ATP1B1 | ENSG00000143153 | NCBI 481

Details for: ATP1B1

Gene ID: 481

Symbol: ATP1B1

Ensembl ID: ENSG00000143153

Description: ATPase Na+/K+ transporting subunit beta 1

Associated with

Basigin interactions
(R-HSA-210991)
Cardiac conduction
(R-HSA-5576891)
Cell surface interactions at the vascular wall
(R-HSA-202733)
Disease
(R-HSA-1643685)
Hemostasis
(R-HSA-109582)
Infectious disease
(R-HSA-5663205)
Ion channel transport
(R-HSA-983712)
Ion homeostasis
(R-HSA-5578775)
Ion transport by p-type atpases
(R-HSA-936837)
Muscle contraction
(R-HSA-397014)
Potential therapeutics for sars
(R-HSA-9679191)
Sars-cov infections
(R-HSA-9679506)
Transport of small molecules
(R-HSA-382551)
Viral infection pathways
(R-HSA-9824446)
Apical plasma membrane
(GO:0016324)
Atpase activator activity
(GO:0001671)
Atpase binding
(GO:0051117)
Atp metabolic process
(GO:0046034)
Basolateral plasma membrane
(GO:0016323)
Cardiac muscle contraction
(GO:0060048)
Cell adhesion
(GO:0007155)
Cell communication by electrical coupling involved in cardiac conduction
(GO:0086064)
Establishment or maintenance of transmembrane electrochemical gradient
(GO:0010248)
Extracellular exosome
(GO:0070062)
Extracellular vesicle
(GO:1903561)
Innate immune response
(GO:0045087)
Intercalated disc
(GO:0014704)
Intracellular calcium ion homeostasis
(GO:0006874)
Intracellular potassium ion homeostasis
(GO:0030007)
Intracellular sodium ion homeostasis
(GO:0006883)
Lateral plasma membrane
(GO:0016328)
Membrane
(GO:0016020)
Membrane repolarization
(GO:0086009)
Membrane repolarization during cardiac muscle cell action potential
(GO:0086013)
Mhc class ii protein complex binding
(GO:0023026)
Monoatomic cation transmembrane transport
(GO:0098655)
Organelle membrane
(GO:0031090)
P-type sodium:potassium-exchanging transporter activity
(GO:0005391)
Plasma membrane
(GO:0005886)
Positive regulation of atp-dependent activity
(GO:0032781)
Positive regulation of calcium:sodium antiporter activity
(GO:1903281)
Positive regulation of p-type sodium:potassium-exchanging transporter activity
(GO:1903408)
Positive regulation of potassium ion import across plasma membrane
(GO:1903288)
Positive regulation of potassium ion transmembrane transporter activity
(GO:1901018)
Positive regulation of sodium ion export across plasma membrane
(GO:1903278)
Potassium ion import across plasma membrane
(GO:1990573)
Protein-macromolecule adaptor activity
(GO:0030674)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Protein kinase binding
(GO:0019901)
Protein localization to plasma membrane
(GO:0072659)
Protein stabilization
(GO:0050821)
Protein transport into plasma membrane raft
(GO:0044861)
Proton transmembrane transport
(GO:1902600)
Regulation of cardiac muscle contraction by calcium ion signaling
(GO:0010882)
Regulation of gene expression
(GO:0010468)
Relaxation of cardiac muscle
(GO:0055119)
Sarcolemma
(GO:0042383)
Sodium:potassium-exchanging atpase complex
(GO:0005890)
Sodium ion export across plasma membrane
(GO:0036376)
Sodium ion transmembrane transport
(GO:0035725)
Sperm flagellum
(GO:0036126)
T-tubule
(GO:0030315)

Other Information

Proteins

Sodium/potassium-transporting ATPase subunit beta-1

Genular Protein ID: 3869103526

Symbol: AT1B1_HUMAN

Name: Sodium/potassium-transporting ATPase subunit beta-1

UniProtKB Accession Codes:

P05026 Q5TGZ3

Database IDs:

Citations:

PubMed ID: 3008098

Title: Molecular cloning and sequence analysis of human Na,K-ATPase beta-subunit.

PubMed ID: 3008098

DOI: 10.1093/nar/14.7.2833

PubMed ID: 2559024

Title: Characterization of two genes for the human Na,K-ATPase beta subunit.

PubMed ID: 2559024

DOI: 10.1016/0888-7543(89)90008-6

PubMed ID: 7536695

Title: Characterization and quantification of full-length and truncated Na,K-ATPase alpha 1 and beta 1 RNA transcripts expressed in human retinal pigment epithelium.

PubMed ID: 7536695

DOI: 10.1016/0378-1119(94)00812-7

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2555225

Title: Human Na(+), K(+)-ATPase genes. Beta subunit gene family contains at least one gene and one pseudogene.

PubMed ID: 2555225

DOI: 10.1016/0014-5793(89)81591-1

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 19694409

Title: A C-terminal lobe of the beta subunit of Na,K-ATPase and H,K-ATPase resembles cell adhesion molecules.

PubMed ID: 19694409

DOI: 10.1021/bi900868e

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22328087

Title: Megalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutations.

PubMed ID: 22328087

DOI: 10.1093/hmg/dds032

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25902260

Title: Autism and intellectual disability-associated KIRREL3 interacts with neuronal proteins MAP1B and MYO16 with potential roles in neurodevelopment.

PubMed ID: 25902260

DOI: 10.1371/journal.pone.0123106

PubMed ID: 34011520

Title: Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.

PubMed ID: 34011520

DOI: 10.4049/jimmunol.2001262

Sequence Information:

Length: 303
Mass: 35061
Checksum: 107D3C04394F2D11
Sequence:

MARGKAKEEG SWKKFIWNSE KKEFLGRTGG SWFKILLFYV IFYGCLAGIF IGTIQVMLLT 
ISEFKPTYQD RVAPPGLTQI PQIQKTEISF RPNDPKSYEA YVLNIVRFLE KYKDSAQRDD 
MIFEDCGDVP SEPKERGDFN HERGERKVCR FKLEWLGNCS GLNDETYGYK EGKPCIIIKL 
NRVLGFKPKP PKNESLETYP VMKYNPNVLP VQCTGKRDED KDKVGNVEYF GLGNSPGFPL 
QYYPYYGKLL QPKYLQPLLA VQFTNLTMDT EIRIECKAYG ENIGYSEKDR FQGRFDVKIE 
VKS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ATP1B1

Associated with

Other Information

Molecular cloning and sequence analysis of human Na,K-ATPase beta-subunit. PubMed ID: 3008098

Characterization of two genes for the human Na,K-ATPase beta subunit. PubMed ID: 2559024

Characterization and quantification of full-length and truncated Na,K-ATPase alpha 1 and beta 1 RNA transcripts expressed in human retinal pigment epithelium. PubMed ID: 7536695

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Human Na(+), K(+)-ATPase genes. Beta subunit gene family contains at least one gene and one pseudogene. PubMed ID: 2555225

Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. PubMed ID: 12754519

A C-terminal lobe of the beta subunit of Na,K-ATPase and H,K-ATPase resembles cell adhesion molecules. PubMed ID: 19694409

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

Initial characterization of the human central proteome. PubMed ID: 21269460

Megalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutations. PubMed ID: 22328087

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Autism and intellectual disability-associated KIRREL3 interacts with neuronal proteins MAP1B and MYO16 with potential roles in neurodevelopment. PubMed ID: 25902260

Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6. PubMed ID: 34011520