Details for: ATP2B3

Gene ID: 492

Symbol: ATP2B3

Ensembl ID: ENSG00000067842

Description: ATPase plasma membrane Ca2+ transporting 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.9742
    Cell Significance Index: 27.8000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9391
    Cell Significance Index: 188.3800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5993
    Cell Significance Index: 214.9600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.5988
    Cell Significance Index: 15.7500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.5816
    Cell Significance Index: 39.1100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5510
    Cell Significance Index: 24.3700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.5155
    Cell Significance Index: 19.5200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4061
    Cell Significance Index: 21.3200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.4059
    Cell Significance Index: 59.0000
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.3868
    Cell Significance Index: 5.1600
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.3613
    Cell Significance Index: 5.2500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.2366
    Cell Significance Index: 2.9400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1972
    Cell Significance Index: 136.4100
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.1211
    Cell Significance Index: 1.5700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0708
    Cell Significance Index: 133.3900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.0699
    Cell Significance Index: 1.5100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0633
    Cell Significance Index: 3.8900
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.0460
    Cell Significance Index: 0.3800
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.0390
    Cell Significance Index: 0.9500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0133
    Cell Significance Index: 0.3200
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.0009
    Cell Significance Index: -0.0100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0022
    Cell Significance Index: -0.1000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0052
    Cell Significance Index: -9.5500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0062
    Cell Significance Index: -9.5300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0076
    Cell Significance Index: -10.3000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0080
    Cell Significance Index: -5.0700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0104
    Cell Significance Index: -7.6200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0127
    Cell Significance Index: -9.5800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0137
    Cell Significance Index: -10.1300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0153
    Cell Significance Index: -9.5800
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.0158
    Cell Significance Index: -0.1500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0170
    Cell Significance Index: -9.2800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0171
    Cell Significance Index: -9.6700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0191
    Cell Significance Index: -8.6600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0249
    Cell Significance Index: -0.5000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0309
    Cell Significance Index: -8.8900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0382
    Cell Significance Index: -0.8100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0384
    Cell Significance Index: -0.7600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0414
    Cell Significance Index: -8.2100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0468
    Cell Significance Index: -6.4300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0472
    Cell Significance Index: -9.9500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0486
    Cell Significance Index: -8.7600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0489
    Cell Significance Index: -0.5700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0563
    Cell Significance Index: -9.6100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0575
    Cell Significance Index: -1.8300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0587
    Cell Significance Index: -0.8400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0619
    Cell Significance Index: -1.0600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0663
    Cell Significance Index: -2.1700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0802
    Cell Significance Index: -1.0000
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0812
    Cell Significance Index: -0.7700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0832
    Cell Significance Index: -8.6600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0845
    Cell Significance Index: -9.6900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0891
    Cell Significance Index: -1.8600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0945
    Cell Significance Index: -9.6600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0998
    Cell Significance Index: -7.6600
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.1003
    Cell Significance Index: -1.2000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1094
    Cell Significance Index: -2.7300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1142
    Cell Significance Index: -4.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1206
    Cell Significance Index: -9.5500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1217
    Cell Significance Index: -7.4600
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.1339
    Cell Significance Index: -1.6900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1438
    Cell Significance Index: -8.0700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1533
    Cell Significance Index: -1.6700
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.1664
    Cell Significance Index: -2.1000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1795
    Cell Significance Index: -8.3700
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.1987
    Cell Significance Index: -3.9100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2010
    Cell Significance Index: -10.4700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2081
    Cell Significance Index: -7.6400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2193
    Cell Significance Index: -9.9400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2221
    Cell Significance Index: -10.4400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2268
    Cell Significance Index: -6.3400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.2518
    Cell Significance Index: -4.0400
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.2520
    Cell Significance Index: -5.0300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2565
    Cell Significance Index: -6.8500
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.2634
    Cell Significance Index: -2.0300
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.2717
    Cell Significance Index: -3.9600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.2721
    Cell Significance Index: -7.8400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2945
    Cell Significance Index: -10.2400
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.2948
    Cell Significance Index: -3.9300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3124
    Cell Significance Index: -7.8100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.3159
    Cell Significance Index: -7.8900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.3231
    Cell Significance Index: -10.2200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3336
    Cell Significance Index: -13.6700
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.3389
    Cell Significance Index: -3.5300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3458
    Cell Significance Index: -10.1900
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3471
    Cell Significance Index: -8.0200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3578
    Cell Significance Index: -9.1400
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.3619
    Cell Significance Index: -9.2200
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: -0.3628
    Cell Significance Index: -3.9000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3649
    Cell Significance Index: -10.4600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.3696
    Cell Significance Index: -7.9000
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.3730
    Cell Significance Index: -7.5900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3736
    Cell Significance Index: -7.7500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.3783
    Cell Significance Index: -9.2300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3817
    Cell Significance Index: -6.6000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.3823
    Cell Significance Index: -8.3700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4050
    Cell Significance Index: -10.4100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.4071
    Cell Significance Index: -20.5800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4362
    Cell Significance Index: -5.2000
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.4409
    Cell Significance Index: -5.9500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The ATP2B3 gene exhibits several key characteristics that underscore its significance: 1. **Calcium Transport Function:** The PMCA3 protein is a type-4 ATPase that actively pumps calcium ions out of the cytosol and across the plasma membrane, thereby regulating cytosolic calcium levels. 2. **High Affinity for Ca2+:** The ATP2B3 gene product exhibits a high affinity for calcium ions, making it an essential component in maintaining calcium homeostasis. 3. **Regulation of Neural Function:** The ATP2B3 gene plays a critical role in regulating neural function, particularly in the context of synaptic transmission and neurotransmitter release. 4. **Muscle Contraction:** The PMCA3 protein is also involved in regulating muscle contraction, as calcium ions play a crucial role in the contraction process. **Pathways and Functions:** The ATP2B3 gene is involved in various cellular pathways and functions, including: 1. **Calcium Signaling:** The ATP2B3 gene product regulates calcium signaling by controlling the influx and efflux of calcium ions across the plasma membrane. 2. **Neurotransmitter Release:** The ATP2B3 gene plays a critical role in regulating neurotransmitter release by controlling the cytosolic calcium concentration. 3. **Muscle Contraction:** The PMCA3 protein is involved in regulating muscle contraction by controlling the influx of calcium ions into the muscle cell. 4. **Cardiac Conduction:** The ATP2B3 gene product is also involved in regulating cardiac conduction by controlling the cytosolic calcium concentration. **Clinical Significance:** Dysregulation of the ATP2B3 gene has been implicated in various diseases and disorders, including: 1. **Neurodegenerative Diseases:** Mutations in the ATP2B3 gene have been associated with neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 2. **Cardiovascular Diseases:** The ATP2B3 gene product is also involved in regulating cardiac conduction, and dysregulation of the gene has been implicated in cardiovascular diseases, such as arrhythmias and cardiac arrest. 3. **Muscle Disorders:** The PMCA3 protein is also involved in regulating muscle contraction, and dysregulation of the gene has been implicated in muscle disorders, such as muscular dystrophy. In conclusion, the ATP2B3 gene plays a critical role in regulating calcium homeostasis and neural function, making it an essential component in maintaining cellular homeostasis and function. Dysregulation of the gene has been implicated in various diseases and disorders, highlighting the importance of further research into the ATP2B3 gene and its role in human disease.

Genular Protein ID: 3856988127

Symbol: AT2B3_HUMAN

Name: Plasma membrane calcium-transporting ATPase 3

UniProtKB Accession Codes:

Q16720 B7WNR8 B7WNY5 Q12995 Q16858

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 8 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 EC 1 EMBL 7 Ensembl 5 GO 20 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 2 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 8 Pumba 1 RNAct 1 Reactome 3 RefSeq 5 Rhea 2 SFLD 2 SMART 1 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8765088

Title: Primary structure of human plasma membrane Ca(2+)-ATPase isoform 3.

PubMed ID: 8765088

DOI: 10.1016/0005-2736(96)00108-3

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 8187550

Title: Localization of two genes encoding plasma membrane Ca2+ ATPases isoforms 2 (ATP2B2) and 3 (ATP2B3) to human chromosomes 3p26-->p25 and Xq28, respectively.

PubMed ID: 8187550

DOI: 10.1159/000133794

PubMed ID: 10854409

Title: Comparative genome sequence analysis of the Bpa/Str region in mouse and man.

PubMed ID: 10854409

DOI: 10.1101/gr.10.6.758

PubMed ID: 8245032

Title: Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.

PubMed ID: 8245032

DOI: 10.1016/s0021-9258(19)74484-6

PubMed ID: 7989379

Title:

PubMed ID: 7989379

DOI: 10.1016/s0021-9258(18)31797-6

PubMed ID: 12763866

Title: Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants.

PubMed ID: 12763866

DOI: 10.1111/j.1749-6632.2003.tb07230.x

PubMed ID: 18029012

Title: Inhibitory interaction of the 14-3-3 proteins with ubiquitous (PMCA1) and tissue-specific (PMCA3) isoforms of the plasma membrane Ca2+ pump.

PubMed ID: 18029012

DOI: 10.1016/j.ceca.2007.09.003

PubMed ID: 27035656

Title: Cellular Pathophysiology of an Adrenal Adenoma-Associated Mutant of the Plasma Membrane Ca(2+)-ATPase ATP2B3.

PubMed ID: 27035656

DOI: 10.1210/en.2015-2029

PubMed ID: 22912398

Title: Mutation of plasma membrane Ca2+ ATPase isoform 3 in a family with X-linked congenital cerebellar ataxia impairs Ca2+ homeostasis.

PubMed ID: 22912398

DOI: 10.1073/pnas.1207488109

PubMed ID: 25953895

Title: A Novel Mutation in Isoform 3 of the Plasma Membrane Ca2+ Pump Impairs Cellular Ca2+ Homeostasis in a Patient with Cerebellar Ataxia and Laminin Subunit 1alpha Mutations.

PubMed ID: 25953895

DOI: 10.1074/jbc.m115.656496

Sequence Information:

  • Length: 1220
  • Mass: 134197
  • Checksum: 03B2BA8A0A33B193
  • Sequence:
    • MGDMANSSIE FHPKPQQQRD VPQAGGFGCT LAELRTLMEL RGAEALQKIE EAYGDVSGLC 
RRLKTSPTEG LADNTNDLEK RRQIYGQNFI PPKQPKTFLQ LVWEALQDVT LIILEVAAIV 
SLGLSFYAPP GEESEACGNV SGGAEDEGEA EAGWIEGAAI LLSVICVVLV TAFNDWSKEK 
QFRGLQSRIE QEQKFTVIRN GQLLQVPVAA LVVGDIAQVK YGDLLPADGV LIQANDLKID 
ESSLTGESDH VRKSADKDPM LLSGTHVMEG SGRMVVTAVG VNSQTGIIFT LLGAGGEEEE 
KKDKKGKQQD GAMESSQTKA KKQDGAVAME MQPLKSAEGG EMEEREKKKA NAPKKEKSVL 
QGKLTKLAVQ IGKAGLVMSA ITVIILVLYF VIETFVVEGR TWLAECTPVY VQYFVKFFII 
GVTVLVVAVP EGLPLAVTIS LAYSVKKMMK DNNLVRHLDA CETMGNATAI CSDKTGTLTT 
NRMTVVQSYL GDTHYKEIPA PSALTPKILD LLVHAISINS AYTTKILPPE KEGALPRQVG 
NKTECALLGF VLDLKRDFQP VREQIPEDKL YKVYTFNSVR KSMSTVIRMP DGGFRLFSKG 
ASEILLKKCT NILNSNGELR GFRPRDRDDM VRKIIEPMAC DGLRTICIAY RDFSAGQEPD 
WDNENEVVGD LTCIAVVGIE DPVRPEVPEA IRKCQRAGIT VRMVTGDNIN TARAIAAKCG 
IIQPGEDFLC LEGKEFNRRI RNEKGEIEQE RLDKVWPKLR VLARSSPTDK HTLVKGIIDS 
TTGEQRQVVA VTGDGTNDGP ALKKADVGFA MGIAGTDVAK EASDIILTDD NFTSIVKAVM 
WGRNVYDSIS KFLQFQLTVN VVAVIVAFTG ACITQDSPLK AVQMLWVNLI MDTFASLALA 
TEPPTESLLL RKPYGRDKPL ISRTMMKNIL GHAVYQLAII FTLLFVGELF FDIDSGRNAP 
LHSPPSEHYT IIFNTFVMMQ LFNEINARKI HGERNVFDGI FSNPIFCTIV LGTFGIQIVI 
VQFGGKPFSC SPLSTEQWLW CLFVGVGELV WGQVIATIPT SQLKCLKEAG HGPGKDEMTD 
EELAEGEEEI DHAERELRRG QILWFRGLNR IQTQIRVVKA FRSSLYEGLE KPESKTSIHN 
FMATPEFLIN DYTHNIPLID DTDVDENEER LRAPPPPSPN QNNNAIDSGI YLTTHVTKSA 
TSSVFSSSPG SPLHSVETSL

Genular Protein ID: 2202004353

Symbol: A0A994J5M1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A994J5M1

Database IDs:

ARBA 11 CDD 1 CTD 1 ChEBI 6 EC 1 EMBL 2 Ensembl 2 GO 4 Gene3D 4 GeneTree 1 HGNC 1 InterPro 12 NCBI Taxonomy 1 NCBIfam 2 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 2 Pfam 6 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 1 RuleBase 1 SAM 2 SFLD 2 SMART 2 SMR 1 SUPFAM 4

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 1249
  • Mass: 137397
  • Checksum: 8F038D1CA64283EC
  • Sequence:
    • MGDMANSSIE FHPKPQQQRD VPQAGGFGCT LAELRTLMEL RGAEALQKIE EAYGDVSGLC 
RRLKTSPTEG LADNTNDLEK RRQIYGQNFI PPKQPKTFLQ LVWEALQDVT LIILEVAAIV 
SLGLSFYAPP GEESEACGNV SGGAEDEGEA EAGWIEGAAI LLSVICVVLV TAFNDWSKEK 
QFRGLQSRIE QEQKFTVIRN GQLLQVPVAA LVVGDIAQVK YGDLLPADGV LIQANDLKID 
ESSLTGESDH VRKSADKDPM LLSGTHVMEG SGRMVVTAVG VNSQTGIIFT LLGAGGEEEE 
KKDKKGKQQD GAMESSQTKA KKQDGAVAME MQPLKSAEGG EMEEREKKKA NAPKKEKSVL 
QGKLTKLAVQ IGKAGLVMSA ITVIILVLYF VIETFVVEGR TWLAECTPVY VQYFVKFFII 
GVTVLVVAVP EGLPLAVTIS LAYSVKKMMK DNNLVRHLDA CETMGNATAI CSDKTGTLTT 
NRMTVVQSYL GDTHYKEIPA PSALTPKILD LLVHAISINS AYTTKILPPE KEGALPRQVG 
NKTECALLGF VLDLKRDFQP VREQIPEDKL YKVYTFNSVR KSMSTVIRMP DGGFRLFSKG 
ASEILLKKCT NILNSNGELR GFRPRDRDDM VRKIIEPMAC DGLRTICIAY RDFSAGQEPD 
WDNENEVVGD LTCIAVVGIE DPVRPEVPEA IRKCQRAGIT VRMVTGDNIN TARAIAAKCG 
IIQPGEDFLC LEGKEFNRRI RNEKGEIEQE RLDKVWPKLR VLARSSPTDK HTLVKGIIDS 
TTGEQRQVVA VTGDGTNDGP ALKKADVGFA MGIAGTDVAK EASDIILTDD NFTSIVKAVM 
WGRNVYDSIS KFLQFQLTVN VVAVIVAFTG ACITQDSPLK AVQMLWVNLI MDTFASLALA 
TEPPTESLLL RKPYGRDKPL ISRTMMKNIL GHAVYQLAII FTLLFVGELF FDIDSGRNAP 
LHSPPSEHYT IIFNTFVMMQ LFNEINARKI HGERNVFDGI FSNPIFCTIV LGTFGIQIVI 
VQFGGKPFSC SPLSTEQWLW CLFVGVGELV WGQVIATIPT SQLKCLKEAG HGPGKDEMTD 
EELAEGEEEI DHAERELRRG QILWFRGLNR IQTQMEVVST FKRSGSVQGA VRRRSSVLSQ 
LHDIRVVKAF RSSLYEGLEK PESKTSIHNF MATPEFLIND YTHNIPLIDD TDVDENEERL 
RAPPPPSPNQ NNNAIDSGIY LTTHVTKSAT SSVFSSSPGS PLHSVETSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.