Details for: ACO1

Gene ID: 48

Symbol: ACO1

Ensembl ID: ENSG00000122729

Description: aconitase 1

Associated with

Other Information

Genular Protein ID: 1610431017

Symbol: ACOHC_HUMAN

Name: Citrate hydro-lyase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1738601

Title: Expression of active iron regulatory factor from a full-length human cDNA by in vitro transcription/translation.

PubMed ID: 1738601

DOI: 10.1093/nar/20.1.33

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2172968

Title: Cloning of the cDNA encoding an RNA regulatory protein -- the human iron-responsive element-binding protein.

PubMed ID: 2172968

DOI: 10.1073/pnas.87.20.7958

PubMed ID: 1903202

Title: Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase.

PubMed ID: 1903202

DOI: 10.1093/nar/19.8.1739

PubMed ID: 1946430

Title: A regulated RNA binding protein also possesses aconitase activity.

PubMed ID: 1946430

DOI: 10.1073/pnas.88.22.10109

PubMed ID: 1281544

Title: Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding.

PubMed ID: 1281544

DOI: 10.1073/pnas.89.24.11735

PubMed ID: 8041788

Title: The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation.

PubMed ID: 8041788

DOI: 10.1073/pnas.91.15.7321

PubMed ID: 19762596

Title: Control of iron homeostasis by an iron-regulated ubiquitin ligase.

PubMed ID: 19762596

DOI: 10.1126/science.1176333

PubMed ID: 19762597

Title: An E3 ligase possessing an iron responsive hemerythrin domain is a regulator of iron homeostasis.

PubMed ID: 19762597

DOI: 10.1126/science.1176326

PubMed ID: 20053667

Title: Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin.

PubMed ID: 20053667

DOI: 10.1093/hmg/ddp592

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23891004

Title: Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.

PubMed ID: 23891004

DOI: 10.1016/j.cmet.2013.06.015

PubMed ID: 29320706

Title: Human CIA2A-FAM96A and CIA2B-FAM96B Integrate Iron Homeostasis and Maturation of Different Subsets of Cytosolic-Nuclear Iron-Sulfur Proteins.

PubMed ID: 29320706

DOI: 10.1016/j.cmet.2017.12.009

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 16407072

Title: Crystal structure of human iron regulatory protein 1 as cytosolic aconitase.

PubMed ID: 16407072

DOI: 10.1016/j.str.2005.09.009

PubMed ID: 23033978

Title: Diagnostic exome sequencing in persons with severe intellectual disability.

PubMed ID: 23033978

DOI: 10.1056/nejmoa1206524

Sequence Information:

  • Length: 889
  • Mass: 98399
  • Checksum: E1A05AF701D46DCB
  • Sequence:
  • MSNPFAHLAE PLDPVQPGKK FFNLNKLEDS RYGRLPFSIR VLLEAAIRNC DEFLVKKQDI 
    ENILHWNVTQ HKNIEVPFKP ARVILQDFTG VPAVVDFAAM RDAVKKLGGD PEKINPVCPA 
    DLVIDHSIQV DFNRRADSLQ KNQDLEFERN RERFEFLKWG SQAFHNMRII PPGSGIIHQV 
    NLEYLARVVF DQDGYYYPDS LVGTDSHTTM IDGLGILGWG VGGIEAEAVM LGQPISMVLP 
    QVIGYRLMGK PHPLVTSTDI VLTITKHLRQ VGVVGKFVEF FGPGVAQLSI ADRATIANMC 
    PEYGATAAFF PVDEVSITYL VQTGRDEEKL KYIKKYLQAV GMFRDFNDPS QDPDFTQVVE 
    LDLKTVVPCC SGPKRPQDKV AVSDMKKDFE SCLGAKQGFK GFQVAPEHHN DHKTFIYDNT 
    EFTLAHGSVV IAAITSCTNT SNPSVMLGAG LLAKKAVDAG LNVMPYIKTS LSPGSGVVTY 
    YLQESGVMPY LSQLGFDVVG YGCMTCIGNS GPLPEPVVEA ITQGDLVAVG VLSGNRNFEG 
    RVHPNTRANY LASPPLVIAY AIAGTIRIDF EKEPLGVNAK GQQVFLKDIW PTRDEIQAVE 
    RQYVIPGMFK EVYQKIETVN ESWNALATPS DKLFFWNSKS TYIKSPPFFE NLTLDLQPPK 
    SIVDAYVLLN LGDSVTTDHI SPAGNIARNS PAARYLTNRG LTPREFNSYG SRRGNDAVMA 
    RGTFANIRLL NRFLNKQAPQ TIHLPSGEIL DVFDAAERYQ QAGLPLIVLA GKEYGAGSSR 
    DWAAKGPFLL GIKAVLAESY ERIHRSNLVG MGVIPLEYLP GENADALGLT GQERYTIIIP 
    ENLKPQMKVQ VKLDTGKTFQ AVMRFDTDVE LTYFLNGGIL NYMIRKMAK

Genular Protein ID: 574578564

Symbol: Q9HBB2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10944468

Title: cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs.

PubMed ID: 10944468

DOI: 10.1006/bbrc.2000.3282

Sequence Information:

  • Length: 790
  • Mass: 87089
  • Checksum: 4DEE8385DCA07C77
  • Sequence:
  • MRDAVKKLGG DPEKINPVCP ADLVIDHSIQ VDFNRRADSL QKNQDLEFER NRERFEFLKW 
    GSQAFHNMRI IPPGSGIIHQ VNLEYLARVV FDQDGYYYPD SLVGTDSHTT MIDGLGILGW 
    GVGGIEAEAV MLGQPISMVL PQVIGYRLMG KPHPLVTSTD IVLTITKHLR QVGVVGKFVE 
    FFGPGVAQLS IADRATIANM CPEYGATAAF FPVDEVSITY LVQTGRDEEK LKYIKKYLQA 
    VGMFRDFNDP SQDPDFTQVV ELDLKTVVPC CSGPKRPQDK VAVSDMKKDF ESCLGAKQGF 
    KGFQVAPEHH NDHKTFIYDN TEFTLAHGSV VIAAITSCTN TSNPSVMLGA GLLAKKAVDA 
    GLNVMPYIKT SLSPGSGVVT YYLQESGVMP YLSQLGFDVV GYGCMTCIGN SGPLPEPVVE 
    AITQGDLVAV GVLSGNRNFE GRVHPNTRAN YLASPPLVIA YAIAGTIRID FEKEPLGVNA 
    KGQQVFLKDI WPTRDEIQAV ERQYVIPGMF KEVYQKIETV NESWNALATP SDKLFFWNSK 
    STYIKSPPFF ENLTLDLQPP KSIVDAYVLL NLGDSVTTDH ISPAGNIARN SPAARYLTNR 
    GLTPREFNSY GSRRGNDAVM ARGTFANIRL LNRFLNKQAP QTIHLPSGEI LDVFDAAERY 
    QQAGLPLIVL AGKEYGAGSS RDWAAKGPFL LGIKAVLAES YERIHRSNLV GMGVIPLEYL 
    PGENADALGL TGQERYTIII PENLKPQMKV QVKLDTGKTF QAVMRFDTDV ELTYFLNGGI 
    LNYMIRKMAK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.