Details for: Sacs

Gene ID: 50720

Symbol: Sacs

Ensembl ID: ENSMUSG00000048279

Description: sacsin

Associated with

Other Information

Genular Protein ID: 2534069758

Symbol: SACS_MOUSE

Name: Sacsin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10655055

Title: ARSACS, a spastic ataxia common in northeastern Quebec, is caused by mutations in a new gene encoding an 11.5-kb ORF.

PubMed ID: 10655055

DOI: 10.1038/72769

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15368895

Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PubMed ID: 15368895

DOI: 10.1093/dnares/11.3.205

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19208651

Title: The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1.

PubMed ID: 19208651

DOI: 10.1093/hmg/ddp067

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 4582
  • Mass: 520685
  • Checksum: 2409B6DA64905B48
  • Sequence:
  • METKFQRWVR VTVLRGCVGC RTVAVPATAT GRDLKERIFA ETSFPVAEQR LWRGDREVPD 
    WIKIGDLTSK TCHLFVNLQS KGLKGGGRFG QTTPPLVDFL KDILRRYPEG GQILKELIQN 
    AEDAGATEVK FLYDETQYGT ETLWSKDMAQ YQGSALYVYN NAVFTPEDWH GIQEIARSRK 
    KDDPLKVGRF GIGFNSVYHI TDVPCIFSGD QIGMLDPHQT LFGPHESGQC WNLKDDIKEI 
    NELPDQFAPF IGVFGSTKET FTNGSFPGTF FRFPLRLQPS QLSSNLYTKQ KVLELFDSFR 
    ADADTVLLFL KSVQAVSLHV READGTEKLV FRVTASENKA LKHERPNSIK ILGTAISNYC 
    KKIPSNSVTC VTYHINIVLE DESTKDAQKT SWLVCNSVGG RGISSKLDSL ADELKFVPII 
    GLAMPLSGKD EENGAISDFS GKAFCFLPLP PGEESRTGLP VHISGFFGLT DNRRSIKWRE 
    LDQWRDPAAL WNEYLIVNVV PKTYATLILD SIKRLETEKS SDFPLSVDTI YKLWPEASKV 
    KAHWHPVLGP LFSELFQHAV IYSIGGEWVK LEQVHFSELD GSLESTRSVL NYLQSSGKQI 
    AKVPGNLAAA VQLSAASATS SASPVRKVTP AWVRQVLRKC AHLGSAEEKL HLLEFVLSDQ 
    AYSELLGLEL LPLQSGAFVP FSSSVSDQDV VYITSEEFPR SLFPGLEARL ILENLKPHLL 
    AALKEAAQTR GRPCTQLQLL NPERFARLIK EVMNTFWPGR ELVVQWYPFS EDKRHPSLSW 
    LKMVWKNLYI HFSEDLTLFD EMPLIPRTLL NEDQTCVELI RLRIPSVVIL DDETEAQLPE 
    FLADIVQKLG GIVLKRLDTS IQHPLVKKYI HSPLPSAILQ IMEKIPLQKL CNQIASLLPT 
    HKDALRKFLA SLTDTSEKEK RIIQELTIFK RINHSSDQGI SSYTKLKGCK VLDHTAKLPT 
    DLRLSVSVID SSDEATIRLA NMLKIEKLKT TSCLKFVLKD IGNAFYTQEE VTQLMLWILE 
    NLSSLKNENS NVLDWLMPLK FIHMSQGHVV AAGDLFDPDI EVLRDLFYNE EEACFPPTIF 
    TSPDILHSLR QIGLKNESSL KEKDVVQVAR KIEALQVSSC QNQDVLMKKA KTLLLVLNKN 
    QTLLQSSEGK MALKKIKWVP ACKERPPNYP GSLVWKGDLC NLCAPPDMCD AAHAVLVGSS 
    LPLVESVHVN LEQALSIFTK PTINAVLKHF KTVVDWYTSK TFSDEDYYQF QHILLEIYGF 
    MHDHLSEGKD SFKALKFPWV WTGKNFCPLA QAVIKPTHDL DLQPYLYNVP KTMAKFHQLF 
    KACGSIEELT SDHISMVIQK VYLKSDQELS EEESKQNLHL MLNIMRWLYS NQIPASPNTP 
    VPIYHSRNPS KLVMKPIHEC CYCDIKVDDL NDLLEDSVEP IILVHEDIPM KTAEWLKVPC 
    LSTRLINPEN MGFEQSGQRE PLTVRIKNIL EEYPSVSDIF KELLQNADDA NATECSFMID 
    MRRNMDIREN LLDPGMAACH GPALWSFNNS EFSDSDFLNI TRLGESLKRG EVDKVGKFGL 
    GFNSVYHITD IPIIMSREFM IMFDPNINHI SKHIKDRSNP GIKINWSKQQ KRLRKFPNQF 
    KPFIDVFGCQ LPLAVEAPYS YNGTLFRLSF RTQQEAKVSE VSSTCYNTAD IYSLVDEFSL 
    CGHRLIIFTQ SVNSMYLKYL KIEETNPSLA QDTIIIKKKV CPSKALNAPV LSVLKEAAKL 
    MKTCSSSNKK LPTDVPKSSC ILQITVEEFH HVFRRIADLQ SPLFRGPDDD PATLFEMAKS 
    GQSKKPSDEL PQKTVDCTTW LICTCMDTGE ALKFSLNESG RRLGLVPCGA VGVLLHETQE 
    QKWTVKPHIG EVFCYLPLRI KTGLPIHING CFAVTSNRKE IWKTDTKGRW NTTFMRHVIV 
    KAYLQALSVL RDLAIGGELT DYTYYAVWPD PDLVHDDFSV ICKGFYEDIA HGKGKELTRV 
    FSDGSMWVSM KNVRFLDDSI LQRKDVGSAA FKIFLKYLKK TGSKNLCAVE LPSSVKAGFE 
    EAGCKQILLE NTFSEKQFFS EVFFPNIQEI EAELRDPLMN FVLNEKLDEF SGILRVTPCV 
    PCSLEGHPLV LPSRLIHPEG RVAKLFDTKD GRFPYGSTQD YLNPIILIKL VQLGMAKDDI 
    LWDDMLERAE SVAEINKSDH AAACLRSSIL LSLIDEKLKI KDPRAKDFAA KYQTIPFLPF 
    LTKPAGFSLE WKGNSFKPET MFAATDIYTA EYQDIVCLLQ PILNENSHSF RGCGSVSLAV 
    KEFLGLLKKP TVDLVINQLK QVAKSVDDGI TLYQENITNA CYKYLHEAVL QNEMAKATII 
    EKLKPFCFIL VENVYVESEK VSFHLNFEAA PYLYQLPNKY KNNFRELFES VGVRQSFTVE 
    DFALVLESID QERGKKQITE ENFQLCRRII SEGIWSLIRE KRQEFCEKNY GKILLPDTNL 
    LLLPAKSLCY NDCPWIKVKD STVKYCHADI PREVAVKLGA IPKRHKALER YASNICFTAL 
    GTEFGQKEKL TSRIKSILNA YPSEKEMLKE LLQNADDAKA TEICFVFDPR QHPVDRIFDD 
    KWAPLQGPAL CVYNNQPFTE DDVRGIQNLG KGTKEGNPCK TGHYGIGFNS VYHITDCPSF 
    ISGNDILGIF DPHARYAPGA TSVSPGRMFR DLDADFRTQF SDVLDLYLGN HFKLDNCTMF 
    RFPLRNAEMA QVSEISSVPS SDRMVQNLLD KLRSDGAELL MFLNHMEKIS ICEIDKATGG 
    LNVLYSVKGK ITDGDRLKRK QFHASVIDSV TKKRQLKDIP VQQITYTMDT EDSEGNLTTW 
    LICNRSGFSS MEKVSKSVIS AHKNQDITLF PRGGVAACIT HNYKKPHRAF CFLPLSLETG 
    LPFHVNGHFA LDSARRNLWR DDNGVGVRSD WNNSLMTALI APAYVELLIQ LKKRYFPGSD 
    PTLSVLQNTP IHVVKDTLKK FLSFFPVNRL DLQPDLYCLV KALYSCIHED MKRLLPVVRA 
    PNIDGSDLHS AVIITWINMS TSNKTRPFFD NLLQDELQHL KNADYNITTR KTVAENVYRL 
    KHLLLEIGFN LVYNCDETAN LYHCLVDADI PVSYVTPADV RSFLMTFSSP DTNCHIGKLP 
    CRLQQTNLKL FHSLKLLVDY CFKDAEESEF EVEGLPLLIT LDSVLQIFDG KRPKFLTTYH 
    ELIPSRKDLF MNTLYLKYSS VLLNCKVAKV FDISSFADLL SSVLPREYKT KNCAKWKDNF 
    ASESWLKNAW HFISESVSVT DDQEEPKPAF DVIVDILKDW ALLPGTKFTV STSQLVVPEG 
    DVLIPLSLMH IAVFPNAQSD KVFHALMKAG CIQLALNKIC SKDSALVPLL SCHTANIDSP 
    ASILKAVHYM VQTSTFRTEK LMENDFEALL MYFNCNLSHL MSQDDIKILK SLPCYKSISG 
    RYMSIAKFGT CYVLTKSIPS AEVEKWTQSS SSAFLEEKVH LKELYEVLGC VPVDDLEVYL 
    KHLLPKIENL SYDAKLEHLI YLKNRLASIE EPSEIKEQLF EKLESLLIIH DANNRLKQAK 
    HFYDRTVRVF EVMLPEKLFI PKEFFKKLEQ VIKPKNQAAF MTSWVEFLRN IGLKYALSQQ 
    QLLQFAKEIS VRANTENWSK ETLQSTVDIL LHHIFQERMD LLSGNFLKEL SLIPFLCPER 
    APAEYIRFHP QYQEVNGTLP LIKFNGAQVN PKFKQCDVLQ LLWTSCPILP EKATPLSIKE 
    QEGSDLAPQE QLEQVLNMLN VNLDPPLDKV INNCRNICNI TTLDEEMVKT RAKVLRSIYE 
    FLSAEKREFR FQLRGVAFVM VEDGWKLLKP EEVVINLEYE ADFKPYLYKL PLELGTFHQL 
    FKHLGTEDII STKQYVEVLS RIFKSSEGKQ LDPNEMRTVK RVVSGLFKSL QNDSVKVRSD 
    LENARDLALY LPSQDGKLVK SSILVFDDAP HYKSRIQGNI GVQMLVDLSQ CYLGKDHGFH 
    TKLIMLFPQK LRPRLLSSIL EEQLDEETPK VCQFGALCSL QGRLQLLLSS EQFITGLIRI 
    MKHENDNAFL ANEEKAIRLC KALREGLKVS CFEKLQTTLR VKGFNPIPHS RSETFAFLKR 
    FGNAVILLYI QHSDSKDINF LLALAMTLKS ATDNLISDTS YLIAMLGCND IYRISEKLDS 
    LGVKYDSSEP SKLELPMPGT PIPAEIHYTL LMDPMNVFYP GEYVGYLVDA EGGDIYGSYQ 
    PTYTYAIIVQ EVEREDADNT SFLGKIYQID IGYSEYKIVS SLDLYKFSRP DESSQNRDSA 
    PTTPTSPTEF LTPGLRSIPP LFSGKESHKS PSTKHHSPRK LKVNALPEIL KEVTSVVEQA 
    WKLPESERKK IIRRLYLKWH PDKNPENHDI ANEVFKHLQN EINRLEKQAF LDQNADRASR 
    RTFSTSASRF QSDKYSFQRF YTSWNQEATS HKSERQQQSK EKCPPSAGQT YSQRFFVPPT 
    FKSVGNPVEA RRWLRQARAN FSAARNDLHK NANEWVCFKC YLSTKLALIA ADYAVRGKSD 
    KDVKPTALAQ KIEEYSQQLE GLTNDVHTLE AYGVDSLKTR YPDLLPFPQI PNDRFTSEVA 
    MRVMECTACI IIKLENFIQQ KV

Genular Protein ID: 539937124

Symbol: A0A0R4J125_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 768
  • Mass: 85488
  • Checksum: E1437B7C3DDB7AF6
  • Sequence:
  • METEETRWVR VTVLRGCVGC RTVAVPATAT GRDLKERIFA ETSFPVAEQR LWRGDREIPD 
    WIKIGDLTSK TCHLFVNLQS KGLKGGGRFG QTTPPLVDFL KDILRRYPEG GQILKELIQN 
    AEDAGATEVK FLYDETQYGT ETLWSKDMAQ YQGSALYVYN NAVFTPEDWH GIQEIARSRK 
    KDDPLKVGRF GIGFNSVYHI TDVPCIFSGD QIGMLDPHQT LFGPHESGQC WNLKDDIKEI 
    NELPDQFAPF IGVFGSTKET FTNGSFPGTF FRFPLRLQPS QLSSNLYTKQ KVLELFDSFR 
    ADADTVLLFL KSVQAVSLHV READGTEKLV FRVTASENKA LKHERPNSIK ILGTAISNYC 
    KKIPSNSVTC VTYHINIVLE DESTKDAQKT SWLVCNSVGG RGISSKLDSL ADELKFVPII 
    GLAMPLSGKD EENGAISDFS GKAFCFLPLP PGEESRTGLP VHISGFFGLT DNRRSIKWRE 
    LDQWRDPAAL WNEYLIVNVV PKTYATLILD SIKRLETEKS SDFPLSVDTI YKLWPEASKV 
    KAHWHPVLGP LFSELFQHAV IYSIGGEWVK LEQVHFSELD GSLESTRSVL NYLQSSGKQI 
    AKVPGNLAAA VQLSAASATS SASPVRKVTP AWVRQVLRKC AHLGSAEEKL HLLEFVLSDQ 
    AYSELLGLEL LPLQSGAFVP FSSSVSDQDV VYITSEEFPR SLFPGLEARL ILENLKPHLL 
    AALKEAAQTR GYVKHDLLTT LERISLAYSG NKNSDSPSRR SPSAVTCK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.