Details for: Gne

Gene ID: 50798

Symbol: Gne

Ensembl ID: ENSMUSG00000028479

Description: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

Associated with

Other Information

Genular Protein ID: 2442949146

Symbol: GLCNE_MOUSE

Name: UDP-GlcNAc-2-epimerase/ManAc kinase

UniProtKB Accession Codes:

Q91WG8 Q8CC83 Q8CCB0 Q9Z0P6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChEBI 49 ChiTaRS 1 DNASU 1 EC 2 EMBL 5 Ensembl 1 ExpressionAtlas 1 GO 11 Gene3D 2 GeneTree 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 Rhea 4 SMR 1 STRING 1 SUPFAM 2 SwissPalm 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 10103025

Title: Tissue expression and amino acid sequence of murine UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase.

PubMed ID: 10103025

DOI: 10.1046/j.1432-1327.1999.00253.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 10745088

Title: Protein kinase C phosphorylates and regulates UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase.

PubMed ID: 10745088

DOI: 10.1016/s0014-5793(00)01331-4

PubMed ID: 11929971

Title: Sialylation is essential for early development in mice.

PubMed ID: 11929971

DOI: 10.1073/pnas.072066199

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 38237079

Title: Novel GNE missense variants impair de novo sialylation and cause defective angiogenesis in the developing brain in mice.

PubMed ID: 38237079

DOI: 10.1182/bloodadvances.2023011490

Sequence Information:

  • Length: 722
  • Mass: 79199
  • Checksum: 0DFDD681BFD17984
  • Sequence:
    • MEKNGNNRKL RVCVATCNRA DYSKLAPIMF GIKTEPAFFE LDVVVLGSHL IDDYGNTYRM 
IEQDDFDINT RLHTIVRGED EAAMVESVGL ALVKLPDVLN RLKPDIMIVH GDRFDALALA 
TSAALMNIRI LHIEGGEVSG TIDDSIRHAI TKLAHYHVCC TRSAEQHLIS MCEDHDRILL 
AGCPSYDKLL SAKNKDYMSI IRMWLGDDVK CKDYIVALQH PVTTDIKHSI KMFELTLDAL 
ISFNKRTLVL FPNIDAGSKE MVRVMRKKGI EHHPNFRAVK HVPFDQFIQL VAHAGCMIGN 
SSCGVREVGA FGTPVINLGT RQIGRETGEN VLHVRDADTQ DKILQALHLQ FGKQYPCSKI 
YGDGNAVPRI LKFLKSIDLQ EPLQKKFCFP PVKENISQDI DHILETLSAL AVDLGGTNLR 
VAIVSMKGEI VKKYTQFNPK TYEERISLIL QMCVEAAAEA VKLNCRILGV GISTGGRVNP 
QEGVVLHSTK LIQEWNSVDL RTPLSDTLHL PVWVDNDGNC AAMAERKFGQ GKGQENFVTL 
ITGTGIGGGI IHQHELIHGS SFCAAELGHL VVSLDGPDCS CGSHGCIEAY ASGMALQREA 
KKLHDEDLLL VEGMSVPKDE AVGALHLIQA AKLGNVKAQS ILRTAGTALG LGVVNILHTM 
NPSLVILSGV LASHYIHIVK DVIRQQALSS VQDVDVVVSD LVDPALLGAA SMVLDYTTRR 
IH

Genular Protein ID: 2666325756

Symbol: Q3UW64_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UW64

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 10 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 2 GO 5 Gene3D 2 GeneTree 1 InterPro 4 MGI 2 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSR 3 PRINTS 1 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 SUPFAM 2 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 17597614

Title: Prediction of three different isoforms of the human UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.

PubMed ID: 17597614

DOI: 10.1016/j.febslet.2007.06.026

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 753
  • Mass: 82890
  • Checksum: 706DF1DE3F185225
  • Sequence:
    • METHAHLHRE QSYAGPHELY FKKLSSKKKQ VMEKNGNNRK LRVCVATCNR ADYSKLAPIM 
FGIKTEPAFF ELDVVVLGSH LIDDYGNTYR MIEQDDFDIN TRLHTIVRGE DEAAMVESVG 
LALVKLPDVL NRLKPDIMIV HGDRFDALAL ATSAALMNIR ILHIEGGEVS GTIDDSIRHA 
ITKLAHYHVC CTRSAEQHLI SMCEDHDRIL LAGCPSYDKL LSAKNKDYMS IIRMWLGDDV 
KCKDYIVALQ HPVTTDIKHS IKMFELTLDA LISFNKRTLV LFPNIDAGSK EMVRVMRKKG 
IEHHPNFRAV KHVPFDQFIQ LVAHAGCMIG NSSCGVREVG AFGTPVINLG TRQIGRETGE 
NVLHVRDADT QDKILQALHL QFGKQYPCSK IYGDGNAVPR ILKFLKSIDL QEPLQKKFCF 
PPVKENISQD IDHILETLSA LAVDLGGTNL RVAIVSMKGE IVKKYTQFNP KTYEERISLI 
LQMCVEAAAE AVKLNCRILG VGISTGGRVN PQEGVVLHST KLIQEWNSVD LRTPLSDTLH 
LPVWVDNDGN CAAMAERKFG QGKGQENFVT LITGTGIGGG IIHQHELIHG SSFCAAELGH 
LVVSLDGPDC SCGSHGCIEA YASGMALQRE AKKLHDEDLL LVEGMSVPKD EAVGALHLIQ 
AAKLGNVKAQ SILRTAGTAL GLGVVNILHT MNPSLVILSG VLASHYIHIV KDVIRQQALS 
SVQDVDVVVS DLVDPALLGA ASMVLDYTTR RIH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.