Mapk3 | ENSRNOG00000053583 | NCBI 50689

Details for: Mapk3

Gene ID: 50689

Symbol: Mapk3

Ensembl ID: ENSRNOG00000053583

Description: mitogen activated protein kinase 3

Associated with

Animal organ morphogenesis
(GO:0009887)
Apoptotic process
(GO:0006915)
Arachidonate metabolic process
(GO:0019369)
Atp binding
(GO:0005524)
Bergmann glial cell differentiation
(GO:0060020)
Bmp signaling pathway
(GO:0030509)
Cardiac neural crest cell development involved in heart development
(GO:0061308)
Cartilage development
(GO:0051216)
Caveolin-mediated endocytosis
(GO:0072584)
Cellular response to amino acid starvation
(GO:0034198)
Cellular response to mechanical stimulus
(GO:0071260)
Cellular response to toxic substance
(GO:0097237)
Cellular response to tumor necrosis factor
(GO:0071356)
Cytoplasm
(GO:0005737)
Decidualization
(GO:0046697)
Dna-binding transcription factor binding
(GO:0140297)
Dna-templated transcription
(GO:0006351)
Dna damage response
(GO:0006974)
Early endosome
(GO:0005769)
Erbb2-erbb3 signaling pathway
(GO:0038133)
Erk1 and erk2 cascade
(GO:0070371)
Face development
(GO:0060324)
Golgi apparatus
(GO:0005794)
Identical protein binding
(GO:0042802)
Insulin-like growth factor receptor signaling pathway
(GO:0048009)
Insulin receptor signaling pathway
(GO:0008286)
Interleukin-1-mediated signaling pathway
(GO:0070498)
Intracellular signal transduction
(GO:0035556)
Late endosome
(GO:0005770)
Lipopolysaccharide-mediated signaling pathway
(GO:0031663)
Lung morphogenesis
(GO:0060425)
Mapk cascade
(GO:0000165)
Map kinase activity
(GO:0004707)
Mitochondrion
(GO:0005739)
Modulation of chemical synaptic transmission
(GO:0050804)
Myelination
(GO:0042552)
Negative regulation of torc1 signaling
(GO:1904262)
Neural crest cell development
(GO:0014032)
Nuclear envelope
(GO:0005635)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Outer ear morphogenesis
(GO:0042473)
Peptidyl-serine phosphorylation
(GO:0018105)
Peptidyl-tyrosine autophosphorylation
(GO:0038083)
Phosphatase binding
(GO:0019902)
Phosphorylation
(GO:0016310)
Phosphotyrosine residue binding
(GO:0001784)
Positive regulation of cyclase activity
(GO:0031281)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of macrophage chemotaxis
(GO:0010759)
Positive regulation of macrophage proliferation
(GO:0120041)
Positive regulation of telomere maintenance
(GO:0032206)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of translation
(GO:0045727)
Positive regulation of xenophagy
(GO:1904417)
Protein-containing complex assembly
(GO:0065003)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine kinase activity
(GO:0004674)
Protein serine kinase activity
(GO:0106310)
Regulation of cellular ph
(GO:0030641)
Regulation of cytoskeleton organization
(GO:0051493)
Regulation of dna-binding transcription factor activity
(GO:0051090)
Regulation of early endosome to late endosome transport
(GO:2000641)
Regulation of golgi inheritance
(GO:0090170)
Regulation of ossification
(GO:0030278)
Regulation of stress-activated mapk cascade
(GO:0032872)
Response to epidermal growth factor
(GO:0070849)
Response to exogenous dsrna
(GO:0043330)
Response to lipopolysaccharide
(GO:0032496)
Response to toxic substance
(GO:0009636)
Scaffold protein binding
(GO:0097110)
Schwann cell development
(GO:0014044)
Sensory perception of pain
(GO:0019233)
Signal transduction in response to dna damage
(GO:0042770)
Stress-activated mapk cascade
(GO:0051403)
Thymus development
(GO:0048538)
Thyroid gland development
(GO:0030878)
Trachea formation
(GO:0060440)
Xenophagy
(GO:0098792)

Other Information

Proteins

Mitogen-activated protein kinase 3

Genular Protein ID: 3273282911

Symbol: MK03_RAT

Name: Mitogen-activated protein kinase 3

UniProtKB Accession Codes:

P21708 Q4PIY8 Q62686 Q9JJ13

Database IDs:

Citations:

PubMed ID: 1327976

Title: Sequence of a rat cDNA encoding the ERK1-MAP kinase.

PubMed ID: 1327976

DOI: 10.1016/0378-1119(92)90109-3

PubMed ID: 2164259

Title: An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control.

PubMed ID: 2164259

DOI: 10.1126/science.2164259

PubMed ID: 1716439

Title: Molecular analysis of microtubule-associated protein-2 kinase cDNA from mouse and rat brain.

PubMed ID: 1716439

DOI: 10.1089/dna.1991.10.505

PubMed ID: 1846291

Title: Purification and properties of extracellular signal-regulated kinase 1, an insulin-stimulated microtubule-associated protein 2 kinase.

PubMed ID: 1846291

DOI: 10.1021/bi00215a038

PubMed ID: 10748187

Title: ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK.

PubMed ID: 10748187

DOI: 10.1074/jbc.m910060199

PubMed ID: 15923189

Title: GIT1 is a scaffold for ERK1/2 activation in focal adhesions.

PubMed ID: 15923189

DOI: 10.1074/jbc.m502271200

PubMed ID: 28550140

Title:

PubMed ID: 28550140

DOI: 10.1074/jbc.a117.910060

PubMed ID: 1712480

Title: Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation.

PubMed ID: 1712480

DOI: 10.1073/pnas.88.14.6142

PubMed ID: 7939721

Title: PHAS-I as a link between mitogen-activated protein kinase and translation initiation.

PubMed ID: 7939721

DOI: 10.1126/science.7939721

PubMed ID: 16641100

Title: Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites.

PubMed ID: 16641100

DOI: 10.1073/pnas.0600895103

PubMed ID: 19319189

Title: Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector.

PubMed ID: 19319189

DOI: 10.1371/journal.pone.0004884

PubMed ID: 16393692

Title: The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions.

PubMed ID: 16393692

DOI: 10.1080/02699050500284218

PubMed ID: 19565474

Title: The ERK signaling cascade--views from different subcellular compartments.

PubMed ID: 19565474

DOI: 10.1002/biof.52

PubMed ID: 21779493

Title: The ERK cascade: distinct functions within various subcellular organelles.

PubMed ID: 21779493

DOI: 10.1177/1947601911407328

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 24567387

Title: MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by alpha1-adrenergic receptors.

PubMed ID: 24567387

DOI: 10.1073/pnas.1315359111

Sequence Information:

Length: 380
Mass: 43081
Checksum: 49C4EA95B627237F
Sequence:

MAAAAAAPGG GGGEPRGTAG VVPVVPGEVE VVKGQPFDVG PRYTQLQYIG EGAYGMVSSA 
YDHVRKTRVA IKKISPFEHQ TYCQRTLREI QILLRFRHEN VIGIRDILRA PTLEAMRDVY 
IVQDLMETDL YKLLKSQQLS NDHICYFLYQ ILRGLKYIHS ANVLHRDLKP SNLLINTTCD 
LKICDFGLAR IADPEHDHTG FLTEYVATRW YRAPEIMLNS KGYTKSIDIW SVGCILAEML 
SNRPIFPGKH YLDQLNHILG ILGSPSQEDL NCIINMKARN YLQSLPSKTK VAWAKLFPKS 
DSKALDLLDR MLTFNPNKRI TVEEALAHPY LEQYYDPTDE PVAEEPFTFD MELDDLPKER 
LKELIFQETA RFQPGAPEAP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mapk3

Associated with

Other Information

Sequence of a rat cDNA encoding the ERK1-MAP kinase. PubMed ID: 1327976

An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control. PubMed ID: 2164259

Molecular analysis of microtubule-associated protein-2 kinase cDNA from mouse and rat brain. PubMed ID: 1716439

Purification and properties of extracellular signal-regulated kinase 1, an insulin-stimulated microtubule-associated protein 2 kinase. PubMed ID: 1846291

ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK. PubMed ID: 10748187

GIT1 is a scaffold for ERK1/2 activation in focal adhesions. PubMed ID: 15923189

PubMed ID: 28550140

Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation. PubMed ID: 1712480

PHAS-I as a link between mitogen-activated protein kinase and translation initiation. PubMed ID: 7939721

Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites. PubMed ID: 16641100

Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector. PubMed ID: 19319189

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. PubMed ID: 16393692

The ERK signaling cascade--views from different subcellular compartments. PubMed ID: 19565474

The ERK cascade: distinct functions within various subcellular organelles. PubMed ID: 21779493

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by alpha1-adrenergic receptors. PubMed ID: 24567387