Details for: Acox1

Gene ID: 50681

Symbol: Acox1

Ensembl ID: ENSRNOG00000008755

Description: acyl-CoA oxidase 1

Associated with

Other Information

Genular Protein ID: 2528100750

Symbol: ACOX1_RAT

Name: Peroxisomal fatty acyl-CoA oxidase

UniProtKB Accession Codes:

P07872 P11354

Database IDs:

AGR 1 AlphaFoldDB 1 BRENDA 1 BindingDB 1 CDD 1 CTD 1 CarbonylDB 1 ChEBI 75 ChEMBL 1 EC 1 EMBL 3 Ensembl 5 EvolutionaryTrace 1 GO 22 Gene3D 3 GeneTree 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 2 PIRSF 1 PRO 1 PaxDb 1 Pfam 4 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 3 RefSeq 1 Rhea 36 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 2 SwissLipids 1 UniPathway 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 3036800

Title: Complete nucleotide sequence of cDNA and predicted amino acid sequence of rat acyl-CoA oxidase.

PubMed ID: 3036800

DOI: 10.1016/s0021-9258(18)47539-4

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3036801

Title: Isolation and structural characterization of the rat acyl-CoA oxidase gene.

PubMed ID: 3036801

DOI: 10.1016/s0021-9258(18)47540-0

PubMed ID: 7462191

Title: Stereochemistry of dehydrogenation catalyzed by Acyl-CoA oxidase.

PubMed ID: 7462191

DOI: 10.1093/oxfordjournals.jbchem.a133118

PubMed ID: 1400324

Title: Substrate specificities of rat liver peroxisomal acyl-CoA oxidases: palmitoyl-CoA oxidase (inducible acyl-CoA oxidase), pristanoyl-CoA oxidase (non-inducible acyl-CoA oxidase), and trihydroxycoprostanoyl-CoA oxidase.

PubMed ID: 1400324

DOI: 10.1016/s0021-9258(19)88666-0

PubMed ID: 7503725

Title: Functional expression of two forms of rat acyl-CoA oxidase and their substrate specificities.

PubMed ID: 7503725

DOI: 10.1006/bbrc.1995.2801

PubMed ID: 32169171

Title: Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms.

PubMed ID: 32169171

DOI: 10.1016/j.neuron.2020.02.021

PubMed ID: 11872165

Title: Three-dimensional structure of the flavoenzyme acyl-CoA oxidase-II from rat liver, the peroxisomal counterpart of mitochondrial acyl-CoA dehydrogenase.

PubMed ID: 11872165

DOI: 10.1093/oxfordjournals.jbchem.a003111

PubMed ID: 16672280

Title: Three-dimensional structure of rat-liver acyl-CoA oxidase in complex with a fatty acid: insights into substrate-recognition and reactivity toward molecular oxygen.

PubMed ID: 16672280

DOI: 10.1093/jb/mvj088

Sequence Information:

  • Length: 661
  • Mass: 74679
  • Checksum: 24B1F10DF066C29E
  • Sequence:
    • MNPDLRKERA SATFNPELIT HILDGSPENT RRRREIENLI LNDPDFQHED YNFLTRSQRY 
EVAVKKSATM VKKMREYGIS DPEEIMWFKK LYLANFVEPV GLNYSMFIPT LLNQGTTAQQ 
EKWMRPSQEL QIIGTYAQTE MGHGTHLRGL ETTATYDPKT QEFILNSPTV TSIKWWPGGL 
GKTSNHAIVL AQLITQGECY GLHAFVVPIR EIGTHKPLPG ITVGDIGPKF GYEEMDNGYL 
KMDNYRIPRE NMLMKYAQVK PDGTYVKPLS NKLTYGTMVF VRSFLVGNAA QSLSKACTIA 
IRYSAVRRQS EIKQSEPEPQ ILDFQTQQYK LFPLLATAYA FHFVGRYMKE TYLRINESIG 
QGDLSELPEL HALTAGLKAF TTWTANAGIE ECRMACGGHG YSHSSGIPNI YVTFTPACTF 
EGENTVMMLQ TARFLMKIYD QVRSGKLVGG MVSYLNDLPS QRIQPQQVAV WPTMVDINSL 
EGLTEAYKLR AARLVEIAAK NLQTHVSHRK SKEVAWNLTS VDLVRASEAH CHYVVVKVFS 
DKLPKIQDKA VQAVLRNLCL LYSLYGISQK GGDFLEGSII TGAQLSQVNA RILELLTLIR 
PNAVALVDAF DFKDMTLGSV LGRYDGNVYE NLFEWAKKSP LNKTEVHESY HKHLKPLQSK 
L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.