Details for: ATP2A3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 58.3753
Cell Significance Index: -9.0800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 26.8549
Cell Significance Index: -10.9100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 26.2573
Cell Significance Index: -6.6600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 23.9120
Cell Significance Index: -12.3000 - Cell Name: epithelial cell of sweat gland (CL1000448)
Fold Change: 19.8835
Cell Significance Index: 14.2100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 11.8566
Cell Significance Index: -11.3200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 7.4699
Cell Significance Index: -9.2100 - Cell Name: centroblast (CL0009112)
Fold Change: 6.7379
Cell Significance Index: 15.7200 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 4.2090
Cell Significance Index: 42.4600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 3.1133
Cell Significance Index: -8.3400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.9791
Cell Significance Index: -6.5200 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 2.7609
Cell Significance Index: -8.4800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.8458
Cell Significance Index: 217.6800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.7163
Cell Significance Index: 279.1500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.6546
Cell Significance Index: 179.9800 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: 1.3627
Cell Significance Index: 28.4200 - Cell Name: early promyelocyte (CL0002154)
Fold Change: 1.2971
Cell Significance Index: 8.2800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.2564
Cell Significance Index: 81.0600 - Cell Name: megakaryocyte progenitor cell (CL0000553)
Fold Change: 1.2339
Cell Significance Index: 8.8700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.2150
Cell Significance Index: 56.6500 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: 1.1592
Cell Significance Index: 11.6000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.0511
Cell Significance Index: 63.1000 - Cell Name: salivary gland glandular cell (CL1001596)
Fold Change: 0.9091
Cell Significance Index: 5.0600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.8854
Cell Significance Index: 61.2300 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 0.8847
Cell Significance Index: 2.3700 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 0.8721
Cell Significance Index: 3.9000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.8593
Cell Significance Index: 38.9500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.8213
Cell Significance Index: 21.9700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.7898
Cell Significance Index: 17.1100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.7472
Cell Significance Index: 38.9200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5458
Cell Significance Index: 53.9900 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.5359
Cell Significance Index: 8.0300 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.5143
Cell Significance Index: 7.7500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.4607
Cell Significance Index: 13.5300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3373
Cell Significance Index: 64.1900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.3167
Cell Significance Index: 11.1300 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.3105
Cell Significance Index: 2.0600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.2924
Cell Significance Index: 550.4800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.2428
Cell Significance Index: 25.2800 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.1679
Cell Significance Index: 1.8200 - Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
Fold Change: 0.1123
Cell Significance Index: 0.7500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1025
Cell Significance Index: 17.5100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0957
Cell Significance Index: 43.4500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0902
Cell Significance Index: 2.6000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0716
Cell Significance Index: 8.8100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0590
Cell Significance Index: 1.8900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.0497
Cell Significance Index: 0.5200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.0365
Cell Significance Index: 0.8000 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.0287
Cell Significance Index: 0.5300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0267
Cell Significance Index: 14.5900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0248
Cell Significance Index: 4.9300 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 0.0170
Cell Significance Index: 0.1700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0155
Cell Significance Index: 9.8500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0118
Cell Significance Index: 21.8400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0100
Cell Significance Index: 1.8100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0033
Cell Significance Index: 0.4800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.0009
Cell Significance Index: 0.6800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0038
Cell Significance Index: -5.8300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0041
Cell Significance Index: -2.3200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0046
Cell Significance Index: -0.9300 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.0051
Cell Significance Index: -0.0600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0055
Cell Significance Index: -3.4100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0055
Cell Significance Index: -7.4800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0088
Cell Significance Index: -2.5200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0100
Cell Significance Index: -3.5800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0110
Cell Significance Index: -8.3000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0124
Cell Significance Index: -2.6100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0151
Cell Significance Index: -1.7200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0158
Cell Significance Index: -11.6200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0168
Cell Significance Index: -7.4100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0202
Cell Significance Index: -0.4300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0262
Cell Significance Index: -3.3900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0309
Cell Significance Index: -3.6000 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0321
Cell Significance Index: -0.8200 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0349
Cell Significance Index: -4.4800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0398
Cell Significance Index: -1.0000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0489
Cell Significance Index: -5.6000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0567
Cell Significance Index: -7.7800 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: -0.0761
Cell Significance Index: -0.8100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0885
Cell Significance Index: -4.1600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0945
Cell Significance Index: -9.6500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1014
Cell Significance Index: -7.7800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1056
Cell Significance Index: -1.8100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1080
Cell Significance Index: -8.0500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1135
Cell Significance Index: -3.0900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1219
Cell Significance Index: -6.3300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1241
Cell Significance Index: -8.7800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1250
Cell Significance Index: -3.3500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1269
Cell Significance Index: -1.8200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1408
Cell Significance Index: -9.4700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1463
Cell Significance Index: -8.9900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1516
Cell Significance Index: -12.0100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1530
Cell Significance Index: -9.3800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1541
Cell Significance Index: -8.0900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1547
Cell Significance Index: -9.7500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1607
Cell Significance Index: -4.4900 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: -0.1630
Cell Significance Index: -1.6900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1641
Cell Significance Index: -9.2100 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: -0.1689
Cell Significance Index: -1.0200 - Cell Name: mature T cell (CL0002419)
Fold Change: -0.1779
Cell Significance Index: -1.2800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2932677367
Symbol: AT2A3_HUMAN
Name: Calcium pump 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8809064
Title: cDNA cloning, expression and chromosomal localization of the human sarco/endoplasmic reticulum Ca(2+)-ATPase 3 gene.
PubMed ID: 8809064
DOI: 10.1042/bj3180689
PubMed ID: 9593748
Title: Structure of the human sarco/endoplasmic reticulum Ca2+-ATPase 3 gene. Promoter analysis and alternative splicing of the SERCA3 pre-mRNA.
PubMed ID: 9593748
PubMed ID: 9843705
Title: Functional characterization of alternatively spliced human SERCA3 transcripts.
PubMed ID: 9843705
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12665801
Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
PubMed ID: 12665801
DOI: 10.1038/nbt810
PubMed ID: 8288608
Title: A sarco/endoplasmic reticulum Ca(2+)-ATPase 3-type Ca2+ pump is expressed in platelets, in lymphoid cells, and in mast cells.
PubMed ID: 8288608
PubMed ID: 11956212
Title: Three novel sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) 3 isoforms. Expression, regulation, and function of the membranes of the SERCA3 family.
PubMed ID: 11956212
PubMed ID: 15028735
Title: Identification, expression, function, and localization of a novel (sixth) isoform of the human sarco/endoplasmic reticulum Ca2+ATPase 3 gene.
PubMed ID: 15028735
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 28890335
Title: The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.
PubMed ID: 28890335
PubMed ID: 34513312
Title: A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic beta cells.
PubMed ID: 34513312
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 999
- Mass: 109256
- Checksum: 44E9F1FBF41FE36A
- Sequence:
MEAAHLLPAA DVLRHFSVTA EGGLSPAQVT GARERYGPNE LPSEEGKSLW ELVLEQFEDL LVRILLLAAL VSFVLAWFEE GEETTTAFVE PLVIMLILVA NAIVGVWQER NAESAIEALK EYEPEMGKVI RSDRKGVQRI RARDIVPGDI VEVAVGDKVP ADLRLIEIKS TTLRVDQSIL TGESVSVTKH TEAIPDPRAV NQDKKNMLFS GTNITSGKAV GVAVATGLHT ELGKIRSQMA AVEPERTPLQ RKLDEFGRQL SHAISVICVA VWVINIGHFA DPAHGGSWLR GAVYYFKIAV ALAVAAIPEG LPAVITTCLA LGTRRMARKN AIVRSLPSVE TLGCTSVICS DKTGTLTTNQ MSVCRMFVVA EADAGSCLLH EFTISGTTYT PEGEVRQGDQ PVRCGQFDGL VELATICALC NDSALDYNEA KGVYEKVGEA TETALTCLVE KMNVFDTDLQ ALSRVERAGA CNTVIKQLMR KEFTLEFSRD RKSMSVYCTP TRPHPTGQGS KMFVKGAPES VIERCSSVRV GSRTAPLTPT SREQILAKIR DWGSGSDTLR CLALATRDAP PRKEDMELDD CSKFVQYETD LTFVGCVGML DPPRPEVAAC ITRCYQAGIR VVMITGDNKG TAVAICRRLG IFGDTEDVAG KAYTGREFDD LSPEQQRQAC RTARCFARVE PAHKSRIVEN LQSFNEITAM TGDGVNDAPA LKKAEIGIAM GSGTAVAKSA AEMVLSDDNF ASIVAAVEEG RAIYSNMKQF IRYLISSNVG EVVCIFLTAI LGLPEALIPV QLLWVNLVTD GLPATALGFN PPDLDIMEKL PRSPREALIS GWLFFRYLAI GVYVGLATVA AATWWFVYDA EGPHINFYQL RNFLKCSEDN PLFAGIDCEV FESRFPTTMA LSVLVTIEMC NALNSVSENQ SLLRMPPWMN PWLLVAVAMS MALHFLILLV PPLPLIFQVT PLSGRQWVVV LQISLPVILL DEALKYLSRN HMHEEMSQK
Genular Protein ID: 1110399477
Symbol: A8K9K1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 998
- Mass: 109180
- Checksum: 2AC9E56F59380E6C
- Sequence:
MEAAHLLPAA DVLRHFSVTA EGGLSPAQVT GARERYGPNE LPSEEGKSLW ELVLEQFEDL LVRILLLAAL VSFVLAWFEE GEETTTAFVE PLVIMLILVA NAIVGVWQER NAESAIEALK EYEPEMGKVI RSDRKGVQRI RARDIVPGDI VEVAVGDKVP ADLRLIEIKS TTLRVDQSIL TGESVSVTKH TEAIPDPRAV NQDKKNMLFS GTNITSGKAV GVAVATGLHT ELGKIRSQMA AVEPERTPLQ RKLDEFGRQL SHAISVICVA VWVINIGHFA DPAHGGSWLR GAVYYFKIAV ALAVAAIPEG LPAVITTCLA LGTRRMARKN AIVRSLPSVE TLGCTSVICS DKTGTLTTNQ MSVCRMFVVA EADAGSCLLH EFTISGTTYT PEGEVRQGDQ PVRCGQFDGL VELATICALC NDSALDYNEA KGVYEKVGEA TETALTCLVE KMNVFDTDLQ ALSRVERAGA CNTVIKQLMR KEFTLEFSRD RKSMSVYCTP TRPHPTGQGS KMFVKGAPES VIERCSSVRV GSRTAPLTPT SREQILAKIR DWGSGSDTLR CLALATRDAP PRKEDMELDD CSKFVQYETD LTFVGCVGML DPPRPEVAAC ITRCYQAGIR VVMITGDNKG TAVAICRRLG IFGDTEDVAG KAYTGREFDD LSPEQQRQAC RTARCFARVE PAHKSRIVEN LQSFNEITAM TGDGVNDAPA LKKAEIGIAM GSGTAVAKSA AEMVLSDDNF ASIVAAVEEG RAIYSNMKQF IRYLISSNVG EVVCIFLTAI LGLPEALIPV QLLWVNLVTD GLPATALGFN PPDLDIMEKL PRSPREALIS GWLFFRYLAI GVYVGLATVA AATWWFVYDA EGPHINFYQL RNFLKCSEDN PLFAGIDREV FESRFPTTMA LSVLVTIEMC NALNSVSENQ SLLRMPPWMN PWLLVAVAMS MALHFLILLV PPLPLIFQVT PLSGRQWVVV LQISLPVILL DEALKYLSRN HMHEMSQK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.