ACR | ENSG00000100312 | NCBI 49

Details for: ACR

Gene ID: 49

Symbol: ACR

Ensembl ID: ENSG00000100312

Description: acrosin

Associated with

Acrosome reaction and sperm:oocyte membrane binding
(R-HSA-1300645)
Fertilization
(R-HSA-1187000)
Reproduction
(R-HSA-1474165)
Acrosomal matrix
(GO:0043159)
Acrosome matrix dispersal
(GO:0002077)
Acrosome reaction
(GO:0007340)
Activation of adenylate cyclase activity
(GO:0007190)
Amidase activity
(GO:0004040)
Binding of sperm to zona pellucida
(GO:0007339)
Copper ion binding
(GO:0005507)
Dna binding
(GO:0003677)
Extracellular region
(GO:0005576)
Fucose binding
(GO:0042806)
Golgi-associated vesicle
(GO:0005798)
Mannose binding
(GO:0005537)
Nucleus
(GO:0005634)
Penetration of zona pellucida
(GO:0007341)
Protease binding
(GO:0002020)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Response to steroid hormone
(GO:0048545)
Serine-type endopeptidase activity
(GO:0004252)
Serine-type peptidase activity
(GO:0008236)
Single fertilization
(GO:0007338)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Acrosin

Genular Protein ID: 2403284358

Symbol: ACRO_HUMAN

Name: Acrosin

UniProtKB Accession Codes:

P10323 Q6ICK2

Database IDs:

Citations:

PubMed ID: 2493394

Title: Primary structure of human proacrosin deduced from its cDNA sequence.

PubMed ID: 2493394

DOI: 10.1016/0014-5793(89)80549-6

PubMed ID: 2114285

Title: Nucleotide sequence and exon-intron organization of the human proacrosin gene.

PubMed ID: 2114285

DOI: 10.1111/j.1432-1033.1990.tb15564.x

PubMed ID: 2298447

Title: Molecular cloning of human preproacrosin cDNA.

PubMed ID: 2298447

DOI: 10.1007/bf00208925

PubMed ID: 1628652

Title: Molecular cloning, sequencing and restriction mapping of the genomic sequence encoding human proacrosin.

PubMed ID: 1628652

DOI: 10.1111/j.1432-1033.1992.tb17014.x

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 7521127

Title: Inhibition of acrosin by protein C inhibitor and localization of protein C inhibitor to spermatozoa.

PubMed ID: 7521127

DOI: 10.1152/ajpcell.1994.267.2.c466

PubMed ID: 11839395

Title: Evaluation of the proacrosin/acrosin system and its mechanism of activation in human sperm extracts.

PubMed ID: 11839395

DOI: 10.1016/s0165-0378(01)00080-8

Sequence Information:

Length: 421
Mass: 45847
Checksum: 7A2F7ECEC98008FA
Sequence:

MVEMLPTAIL LVLAVSVVAK DNATCDGPCG LRFRQNPQGG VRIVGGKAAQ HGAWPWMVSL 
QIFTYNSHRY HTCGGSLLNS RWVLTAAHCF VGKNNVHDWR LVFGAKEITY GNNKPVKAPL 
QERYVEKIII HEKYNSATEG NDIALVEITP PISCGRFIGP GCLPHFKAGL PRGSQSCWVA 
GWGYIEEKAP RPSSILMEAR VDLIDLDLCN STQWYNGRVQ PTNVCAGYPV GKIDTCQGDS 
GGPLMCKDSK ESAYVVVGIT SWGVGCARAK RPGIYTATWP YLNWIASKIG SNALRMIQSA 
TPPPPTTRPP PIRPPFSHPI SAHLPWYFQP PPRPLPPRPP AAQPRPPPSP PPPPPPPASP 
LPPPPPPPPP TPSSTTKLPQ GLSFAKRLQQ LIEVLKGKTY SDGKNHYDME TTELPELTST 
S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ACR

Associated with

Other Information

Primary structure of human proacrosin deduced from its cDNA sequence. PubMed ID: 2493394

Nucleotide sequence and exon-intron organization of the human proacrosin gene. PubMed ID: 2114285

Molecular cloning of human preproacrosin cDNA. PubMed ID: 2298447

Molecular cloning, sequencing and restriction mapping of the genomic sequence encoding human proacrosin. PubMed ID: 1628652

A genome annotation-driven approach to cloning the human ORFeome. PubMed ID: 15461802

Inhibition of acrosin by protein C inhibitor and localization of protein C inhibitor to spermatozoa. PubMed ID: 7521127

Evaluation of the proacrosin/acrosin system and its mechanism of activation in human sperm extracts. PubMed ID: 11839395