Details for: ATP2B4
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 411.4559
Cell Significance Index: -64.0000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 252.6382
Cell Significance Index: -64.0800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 138.4651
Cell Significance Index: -65.3700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 130.1146
Cell Significance Index: -52.8600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 118.4326
Cell Significance Index: -60.9200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 55.3657
Cell Significance Index: -52.8600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 53.9233
Cell Significance Index: -66.4900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 22.8287
Cell Significance Index: -61.1600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 19.1905
Cell Significance Index: -42.0000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 18.8087
Cell Significance Index: -57.7700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 17.0918
Cell Significance Index: -67.4500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 3.4769
Cell Significance Index: 405.1900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 3.1300
Cell Significance Index: 240.2000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.4306
Cell Significance Index: 64.9000 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.7943
Cell Significance Index: 35.0200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.4682
Cell Significance Index: 98.7200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.3739
Cell Significance Index: 275.6100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.3130
Cell Significance Index: 129.8800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.2914
Cell Significance Index: 463.1900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.2541
Cell Significance Index: 1132.3200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.2409
Cell Significance Index: 16.9300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.1722
Cell Significance Index: 31.4100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.1145
Cell Significance Index: 62.5400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.1070
Cell Significance Index: 180.0500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.0495
Cell Significance Index: 72.5800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.9385
Cell Significance Index: 186.2500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.8098
Cell Significance Index: 22.6300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.7702
Cell Significance Index: 47.3400 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.7061
Cell Significance Index: 10.1600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.5868
Cell Significance Index: 80.5900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4651
Cell Significance Index: 253.9900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.4464
Cell Significance Index: 54.8900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4119
Cell Significance Index: 44.8100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.4005
Cell Significance Index: 177.0900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.3471
Cell Significance Index: 653.5300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.2310
Cell Significance Index: 3.4100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2251
Cell Significance Index: 155.6600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.2081
Cell Significance Index: 94.4400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1957
Cell Significance Index: 35.2700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1773
Cell Significance Index: 33.7400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0972
Cell Significance Index: 179.3300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0736
Cell Significance Index: 2.1200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0598
Cell Significance Index: 7.6700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0551
Cell Significance Index: 34.9700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0477
Cell Significance Index: 73.4800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0005
Cell Significance Index: 0.0100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0186
Cell Significance Index: -25.2900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0265
Cell Significance Index: -16.5200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0273
Cell Significance Index: -0.9600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0276
Cell Significance Index: -4.0100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0454
Cell Significance Index: -34.3400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0535
Cell Significance Index: -39.6300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0690
Cell Significance Index: -50.5700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0961
Cell Significance Index: -54.1700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1019
Cell Significance Index: -4.6200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1237
Cell Significance Index: -3.5300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1304
Cell Significance Index: -22.2600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1363
Cell Significance Index: -8.8000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1612
Cell Significance Index: -8.4000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2022
Cell Significance Index: -58.1700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2162
Cell Significance Index: -45.5300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2452
Cell Significance Index: -17.3400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.3390
Cell Significance Index: -5.8100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3404
Cell Significance Index: -8.7500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3651
Cell Significance Index: -37.3000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3681
Cell Significance Index: -38.3300 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.3762
Cell Significance Index: -5.2600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3792
Cell Significance Index: -48.9900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4419
Cell Significance Index: -50.6300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.4816
Cell Significance Index: -56.7900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4817
Cell Significance Index: -54.9800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.5153
Cell Significance Index: -26.7700 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.5489
Cell Significance Index: -16.1200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.5749
Cell Significance Index: -42.8500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.6291
Cell Significance Index: -29.3300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.6726
Cell Significance Index: -31.6100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.7258
Cell Significance Index: -57.4800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.7518
Cell Significance Index: -21.5500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.8944
Cell Significance Index: -21.4500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.9256
Cell Significance Index: -29.6500 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.9580
Cell Significance Index: -14.1400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.0140
Cell Significance Index: -16.9700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.0504
Cell Significance Index: -64.4000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -1.0708
Cell Significance Index: -67.4900 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -1.1029
Cell Significance Index: -15.4700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.1741
Cell Significance Index: -38.4400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.2660
Cell Significance Index: -40.3200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -1.2671
Cell Significance Index: -66.5300 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -1.3234
Cell Significance Index: -16.9700 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -1.3543
Cell Significance Index: -22.8100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.3557
Cell Significance Index: -59.9700 - Cell Name: helper T cell (CL0000912)
Fold Change: -1.4075
Cell Significance Index: -20.0000 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -1.4453
Cell Significance Index: -24.9900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -1.4481
Cell Significance Index: -30.8400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.4482
Cell Significance Index: -36.2000 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -1.4549
Cell Significance Index: -18.3200 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -1.4592
Cell Significance Index: -31.1900 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -1.4626
Cell Significance Index: -20.8200 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: -1.4633
Cell Significance Index: -6.3700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.5038
Cell Significance Index: -52.6800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2807099904
Symbol: AT2B4_HUMAN
Name: Matrix-remodeling-associated protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2137451
Title: Peptide sequence analysis and molecular cloning reveal two calcium pump isoforms in the human erythrocyte membrane.
PubMed ID: 2137451
PubMed ID: 1531651
Title: Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and characterization of an alternately spliced form of PMCA4 at the cDNA and genomic levels.
PubMed ID: 1531651
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8700162
Title: Analysis of mRNA expression and cloning of a novel plasma membrane Ca(2+)-ATPase splice variant in human heart.
PubMed ID: 8700162
DOI: 10.1007/bf00229314
PubMed ID: 2963820
Title: Identification and primary structure of a calmodulin binding domain of the Ca2+ pump of human erythrocytes.
PubMed ID: 2963820
PubMed ID: 2966397
Title: A C-terminal, calmodulin-like regulatory domain from the plasma membrane Ca2+-pumping ATPase.
PubMed ID: 2966397
PubMed ID: 8245032
Title: Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.
PubMed ID: 8245032
PubMed ID: 7989379
PubMed ID: 8530416
Title: Mutants in the putative nucleotide-binding region of the plasma membrane Ca(2+)-pump. A reduction in activity due to slow dephosphorylation.
PubMed ID: 8530416
PubMed ID: 12763866
Title: Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants.
PubMed ID: 12763866
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22084111
Title: POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters.
PubMed ID: 22084111
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 10493800
Title: NMR solution structure of a complex of calmodulin with a binding peptide of the Ca(2+) pump.
PubMed ID: 10493800
DOI: 10.1021/bi9908235
Sequence Information:
- Length: 1241
- Mass: 137920
- Checksum: 568544103CD5F494
- Sequence:
MTNPSDRVLP ANSMAESREG DFGCTVMELR KLMELRSRDA LTQINVHYGG VQNLCSRLKT SPVEGLSGNP ADLEKRRQVF GHNVIPPKKP KTFLELVWEA LQDVTLIILE IAAIISLVLS FYRPAGEENE LCGQVATTPE DENEAQAGWI EGAAILFSVI IVVLVTAFND WSKEKQFRGL QCRIEQEQKF SIIRNGQLIQ LPVAEIVVGD IAQVKYGDLL PADGILIQGN DLKIDESSLT GESDHVKKSL DKDPMLLSGT HVMEGSGRMV VTAVGVNSQT GIILTLLGVN EDDEGEKKKK GKKQGVPENR NKAKTQDGVA LEIQPLNSQE GIDNEEKDKK AVKVPKKEKS VLQGKLTRLA VQIGKAGLLM SALTVFILIL YFVIDNFVIN RRPWLPECTP IYIQYFVKFF IIGITVLVVA VPEGLPLAVT ISLAYSVKKM MKDNNLVRHL DACETMGNAT AICSDKTGTL TMNRMTVVQA YIGGIHYRQI PSPDVFLPKV LDLIVNGISI NSAYTSKILP PEKEGGLPRQ VGNKTECALL GFVTDLKQDY QAVRNEVPEE KLYKVYTFNS VRKSMSTVIR NPNGGFRMYS KGASEIILRK CNRILDRKGE AVPFKNKDRD DMVRTVIEPM ACDGLRTICI AYRDFDDTEP SWDNENEILT ELTCIAVVGI EDPVRPEVPD AIAKCKQAGI TVRMVTGDNI NTARAIATKC GILTPGDDFL CLEGKEFNRL IRNEKGEVEQ EKLDKIWPKL RVLARSSPTD KHTLVKGIID STVGEHRQVV AVTGDGTNDG PALKKADVGF AMGIAGTDVA KEASDIILTD DNFTSIVKAV MWGRNVYDSI SKFLQFQLTV NVVAVIVAFT GACITQDSPL KAVQMLWVNL IMDTFASLAL ATEPPTESLL KRRPYGRNKP LISRTMMKNI LGHAFYQLIV IFILVFAGEK FFDIDSGRKA PLHSPPSQHY TIVFNTFVLM QLFNEINSRK IHGEKNVFSG IYRNIIFCSV VLGTFICQIF IVEFGGKPFS CTSLSLSQWL WCLFIGIGEL LWGQFISAIP TRSLKFLKEA GHGTTKEEIT KDAEGLDEID HAEMELRRGQ ILWFRGLNRI QTQIDVINTF QTGASFKGVL RRQNMGQHLD VKLVPSSSYI KVVKAFHSSL HESIQKPYNQ KSIHSFMTHP EFAIEEELPR TPLLDEEEEE NPDKASKFGT RVLLLDGEVT PYANTNNNAV DCNQVQLPQS DSSLQSLETS V
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.