Txnrd1 | ENSMUSG00000020250 | NCBI 50493

Details for: Txnrd1

Gene ID: 50493

Symbol: Txnrd1

Ensembl ID: ENSMUSG00000020250

Description: thioredoxin reductase 1

Associated with

Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Interconversion of nucleotide di- and triphosphates
(R-MMU-499943)
Metabolism
(R-MMU-1430728)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Metabolism of ingested meseo2h into meseh
(R-MMU-5263617)
Metabolism of nucleotides
(R-MMU-15869)
Rna polymerase ii transcription
(R-MMU-73857)
Selenoamino acid metabolism
(R-MMU-2408522)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional regulation by tp53
(R-MMU-3700989)
Benzene-containing compound metabolic process
(GO:0042537)
Cell population proliferation
(GO:0008283)
Cell redox homeostasis
(GO:0045454)
Cellular oxidant detoxification
(GO:0098869)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Fad binding
(GO:0071949)
Fibrillar center
(GO:0001650)
Gastrulation
(GO:0007369)
Hydrogen peroxide catabolic process
(GO:0042744)
Identical protein binding
(GO:0042802)
Mercury ion binding
(GO:0045340)
Mesoderm formation
(GO:0001707)
Mitochondrion
(GO:0005739)
Nad(p)h oxidase h2o2-forming activity
(GO:0016174)
Nadph oxidation
(GO:0070995)
Nadph peroxidase activity
(GO:0050137)
Neuronal cell body
(GO:0043025)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of apoptotic process
(GO:0043065)
Response to oxidative stress
(GO:0006979)
Selenate reductase activity
(GO:0033797)
Selenocysteine metabolic process
(GO:0016259)
Thioredoxin-disulfide reductase (nadph) activity
(GO:0004791)

Other Information

Proteins

Thioredoxin reductase TR1

Genular Protein ID: 1146399440

Symbol: TRXR1_MOUSE

Name: Thioredoxin reductase TR1

UniProtKB Accession Codes:

Q9JMH6 Q3UEB7 Q3UK84 Q8CI31 Q99P49 Q9CSV5

Database IDs:

Citations:

PubMed ID: 10721726

Title: Molecular cloning of mouse thioredoxin reductases.

PubMed ID: 10721726

DOI: 10.1016/s0378-1119(99)00498-9

PubMed ID: 11060283

Title: Heterogeneity within animal thioredoxin reductases: evidence for alternative first exon splicing.

PubMed ID: 11060283

DOI: 10.1074/jbc.m004750200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11737861

Title: Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes.

PubMed ID: 11737861

DOI: 10.1186/1471-2164-2-10

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 613
Mass: 67084
Checksum: C9FD2E2E8C55118C
Sequence:

MPVDDCWLYF PASRGRTFVQ TVWVAPTCPN CCWFPGFLPP VPRPPHVPRV LLRGPRGAVL 
PASRPSKTLP SSSQTPCPTD PCICPPPSTP DSRQEKNTQS ELPNKKGQLQ KLPTMNGSKD 
PPGSYDFDLI IIGGGSGGLA AAKEAAKFDK KVLVLDFVTP TPLGTRWGLG GTCVNVGCIP 
KKLMHQAALL GQALKDSRNY GWKVEDTVKH DWEKMTESVQ SHIGSLNWGY RVALREKKVV 
YENAYGRFIG PHRIVATNNK GKEKIYSAER FLIATGERPR YLGIPGDKEY CISSDDLFSL 
PYCPGKTLVV GASYVALECA GFLAGIGLDV TVMVRSILLR GFDQDMANKI GEHMEEHGIK 
FIRQFVPTKI EQIEAGTPGR LRVTAQSTNS EETIEGEFNT VLLAVGRDSC TRTIGLETVG 
VKINEKTGKI PVTDEEQTNV PYIYAIGDIL EGKLELTPVA IQAGRLLAQR LYGGSNVKCD 
YDNVPTTVFT PLEYGCCGLS EEKAVEKFGE ENIEVYHSFF WPLEWTVPSR DNNKCYAKII 
CNLKDDERVV GFHVLGPNAG EVTQGFAAAL KCGLTKQQLD STIGIHPVCA EIFTTLSVTK 
RSGGDILQSG CUG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Txnrd1

Associated with

Other Information

Molecular cloning of mouse thioredoxin reductases. PubMed ID: 10721726

Heterogeneity within animal thioredoxin reductases: evidence for alternative first exon splicing. PubMed ID: 11060283

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes. PubMed ID: 11737861

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. PubMed ID: 15592455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337