Spn88Ea | FBgn0028984 | NCBI 49804

Details for: Spn88Ea

Gene ID: 49804

Symbol: Spn88Ea

Ensembl ID: FBgn0028984

Description: Serpin 88Ea

Associated with

Asparagine n-linked glycosylation
(R-DME-446203)
Cargo concentration in the er
(R-DME-5694530)
Class a/1 (rhodopsin-like receptors)
(R-DME-373076)
Common pathway of fibrin clot formation
(R-DME-140875)
Copii-mediated vesicle transport
(R-DME-204005)
Drug adme
(R-DME-9748784)
Er to golgi anterograde transport
(R-DME-199977)
Formation of fibrin clot (clotting cascade)
(R-DME-140877)
G alpha (i) signalling events
(R-DME-418594)
G alpha (q) signalling events
(R-DME-416476)
Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Glucocorticoid biosynthesis
(R-DME-194002)
Gpcr downstream signalling
(R-DME-388396)
Gpcr ligand binding
(R-DME-500792)
Hemostasis
(R-DME-109582)
Immune system
(R-DME-168256)
Innate immune system
(R-DME-168249)
Intrinsic pathway of fibrin clot formation
(R-DME-140837)
Membrane trafficking
(R-DME-199991)
Metabolism
(R-DME-1430728)
Metabolism of angiotensinogen to angiotensins
(R-DME-2022377)
Metabolism of lipids
(R-DME-556833)
Metabolism of proteins
(R-DME-392499)
Metabolism of steroid hormones
(R-DME-196071)
Metabolism of steroids
(R-DME-8957322)
Neutrophil degranulation
(R-DME-6798695)
Peptide hormone metabolism
(R-DME-2980736)
Peptide ligand-binding receptors
(R-DME-375276)
Platelet activation, signaling and aggregation
(R-DME-76002)
Platelet degranulation
(R-DME-114608)
Post-translational protein modification
(R-DME-597592)
Post-translational protein phosphorylation
(R-DME-8957275)
Prednisone adme
(R-DME-9757110)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-DME-381426)
Response to elevated platelet cytosolic ca2+
(R-DME-76005)
Rna polymerase ii transcription
(R-DME-73857)
Runx1 regulates transcription of genes involved in differentiation of keratinocytes
(R-DME-8939242)
Signaling by gpcr
(R-DME-372790)
Signal transduction
(R-DME-162582)
Transcriptional regulation by runx1
(R-DME-8878171)
Transport to the golgi and subsequent modification
(R-DME-948021)
Vesicle-mediated transport
(R-DME-5653656)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Imaginal disc-derived wing expansion
(GO:0048526)
Negative regulation of innate immune response
(GO:0045824)
Negative regulation of proteolysis
(GO:0045861)
Negative regulation of toll receptor ligand protein activation cascade
(GO:0160035)
Serine-type endopeptidase inhibitor activity
(GO:0004867)

Other Information

Proteins

SP88E_DROME

Genular Protein ID: 1859090620

Symbol: SP88E_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VFC2 Q9U1I4

Database IDs:

Citations:

PubMed ID: 10692585

Title: A novel Drosophila serpin that inhibits serine proteases.

PubMed ID: 10692585

DOI: 10.1016/s0014-5793(00)01224-2

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 18956323

Title: The serpin Spn5 is essential for wing expansion in Drosophila melanogaster.

PubMed ID: 18956323

DOI: 10.1387/ijdb.072419yc

PubMed ID: 19581577

Title: Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia.

PubMed ID: 19581577

DOI: 10.1073/pnas.0903134106

Sequence Information:

Length: 427
Mass: 48476
Checksum: AEEF32629F5C9D4F
Sequence:

MHILSISLMA VLPAIALAGL CGVEPDAGLL DQRLNLYKGQ QNFAVSMLNV IRQSTPNENV 
FFSPYSTYHA LLLAYFGSSG DTEKELAKVL HLDWADSKEV VRSAYILEKM NRKERQSKMP 
LEFSSADRIF FANDLHVTEC ARNRLAEEVQ QIDFKSQTEE SRKQINDWIA KQTHDQIRNM 
LSADEITPRT RLVLANAAYL KGQWLSQFKT EKTVPMPFYT SPSNYSLVSM MQQKGTFLLN 
VDEQLRAHVL QLPYRTVFES QEKEDSSPDE NSDISMVLIL PPFNSNSLED VLSRLNADSL 
DDSLKQAMPR EIEVSLPKFE FEQRLELNPI LAKMGVSKMF DESVATFDDL TSETISIGDS 
KHVAKIKVDE EGSTAAAATV LFTYRSARPV EPAKFECNHP FLFVIYDRTS RSILFTGIYR 
DPKTIKQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Spn88Ea

Associated with

Other Information

A novel Drosophila serpin that inhibits serine proteases. PubMed ID: 10692585

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

The serpin Spn5 is essential for wing expansion in Drosophila melanogaster. PubMed ID: 18956323