Pde3a | ENSRNOG00000025042 | NCBI 50678

Details for: Pde3a

Gene ID: 50678

Symbol: Pde3a

Ensembl ID: ENSRNOG00000025042

Description: phosphodiesterase 3A

Associated with

G alpha (s) signalling events
(R-RNO-418555)
Gpcr downstream signalling
(R-RNO-388396)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
3',5'-cgmp-inhibited cyclic-nucleotide phosphodiesterase activity
(GO:0004119)
3',5'-cgmp-stimulated cyclic-nucleotide phosphodiesterase activity
(GO:0004118)
3',5'-cyclic-amp phosphodiesterase activity
(GO:0004115)
3',5'-cyclic-gmp phosphodiesterase activity
(GO:0047555)
3',5'-cyclic-nucleotide phosphodiesterase activity
(GO:0004114)
Apoptotic signaling pathway
(GO:0097190)
Camp-mediated signaling
(GO:0019933)
Cellular response to cgmp
(GO:0071321)
Cellular response to transforming growth factor beta stimulus
(GO:0071560)
Cgmp-mediated signaling
(GO:0019934)
Cyclic-nucleotide phosphodiesterase activity
(GO:0004112)
Cytosol
(GO:0005829)
Estrogen binding
(GO:0099130)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Negative regulation of adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0106072)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of camp/pka signal transduction
(GO:0141162)
Negative regulation of vascular permeability
(GO:0043116)
Nuclear estrogen receptor activity
(GO:0030284)
Oocyte development
(GO:0048599)
Oocyte maturation
(GO:0001556)
Positive regulation of oocyte development
(GO:0060282)
Positive regulation of vascular permeability
(GO:0043117)
Regulation of meiotic nuclear division
(GO:0040020)
Regulation of ribonuclease activity
(GO:0060700)
Response to xenobiotic stimulus
(GO:0009410)
Steroid hormone receptor signaling pathway
(GO:0043401)

Other Information

Proteins

Cyclic GMP-inhibited phosphodiesterase A

Genular Protein ID: 2283800413

Symbol: PDE3A_RAT

Name: Cyclic GMP-inhibited phosphodiesterase A

UniProtKB Accession Codes:

Q62865

Database IDs:

Citations:

PubMed ID: 9631240

Title: Expression and characterization of deletion recombinants of two cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE-3).

PubMed ID: 9631240

DOI: 10.1007/bf02737830

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 1141
Mass: 124301
Checksum: A333DFB44F6F33F3
Sequence:

MAVRGEAAQD WAKPGLRGPS PAPVARGDHR CRGGSPSSPR GSGCCWRALA LQPLRRSPQL 
SSALCAGSLS VLLALLVRLV GGEVGGELES SQEAAAEEEE EEGARGGVFP GPRGGAPGGG 
AQLSPWLQPA ALLFSLLCAF FWMGLCLLRA GVRLPLAVAL LAACCAGEAL VQLSLGVGDG 
RLLSLPAAGV LLSCLGGATW LVLRLRLGVL MVALTSALRT VALVSLERFK VAWRPYLAYL 
AAVLGLLLAR YAEQLLPQCS GPAPPRERFG SQSSARTKEE IPGWKRRRRS SSVVAGEMSG 
CGGKSHRRTS LPCIPREQLM GHSEWDHKRG SRGSQSGTSV TVDIAVMGEA HGLITDLLAD 
PSLPPNVCTS LRAVSNLLST QLTFQAIHKP RVNPTVTFSE NYTCSDSEEG LEKDKLAIPK 
RLRRSLPPGL LRRVSSTWTT TTSATGLPTL EPAPVRRDRS ASIKPHEAPS PSAVNPDSWN 
APVLMTLTKS RSFTSSYAVS AANHVKAKKQ NRPGGLDKIS PVPSPSSSPP QGSPTSSPVS 
GIASVQFPES PEVTTKRGPG SHRALTYTQS APDLSPQIPP SPVICSSCGR PYSQGNPADG 
PSERSGPAMQ KPNRTDDTSQ VTSDYETNNN SDSSDILQND EEAECQREPL RKASACGTYT 
PQTMIFLDKP ILAPEPLVMD NLDSIMDQLN TWNFPIFDLV ENIGRKCGRI LSQVSYRLFE 
DMGLFEAFKI PVREFMNYFH ALEIGYRDIP YHNRIHATDV LHAVWYLTTQ PIPGLPSVIG 
DHGSASDSDS DSGFTHGHMG YVFSKAYHVP DDKYGCLSGN IPALELMALY VAAAMHDYDH 
PGRTNAFLVA TSAPQAVLYN DRSVLENHHA AAAWNLFMSR PEYNFLVNLD HVEFKHFRFL 
VIEAILATDL KKHFDFVAKF NAKVNDDVGI DWTNENDRLL VCQMCIKLAD INGPAKCKDL 
HLRWTEGIAS EFYEQGDEEA SLGLPISPFM DRSAPQLANL QESFISHIVG PLCHSYDSAG 
LMPGKWVDDS DDSGDTDDPE EEEEEAETPH EEETCENSEA PRKKSFKRRR IYCQITQHLL 
QNHMMWKKVI EEEQCLSGTE NQAPDQAPLQ HSSEQIQAIK EEEEEKGKPR AEETLAPQPD 
L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.