Details for: ATP2A1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 22.8872
Cell Significance Index: -3.5600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 8.7919
Cell Significance Index: -2.2300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 8.5906
Cell Significance Index: -3.4900 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 7.2946
Cell Significance Index: 117.7000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 3.6554
Cell Significance Index: -3.4900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 2.8955
Cell Significance Index: -3.5700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.6083
Cell Significance Index: -3.5200 - Cell Name: secondary lymphoid organ macrophage (CL0000867)
Fold Change: 1.5993
Cell Significance Index: 11.7400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 1.4260
Cell Significance Index: -3.8200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 1.2850
Cell Significance Index: 78.7900 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.7594
Cell Significance Index: 18.5300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4798
Cell Significance Index: 95.2200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.4167
Cell Significance Index: 10.7100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3652
Cell Significance Index: 69.5100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.3381
Cell Significance Index: 21.3100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2756
Cell Significance Index: 27.2700 - Cell Name: fast muscle cell (CL0000190)
Fold Change: 0.2604
Cell Significance Index: 3.4100 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.2447
Cell Significance Index: 2.0800 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.2337
Cell Significance Index: 5.9700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2181
Cell Significance Index: 196.9700 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.2074
Cell Significance Index: 1.9100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.2012
Cell Significance Index: 5.3900 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.1774
Cell Significance Index: 2.1200 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.1749
Cell Significance Index: 2.4600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1674
Cell Significance Index: 10.8000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1399
Cell Significance Index: 22.7500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1231
Cell Significance Index: 2.1100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1211
Cell Significance Index: 13.1700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1121
Cell Significance Index: 3.2300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1108
Cell Significance Index: 8.5100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1029
Cell Significance Index: 20.6500 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.0776
Cell Significance Index: 1.1700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0737
Cell Significance Index: 9.0600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0685
Cell Significance Index: 3.1100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.0656
Cell Significance Index: 3.9400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0631
Cell Significance Index: 3.5400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0503
Cell Significance Index: 3.4800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0490
Cell Significance Index: 17.5800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0379
Cell Significance Index: 1.0600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0328
Cell Significance Index: 0.8200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0295
Cell Significance Index: 13.3700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.0231
Cell Significance Index: 1.0200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.0217
Cell Significance Index: 0.8200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0097
Cell Significance Index: 1.7500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0052
Cell Significance Index: 0.6100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0040
Cell Significance Index: 0.1400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0032
Cell Significance Index: 2.2300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0015
Cell Significance Index: 0.8100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0002
Cell Significance Index: -0.0100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0007
Cell Significance Index: -0.3200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0019
Cell Significance Index: -3.4900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0024
Cell Significance Index: -0.1500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0039
Cell Significance Index: -2.8700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0048
Cell Significance Index: -3.0200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0051
Cell Significance Index: -3.7100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0053
Cell Significance Index: -3.9800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0056
Cell Significance Index: -0.0800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0059
Cell Significance Index: -3.3100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0067
Cell Significance Index: -4.1800 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.0069
Cell Significance Index: -0.1100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0077
Cell Significance Index: -1.1200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0082
Cell Significance Index: -0.1600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0098
Cell Significance Index: -1.1600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0102
Cell Significance Index: -2.9400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0104
Cell Significance Index: -0.7000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0107
Cell Significance Index: -1.8200 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0132
Cell Significance Index: -0.5700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0157
Cell Significance Index: -0.4200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0168
Cell Significance Index: -3.5300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0180
Cell Significance Index: -2.4700 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.0193
Cell Significance Index: -0.2100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0230
Cell Significance Index: -2.3500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0250
Cell Significance Index: -2.8700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0266
Cell Significance Index: -1.3800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0282
Cell Significance Index: -3.6400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0291
Cell Significance Index: -0.6200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0293
Cell Significance Index: -2.0700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0301
Cell Significance Index: -0.6600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0307
Cell Significance Index: -0.8200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0316
Cell Significance Index: -3.2900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0333
Cell Significance Index: -0.6900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0390
Cell Significance Index: -1.8200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0440
Cell Significance Index: -2.0700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0480
Cell Significance Index: -3.8000 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0485
Cell Significance Index: -1.0300 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: -0.0486
Cell Significance Index: -0.3000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0488
Cell Significance Index: -3.6400 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.0541
Cell Significance Index: -0.8100 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0542
Cell Significance Index: -0.8000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0547
Cell Significance Index: -2.8700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0563
Cell Significance Index: -1.3500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0612
Cell Significance Index: -1.9600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0632
Cell Significance Index: -3.2900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0645
Cell Significance Index: -2.2600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0645
Cell Significance Index: -1.8400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0664
Cell Significance Index: -2.1800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0672
Cell Significance Index: -2.1400 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0753
Cell Significance Index: -0.8200 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: -0.0755
Cell Significance Index: -0.6700 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.0764
Cell Significance Index: -0.9800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 51386993
Symbol: AT2A1_HUMAN
Name: Calcium pump 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8825625
Title: Characterization of cDNA and genomic DNA encoding SERCA1, the Ca(2+)-ATPase of human fast-twitch skeletal muscle sarcoplasmic reticulum, and its elimination as a candidate gene for Brody disease.
PubMed ID: 8825625
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 28890335
Title: The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.
PubMed ID: 28890335
PubMed ID: 10914677
Title: The mutation of Pro(789) to Leu reduces the activity of the fast-twitch skeletal muscle sarco(endo)plasmic reticulum Ca(2+) ATPase (SERCA1) and is associated with Brody disease.
PubMed ID: 10914677
Sequence Information:
- Length: 1001
- Mass: 110252
- Checksum: C8F33809B56FDDEE
- Sequence:
MEAAHAKTTE ECLAYFGVSE TTGLTPDQVK RNLEKYGLNE LPAEEGKTLW ELVIEQFEDL LVRILLLAAC ISFVLAWFEE GEETITAFVE PFVILLILIA NAIVGVWQER NAENAIEALK EYEPEMGKVY RADRKSVQRI KARDIVPGDI VEVAVGDKVP ADIRILAIKS TTLRVDQSIL TGESVSVIKH TEPVPDPRAV NQDKKNMLFS GTNIAAGKAL GIVATTGVGT EIGKIRDQMA ATEQDKTPLQ QKLDEFGEQL SKVISLICVA VWLINIGHFN DPVHGGSWFR GAIYYFKIAV ALAVAAIPEG LPAVITTCLA LGTRRMAKKN AIVRSLPSVE TLGCTSVICS DKTGTLTTNQ MSVCKMFIID KVDGDICLLN EFSITGSTYA PEGEVLKNDK PVRPGQYDGL VELATICALC NDSSLDFNEA KGVYEKVGEA TETALTTLVE KMNVFNTDVR SLSKVERANA CNSVIRQLMK KEFTLEFSRD RKSMSVYCSP AKSSRAAVGN KMFVKGAPEG VIDRCNYVRV GTTRVPLTGP VKEKIMAVIK EWGTGRDTLR CLALATRDTP PKREEMVLDD SARFLEYETD LTFVGVVGML DPPRKEVTGS IQLCRDAGIR VIMITGDNKG TAIAICRRIG IFGENEEVAD RAYTGREFDD LPLAEQREAC RRACCFARVE PSHKSKIVEY LQSYDEITAM TGDGVNDAPA LKKAEIGIAM GSGTAVAKTA SEMVLADDNF STIVAAVEEG RAIYNNMKQF IRYLISSNVG EVVCIFLTAA LGLPEALIPV QLLWVNLVTD GLPATALGFN PPDLDIMDRP PRSPKEPLIS GWLFFRYMAI GGYVGAATVG AAAWWFLYAE DGPHVNYSQL THFMQCTEDN THFEGIDCEV FEAPEPMTMA LSVLVTIEMC NALNSLSENQ SLLRMPPWVN IWLLGSICLS MSLHFLILYV DPLPMIFKLR ALDLTQWLMV LKISLPVIGL DEILKFVARN YLEDPEDERR K
Genular Protein ID: 3303044892
Symbol: Q7Z675_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 994
- Mass: 109256
- Checksum: 460B75B8982246CF
- Sequence:
MEAAHAKTTE ECLAYFGVSE TTGLTPDQVK RNLEKYGLNE LPAEEGKTLW ELVIEQFEDL LVRILLLAAC ISFVLAWFEE GEETITAFVE PFVILLILIA NAIVGVWQER NAENAIEALK EYEPEMGKVY QADRKSVQRI KARDIVPGDI VEVAVGDKVP ADIRILAIKS TTLRVDQSIL TGESVSVIKH TEPVPDPRAV NQDKKNMLFS GTNIAAGKAL GIVATTGVGT EIGKIRDQMA ATEQDKTPLQ QKLDEFGEQL SKVISLICVA VWLINIGHFN DPVHGGSWFR GAIYYFKIAV ALAVAAIPEG LPAVITTCLA LGTRRMAKKN AIVRSLPSVE TLGCTSVICS DKTGTLTTNQ MSVCKMFIID KVDGDICLLN EFSITGSTYA PEGEVLKNDK PVRPGQYDGL VELATICALC NDSSLDFNEA KGVYEKVGEA TETALTTLVE KMNVFNTDVR SLSKVERANA CNSVIRQLMK KEFTLEFSRD RKSMSVYCSP AKSSRAAVGN KMFVKGAPEG VIDRCNYVRV GTTRVPLTGP VKEKIMAVIK EWGTGRDTLR CLALATRDTP PKREEMVLDD SARFLEYETD LTFVGVVGML DPPRKEVTGS IQLCRDAGIR VIMITGDNKG TAIAICRRIG IFGENEEVAD RAYTGREFDD LPLAEQREAC RRACCFARVE PSHKSKIVEY LQSYDEITAM TGDGVNDAPA LKKAEIGIAM GSGTAVAKTA SEMVLADDNF STIVAAVEEG RAIYNNMKQF IRYLISSNVG EVVCIFLTAA LGLPEALIPV QLLWVNLVTD GLPATALGFN PPDLDIMDRP PRSPEEPLIS GWLFFRYMAI GGYVGAATVG AAAWWFLYAE DGPHVNYSQL THFMQCTEDN THFEGIDCEV FEAPEPMTMA LSVLVTIEMC NALNSLSENQ SLLRMPPWVN IWLLGSICLS MSLHFLILYV DPLPMIFKLR ALDLTQWLMV LKISLPVIGL DEILKFVARN YLEG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.