbol: B4E0R9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 674
- Mass: 75572
- Checksum: 963FA54CEBE95C19
- Sequence:
MAKKNCLVKN LEAVETLGST SIICSDKTGT LTQNRMTVAH LWFDNQIFVA DTSEDHSNQV FDQSSRTWAS LSKIITLCNR AEFKPGQENV PIMKKAVIGD ASETALLKFS EVILGDVMEI RKRNRKVAEI PFNSTNKFQL SIHEMDDPHG KRFLMVMKGA PERILEKCST IMINGEEHLL DKSTAKTFHT AYMELGGLGE RVLGFCHLYL PADEFPETYS FDIDAMNFPT SNLCFVGLLS MIDPPRSTVP DAVTKCRSAG IKVIMVTGDH PITAKAIAKS VGIISANSET VEDIAHRLNI AVEQVNKRDA KAAVVTSMEL KDMSSEQLDE ILANYQEIVF ARTSPQQKLI IVEGCQRQDA VVAVTGDGVN DSPALKKADI GIAMGIAGSD AAKNAADMVL LDDNFASTVT GVEEGRLIFD NLKKTIAYSL TKNIAELCPF LIYIIVGLPL PIGTITILFI DLGTDIIPSI ALAYEKAESD IMNRKPRHKN KDRLVNQPLA VYSYLHIGLM QALGAFLVYF TVYAQEGFLP RTLINLRVEW EKDYVNDLKD SYGQEWTRYQ REYLEWTGYT AFFVGILVQQ IADLIIRKTR RNSIFQQGLF RNKVIWVGIT SQIIIGLILS YGLGSVTALS FTMLRAQYWF VAVPHAILIW VYDEVRKLFI RLYPGSWWDK NMYY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.