Details for: Tmprss2

Gene ID: 50528

Symbol: Tmprss2

Ensembl ID: ENSMUSG00000000385

Description: transmembrane protease, serine 2

Associated with

Other Information

Genular Protein ID: 1952151586

Symbol: TMPS2_MOUSE

Name: Epitheliasin

UniProtKB Accession Codes:

Q9JIQ8 Q7TN04 Q9JKC4 Q9QY82

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EC 1 EMBL 5 Ensembl 1 ExpressionAtlas 1 GO 7 Gene3D 3 GeneTree 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 12 KEGG 1 MEROPS 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 6 PaxDb 1 Pfam 3 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 3 SMART 3 SMR 1 STRING 1 SUPFAM 3 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 11169526

Title: Expression of transmembrane serine protease TMPRSS2 in mouse and human tissues.

PubMed ID: 11169526

DOI: 10.1002/1096-9896(2000)9999:9999<::aid-path743>3.0.co;2-t

PubMed ID: 10683448

Title: Cloning, genomic organization, chromosomal assignment and expression of a novel mosaic serine proteinase: epitheliasin.

PubMed ID: 10683448

DOI: 10.1016/s0014-5793(00)01196-0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16428450

Title: Phenotypic analysis of mice lacking the Tmprss2-encoded protease.

PubMed ID: 16428450

DOI: 10.1128/mcb.26.3.965-975.2006

PubMed ID: 24348248

Title: Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.

PubMed ID: 24348248

DOI: 10.1371/journal.ppat.1003774

PubMed ID: 24600012

Title: The host protease TMPRSS2 plays a major role for in vivo replication of emerging H7N9 and seasonal influenza viruses.

PubMed ID: 24600012

DOI: 10.1128/jvi.03677-13

PubMed ID: 24522916

Title: TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 influenza A virus in mice.

PubMed ID: 24522916

DOI: 10.1128/jvi.03799-13

PubMed ID: 25734995

Title: TMPRSS2, a novel membrane-anchored mediator in cancer pain.

PubMed ID: 25734995

DOI: 10.1097/j.pain.0000000000000130

Sequence Information:

  • Length: 490
  • Mass: 53526
  • Checksum: 54650B028417665A
  • Sequence:
    • MALNSGSPPG IGPCYENHGY QSEHICPPRP PVAPNGYNLY PAQYYPSPVP QYAPRITTQA 
STSVIHTHPK SSGALCTSKS KKSLCLALAL GTVLTGAAVA AVLLWRFWDS NCSTSEMECG 
SSGTCISSSL WCDGVAHCPN GEDENRCVRL YGQSFILQVY SSQRKAWYPV CQDDWSESYG 
RAACKDMGYK NNFYSSQGIP DQSGATSFMK LNVSSGNVDL YKKLYHSDSC SSRMVVSLRC 
IECGVRSVKR QSRIVGGLNA SPGDWPWQVS LHVQGVHVCG GSIITPEWIV TAAHCVEEPL 
SSPRYWTAFA GILRQSLMFY GSRHQVEKVI SHPNYDSKTK NNDIALMKLQ TPLAFNDLVK 
PVCLPNPGMM LDLDQECWIS GWGATYEKGK TSDVLNAAMV PLIEPSKCNS KYIYNNLITP 
AMICAGFLQG SVDSCQGDSG GPLVTLKNGI WWLIGDTSWG SGCAKALRPG VYGNVTVFTD 
WIYQQMRANS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.