Details for: ttk

Gene ID: 48317

Symbol: ttk

Ensembl ID: FBgn0003870

Description: tramtrack

Associated with

  • Branch fusion, open tracheal system
    (GO:0035147)
  • Branching involved in open tracheal system development
    (GO:0060446)
  • Chitin-based cuticle development
    (GO:0040003)
  • Chromatin binding
    (GO:0003682)
  • Compound eye cone cell differentiation
    (GO:0042675)
  • Compound eye corneal lens morphogenesis
    (GO:0048750)
  • Dendrite regeneration
    (GO:0031104)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Dorsal appendage formation
    (GO:0046843)
  • Dorsal trunk growth, open tracheal system
    (GO:0035001)
  • Eggshell chorion gene amplification
    (GO:0007307)
  • Enteroendocrine cell differentiation
    (GO:0035883)
  • Epidermal growth factor receptor signaling pathway
    (GO:0007173)
  • Follicle cell of egg chamber development
    (GO:0030707)
  • Myoblast fate specification
    (GO:0048626)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of photoreceptor cell differentiation
    (GO:0046533)
  • Negative regulation of r7 cell differentiation
    (GO:0045677)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Peripheral nervous system development
    (GO:0007422)
  • Polytene chromosome
    (GO:0005700)
  • Positive regulation of border follicle cell migration
    (GO:1903688)
  • Positive regulation of dna binding
    (GO:0043388)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Poz domain binding
    (GO:0031208)
  • Promoter-specific chromatin binding
    (GO:1990841)
  • Protein binding
    (GO:0005515)
  • Protein homodimerization activity
    (GO:0042803)
  • R1/r6 development
    (GO:0048053)
  • R7 cell development
    (GO:0045467)
  • Regulation of cell shape
    (GO:0008360)
  • Regulation of compound eye cone cell fate specification
    (GO:0042682)
  • Regulation of embryonic cell shape
    (GO:0016476)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Regulation of tube size, open tracheal system
    (GO:0035151)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sevenless signaling pathway
    (GO:0045500)
  • Tracheal outgrowth, open tracheal system
    (GO:0007426)
  • Transcription repressor complex
    (GO:0017053)

Other Information

Genular Protein ID: 1884010002

Symbol: TTKA_DROME

Name: Protein tramtrack, alpha isoform

UniProtKB Accession Codes:

P42282 A4V3Q3 Q0KHY0 Q1LZ43 Q24313 Q9V9V2

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 7 EnsemblMetazoa 4 ExpressionAtlas 1 FlyBase 1 GO 38 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PROSITE 3 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 RefSeq 4 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8504931

Title: Tramtrack is a transcriptional repressor required for cell fate determination in the Drosophila eye.

PubMed ID: 8504931

DOI: 10.1101/gad.7.6.1085

PubMed ID: 1372245

Title: Alternatively spliced transcripts of the Drosophila tramtrack gene encode zinc finger proteins with distinct DNA binding specificities.

PubMed ID: 1372245

DOI: 10.1002/j.1460-2075.1992.tb05142.x

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 15306652

Title: A conserved role but different partners for the transcriptional corepressor CoREST in fly and mammalian nervous system formation.

PubMed ID: 15306652

DOI: 10.1523/jneurosci.0238-04.2004

PubMed ID: 17962185

Title: Two modes of degradation of the tramtrack transcription factors by Siah homologues.

PubMed ID: 17962185

DOI: 10.1074/jbc.m707765200

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 813
  • Mass: 88383
  • Checksum: CF3EE14069C79AA2
  • Sequence:
    • MKMASQRFCL RWNNHQSNLL SVFDQLLHAE TFTDVTLAVE GQHLKAHKMV LSACSPYFNT 
LFVSHPEKHP IVILKDVPYS DMKSLLDFMY RGEVSVDQER LTAFLRVAES LRIKGLTEVN 
DDKPSPAAAA AGAGATGSES TATTPQLQRI QPYLVPQRNR SQAGGLLASA ANAGNTPTLP 
VQPSLLSSAL MPKRKRGRPR KLSGSSNGTG NDYDDFDREN MMNDSSDLGN GKMCNESYSG 
NDDGSDDNQP NAGHTDDLNE SRDSLPSKRS KNSKDHRVVS HHEDNSTSVT PTKATPELSQ 
RLFGSSSTTI SATAPGGSST GPSETISLLE ISDERESAPV HLPTILGLKI RAINTTTPAQ 
QGSPQTPTKS KPKIRQATGS NNSNSLLKQQ LRGGAKDPEV PPATRITGAV TPNAALNAEE 
QSKEMPKKNQ DEVNACIGLH SLANAAEQQA AQVASTGNLH HQLLLHMAAN NSMLNTTDYY 
QQQQQESPSS AGQFMDDDLE LLSLNDQQDK SDEPDHEMVT LADENAGLPG YQGNEAEATP 
AQEDSPAAET ATAPPPAPRS GKKGAKRPIQ RRRVRRKAQS TLDDQAEHLT EMSVRGLDLF 
RYASVVEGVY RCTECAKENM QKTFKNKYSF QRHAFLYHEG KHRKVFPCPV CSKEFSRPDK 
MKNHLKMTHE NFTPPKDIGA FSPLKYLISA AAAGDMHATI YQQQQDHYHR QLAEQLEQQN 
ASFDSRDSSL ILPDVKMEHA EDQDAEQEAE LSDGGYDASN PAAAAAAMLS LQQDVIIKDE 
IQISPSPSPT PPASCAVAEG KSLALASTAQ TAT

Genular Protein ID: 3936479314

Symbol: A0A0B4JD39_DROME

Name: N/A

UniProtKB Accession Codes:

A0A0B4JD39

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 EnsemblMetazoa 4 ExpressionAtlas 1 FlyBase 2 Gene3D 1 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 Pfam 2 Proteomes 2 RefSeq 4 SAM 1 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 643
  • Mass: 68771
  • Checksum: 98DAEA1A5E97DC59
  • Sequence:
    • MKMASQRFCL RWNNHQSNLL SVFDQLLHAE TFTDVTLAVE GQHLKAHKMV LSACSPYFNT 
LFVSHPEKHP IVILKDVPYS DMKSLLDFMY RGEVSVDQER LTAFLRVAES LRIKGLTEVN 
DDKPSPAAAA AGAGATGSES TATTPQLQRI QPYLVPQRNR SQAGGLLASA ANAGNTPTLP 
VQPSLLSSAL MPKRKRGRPR KLSGSSNGTG NDYDDFDREN MMNDSSDLGN GKMCNESYSG 
NDDGSDDNQP NAGHTDDLNE SRDSLPSKRS KNSKDHRVVS HHEDNSTSDG NDSDGEGLDT 
SYMEPQLMLD EYDEPVEFKY NPLTDNSSPT QDHTDGSHLN EQARQQAFLI AAQRKHQVET 
AAAAAASGIK LNIIGMAAGG AQVKSMVSIP KLTPIGKVNA ASTPLVSPAG SFSTATVKPR 
VQKRPKLGKQ NGDVKPAVFS SQEYLDIYNS NDGFKLKAAG LSGSTPNLSA GLGTPSVKTK 
LNLSSNVGEG EAEGSVRDYC TKEGEHTYRC KVCSRVYTHI SNFCRHYVTS HKRNVKVYPC 
PFCFKEFTRK DNMTAHVKII HKIENPSTAL ATVAAANLAG QPLGVSGAST PPPPDLSGQN 
SNQSLPATSN ALSTSSSSST SSSSGSLGPL TTSAPPAPAA AAQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.