ATP1A4 | ENSG00000132681 | NCBI 480

Details for: ATP1A4

Gene ID: 480

Symbol: ATP1A4

Ensembl ID: ENSG00000132681

Description: ATPase Na+/K+ transporting subunit alpha 4

Associated with

Cardiac conduction
(R-HSA-5576891)
Disease
(R-HSA-1643685)
Infectious disease
(R-HSA-5663205)
Ion channel transport
(R-HSA-983712)
Ion homeostasis
(R-HSA-5578775)
Ion transport by p-type atpases
(R-HSA-936837)
Muscle contraction
(R-HSA-397014)
Potential therapeutics for sars
(R-HSA-9679191)
Sars-cov infections
(R-HSA-9679506)
Transport of small molecules
(R-HSA-382551)
Viral infection pathways
(R-HSA-9824446)
Atpase-coupled monoatomic cation transmembrane transporter activity
(GO:0019829)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cell projection
(GO:0042995)
Cell surface receptor signaling pathway
(GO:0007166)
Establishment of localization in cell
(GO:0051649)
Establishment or maintenance of transmembrane electrochemical gradient
(GO:0010248)
Fertilization
(GO:0009566)
Flagellated sperm motility
(GO:0030317)
Intracellular potassium ion homeostasis
(GO:0030007)
Intracellular sodium ion homeostasis
(GO:0006883)
Kinase binding
(GO:0019900)
Membrane raft
(GO:0045121)
Metal ion binding
(GO:0046872)
Monoatomic ion transport
(GO:0006811)
P-type sodium:potassium-exchanging transporter activity
(GO:0005391)
Photoreceptor cell cilium
(GO:0097733)
Plasma membrane
(GO:0005886)
Potassium ion import across plasma membrane
(GO:1990573)
Potassium ion transmembrane transport
(GO:0071805)
Potassium ion transport
(GO:0006813)
Protein binding
(GO:0005515)
Proton transmembrane transport
(GO:1902600)
Regulation of cellular ph
(GO:0030641)
Regulation of membrane potential
(GO:0042391)
Rod photoreceptor outer segment
(GO:0120200)
Sodium:potassium-exchanging atpase complex
(GO:0005890)
Sodium ion export across plasma membrane
(GO:0036376)
Sodium ion transmembrane transport
(GO:0035725)
Sodium ion transport
(GO:0006814)
Spermatogenesis
(GO:0007283)
Sperm midpiece
(GO:0097225)
Transport across blood-brain barrier
(GO:0150104)

Other Information

Proteins

Sodium pump subunit alpha-4

Genular Protein ID: 2980181749

Symbol: AT1A4_HUMAN

Name: Sodium pump subunit alpha-4

UniProtKB Accession Codes:

Q13733 Q504T2 Q7Z4I9 Q8TBN8 Q8WXA7 Q8WXH7 Q8WY13

Database IDs:

Citations:

PubMed ID: 16175638

Title: The human Na,K-ATPase alpha 4 isoform is a ouabain-sensitive alpha isoform that is expressed in sperm.

PubMed ID: 16175638

DOI: 10.1002/mrd.20383

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12119109

Title: Physical mapping and characterization of the human Na,K-ATPase isoform, ATP1A4.

PubMed ID: 12119109

DOI: 10.1016/s0378-1119(02)00647-9

PubMed ID: 7809153

Title: A putative fourth Na+,K(+)-ATPase alpha-subunit gene is expressed in testis.

PubMed ID: 7809153

DOI: 10.1073/pnas.91.26.12952

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

Length: 1029
Mass: 114166
Checksum: 69958248424D2C0B
Sequence:

MGLWGKKGTV APHDQSPRRR PKKGLIKKKM VKREKQKRNM EELKKEVVMD DHKLTLEELS 
TKYSVDLTKG HSHQRAKEIL TRGGPNTVTP PPTTPEWVKF CKQLFGGFSL LLWTGAILCF 
VAYSIQIYFN EEPTKDNLYL SIVLSVVVIV TGCFSYYQEA KSSKIMESFK NMVPQQALVI 
RGGEKMQINV QEVVLGDLVE IKGGDRVPAD LRLISAQGCK VDNSSLTGES EPQSRSPDFT 
HENPLETRNI CFFSTNCVEG TARGIVIATG DSTVMGRIAS LTSGLAVGQT PIAAEIEHFI 
HLITVVAVFL GVTFFALSLL LGYGWLEAII FLIGIIVANV PEGLLATVTV CLTLTAKRMA 
RKNCLVKNLE AVETLGSTST ICSDKTGTLT QNRMTVAHMW FDMTVYEADT TEEQTGKTFT 
KSSDTWFMLA RIAGLCNRAD FKANQEILPI AKRATTGDAS ESALLKFIEQ SYSSVAEMRE 
KNPKVAEIPF NSTNKYQMSI HLREDSSQTH VLMMKGAPER ILEFCSTFLL NGQEYSMNDE 
MKEAFQNAYL ELGGLGERVL GFCFLNLPSS FSKGFPFNTD EINFPMDNLC FVGLISMIDP 
PRAAVPDAVS KCRSAGIKVI MVTGDHPITA KAIAKGVGII SEGTETAEEV AARLKIPISK 
VDASAAKAIV VHGAELKDIQ SKQLDQILQN HPEIVFARTS PQQKLIIVEG CQRLGAVVAV 
TGDGVNDSPA LKKADIGIAM GISGSDVSKQ AADMILLDDN FASIVTGVEE GRLIFDNLKK 
SIMYTLTSNI PEITPFLMFI ILGIPLPLGT ITILCIDLGT DMVPAISLAY ESAESDIMKR 
LPRNPKTDNL VNHRLIGMAY GQIGMIQALA GFFTYFVILA ENGFRPVDLL GIRLHWEDKY 
LNDLEDSYGQ QWTYEQRKVV EFTCQTAFFV TIVVVQWADL IISKTRRNSL FQQGMRNKVL 
IFGILEETLL AAFLSYTPGM DVALRMYPLK ITWWLCAIPY SILIFVYDEI RKLLIRQHPD 
GWVERETYY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ATP1A4

Associated with

Other Information

The human Na,K-ATPase alpha 4 isoform is a ouabain-sensitive alpha isoform that is expressed in sperm. PubMed ID: 16175638

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Physical mapping and characterization of the human Na,K-ATPase isoform, ATP1A4. PubMed ID: 12119109

A putative fourth Na+,K(+)-ATPase alpha-subunit gene is expressed in testis. PubMed ID: 7809153