Details for: ATP2B1

Gene ID: 490

Symbol: ATP2B1

Ensembl ID: ENSG00000070961

Description: ATPase plasma membrane Ca2+ transporting 1

Associated with

Other Information

Genular Protein ID: 2821752575

Symbol: AT2B1_HUMAN

Name: Plasma membrane calcium pump isoform 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2844759

Title: Complete primary structure of a human plasma membrane Ca2+ pump.

PubMed ID: 2844759

DOI: 10.1016/s0021-9258(18)68198-0

PubMed ID: 8386431

Title: Molecular cloning of a plasma membrane calcium pump from human osteoblasts.

PubMed ID: 8386431

DOI: 10.1002/jbmr.5650080415

PubMed ID: 8396145

Title: Structure of the gene encoding the human plasma membrane calcium pump isoform 1.

PubMed ID: 8396145

DOI: 10.1016/s0021-9258(19)36574-3

PubMed ID: 2528729

Title: mRNAs for plasma membrane calcium pump isoforms differing in their regulatory domain are generated by alternative splicing that involves two internal donor sites in a single exon.

PubMed ID: 2528729

DOI: 10.1073/pnas.86.18.6908

PubMed ID: 1332771

Title: Study of calmodulin binding to the alternatively spliced C-terminal domain of the plasma membrane Ca2+ pump.

PubMed ID: 1332771

DOI: 10.1021/bi00162a016

PubMed ID: 8245032

Title: Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.

PubMed ID: 8245032

DOI: 10.1016/s0021-9258(19)74484-6

PubMed ID: 7989379

Title:

PubMed ID: 7989379

DOI: 10.1016/s0021-9258(18)31797-6

PubMed ID: 7694502

Title: Human and rat intestinal plasma membrane calcium pump isoforms.

PubMed ID: 7694502

DOI: 10.1152/ajpgi.1993.265.5.g917

PubMed ID: 2548572

Title: Primary structure of the cAMP-dependent phosphorylation site of the plasma membrane calcium pump.

PubMed ID: 2548572

DOI: 10.1021/bi00436a020

PubMed ID: 1827443

Title: Protein kinase C phosphorylates the carboxyl terminus of the plasma membrane Ca(2+)-ATPase from human erythrocytes.

PubMed ID: 1827443

DOI: 10.1016/s0021-9258(18)31554-0

PubMed ID: 12763866

Title: Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants.

PubMed ID: 12763866

DOI: 10.1111/j.1749-6632.2003.tb07230.x

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18029012

Title: Inhibitory interaction of the 14-3-3 proteins with ubiquitous (PMCA1) and tissue-specific (PMCA3) isoforms of the plasma membrane Ca2+ pump.

PubMed ID: 18029012

DOI: 10.1016/j.ceca.2007.09.003

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21400627

Title: Coexpression and estrogen-mediated regulation of TRPV6 and PMCA1 in the human endometrium during the menstrual cycle.

PubMed ID: 21400627

DOI: 10.1002/mrd.21303

PubMed ID: 22084111

Title: POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters.

PubMed ID: 22084111

DOI: 10.1073/pnas.1117231108

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29104511

Title: ATP2B1 gene Silencing Increases Insulin Sensitivity through Facilitating Akt Activation via the Ca2+/calmodulin Signaling Pathway and Ca2+-associated eNOS Activation in Endothelial Cells.

PubMed ID: 29104511

DOI: 10.7150/ijbs.19666

PubMed ID: 30190470

Title: Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin.

PubMed ID: 30190470

DOI: 10.1038/s41467-018-06075-7

PubMed ID: 9020386

Title: Investigation of the Met-267 Arg exchange in isoform 1 of the human plasma membrane calcium pump in patients with essential hypertension by the amplification-created restriction site technique.

PubMed ID: 9020386

DOI: 10.1007/s001090050088

PubMed ID: 35358416

Title: De novo variants in ATP2B1 lead to neurodevelopmental delay.

PubMed ID: 35358416

DOI: 10.1016/j.ajhg.2022.03.009

Sequence Information:

  • Length: 1220
  • Mass: 134685
  • Checksum: 7E75C19B1A501423
  • Sequence:
  • MGDMANNSVA YSGVKNSLKE ANHDGDFGIT LAELRALMEL RSTDALRKIQ ESYGDVYGIC 
    TKLKTSPNEG LSGNPADLER REAVFGKNFI PPKKPKTFLQ LVWEALQDVT LIILEIAAIV 
    SLGLSFYQPP EGDNALCGEV SVGEEEGEGE TGWIEGAAIL LSVVCVVLVT AFNDWSKEKQ 
    FRGLQSRIEQ EQKFTVIRGG QVIQIPVADI TVGDIAQVKY GDLLPADGIL IQGNDLKIDE 
    SSLTGESDHV KKSLDKDPLL LSGTHVMEGS GRMVVTAVGV NSQTGIIFTL LGAGGEEEEK 
    KDEKKKEKKN KKQDGAIENR NKAKAQDGAA MEMQPLKSEE GGDGDEKDKK KANLPKKEKS 
    VLQGKLTKLA VQIGKAGLLM SAITVIILVL YFVIDTFWVQ KRPWLAECTP IYIQYFVKFF 
    IIGVTVLVVA VPEGLPLAVT ISLAYSVKKM MKDNNLVRHL DACETMGNAT AICSDKTGTL 
    TMNRMTVVQA YINEKHYKKV PEPEAIPPNI LSYLVTGISV NCAYTSKILP PEKEGGLPRH 
    VGNKTECALL GLLLDLKRDY QDVRNEIPEE ALYKVYTFNS VRKSMSTVLK NSDGSYRIFS 
    KGASEIILKK CFKILSANGE AKVFRPRDRD DIVKTVIEPM ASEGLRTICL AFRDFPAGEP 
    EPEWDNENDI VTGLTCIAVV GIEDPVRPEV PDAIKKCQRA GITVRMVTGD NINTARAIAT 
    KCGILHPGED FLCLEGKDFN RRIRNEKGEI EQERIDKIWP KLRVLARSSP TDKHTLVKGI 
    IDSTVSDQRQ VVAVTGDGTN DGPALKKADV GFAMGIAGTD VAKEASDIIL TDDNFTSIVK 
    AVMWGRNVYD SISKFLQFQL TVNVVAVIVA FTGACITQDS PLKAVQMLWV NLIMDTLASL 
    ALATEPPTES LLLRKPYGRN KPLISRTMMK NILGHAFYQL VVVFTLLFAG EKFFDIDSGR 
    NAPLHAPPSE HYTIVFNTFV LMQLFNEINA RKIHGERNVF EGIFNNAIFC TIVLGTFVVQ 
    IIIVQFGGKP FSCSELSIEQ WLWSIFLGMG TLLWGQLIST IPTSRLKFLK EAGHGTQKEE 
    IPEEELAEDV EEIDHAEREL RRGQILWFRG LNRIQTQIRV VNAFRSSLYE GLEKPESRSS 
    IHNFMTHPEF RIEDSEPHIP LIDDTDAEDD APTKRNSSPP PSPNKNNNAV DSGIHLTIEM 
    NKSATSSSPG SPLHSLETSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.