Details for: Cyp4a1

Gene ID: 50549

Symbol: Cyp4a1

Ensembl ID: ENSRNOG00000009597

Description: cytochrome P450, family 4, subfamily a, polypeptide 1

Associated with

Other Information

Genular Protein ID: 2726718259

Symbol: CP4AA_RAT

Name: Cytochrome P450 4A10

UniProtKB Accession Codes:

P08516 Q5EBD8

Database IDs:

AGR 1 AlphaFoldDB 1 BRENDA 1 Bgee 1 CDD 1 CTD 1 ChEBI 74 EC 3 EMBL 4 Ensembl 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneTree 1 InParanoid 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 4 RefSeq 2 Rhea 40 SMR 1 STRING 1 SUPFAM 1 SwissLipids 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 3027069

Title: Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family.

PubMed ID: 3027069

DOI: 10.1016/s0021-9258(19)75857-8

PubMed ID: 3410047

Title: Differential splicing in the 3' non-coding region of rat cytochrome P-452 (P450 IVA1) mRNA.

PubMed ID: 3410047

DOI: 10.1016/0014-5793(88)80055-3

PubMed ID: 2766932

Title: The rat clofibrate-inducible CYP4A gene subfamily. I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization, and identification of a conserved 19-bp upstream element.

PubMed ID: 2766932

DOI: 10.1089/dna.1.1989.8.503

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1567203

Title: Characterization of a cytochrome P450 from di(2-ethylhexyl) phthalate-treated rats which hydroxylates fatty acids.

PubMed ID: 1567203

DOI: 10.1016/0003-9861(92)90714-8

PubMed ID: 10362749

Title: Kinetic profile of the rat CYP4A isoforms: arachidonic acid metabolism and isoform-specific inhibitors.

PubMed ID: 10362749

DOI: 10.1152/ajpregu.1999.276.6.r1691

PubMed ID: 10620324

Title: Structural determination of the substrate specificities and regioselectivities of the rat and human fatty acid omega-hydroxylases.

PubMed ID: 10620324

DOI: 10.1006/abbi.1999.1504

PubMed ID: 11139583

Title: Covalently linked heme in cytochrome P4504A fatty acid hydroxylases.

PubMed ID: 11139583

DOI: 10.1074/jbc.m009969200

PubMed ID: 11821421

Title: Autocatalytic mechanism and consequences of covalent heme attachment in the cytochrome P4504A family.

PubMed ID: 11821421

DOI: 10.1074/jbc.m112155200

PubMed ID: 14742258

Title: A peroxisome proliferator-activated receptor-alpha activator induces renal CYP2C23 activity and protects from angiotensin II-induced renal injury.

PubMed ID: 14742258

DOI: 10.1016/s0002-9440(10)63142-2

PubMed ID: 16212878

Title: Long-term modifications of blood pressure in normotensive and spontaneously hypertensive rats by gene delivery of rAAV-mediated cytochrome P450 arachidonic acid hydroxylase.

PubMed ID: 16212878

DOI: 10.1038/sj.cr.7290341

Sequence Information:

  • Length: 509
  • Mass: 58215
  • Checksum: E622FAB351BC40AF
  • Sequence:
    • MSVSALSSTR FTGSISGFLQ VASVLGLLLL LVKAVQFYLQ RQWLLKAFQQ FPSPPFHWFF 
GHKQFQGDKE LQQIMTCVEN FPSAFPRWFW GSKAYLIVYD PDYMKVILGR SDPKANGVYR 
LLAPWIGYGL LLLNGQPWFQ HRRMLTPAFH YDILKPYVKN MADSIRLMLD KWEQLAGQDS 
SIEIFQHISL MTLDTVMKCA FSHNGSVQVD GNYKSYIQAI GNLNDLFHSR VRNIFHQNDT 
IYNFSSNGHL FNRACQLAHD HTDGVIKLRK DQLQNAGELE KVKKKRRLDF LDILLLARME 
NGDSLSDKDL RAEVDTFMFE GHDTTASGVS WIFYALATHP EHQQRCREEV QSVLGDGSSI 
TWDHLDQIPY TTMCIKEALR LYPPVPGIVR ELSTSVTFPD GRSLPKGIQV TLSIYGLHHN 
PKVWPNPEVF DPSRFAPDSP RHSHSFLPFS GGARNCIGKQ FAMSEMKVIV ALTLLRFELL 
PDPTKVPIPL PRLVLKSKNG IYLYLKKLH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.