Neu3 | ENSMUSG00000035239 | NCBI 50877

Details for: Neu3

Gene ID: 50877

Symbol: Neu3

Ensembl ID: ENSMUSG00000035239

Description: neuraminidase 3

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
(R-MMU-446193)
Glycosphingolipid catabolism
(R-MMU-9840310)
Glycosphingolipid metabolism
(R-MMU-1660662)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Sialic acid metabolism
(R-MMU-4085001)
Sphingolipid metabolism
(R-MMU-428157)
Synthesis of substrates in n-glycan biosythesis
(R-MMU-446219)
Alpha-sialidase activity
(GO:0016997)
Carbohydrate metabolic process
(GO:0005975)
Caveola
(GO:0005901)
Cytoplasm
(GO:0005737)
Early endosome membrane
(GO:0031901)
Exo-alpha-sialidase activity
(GO:0004308)
External side of plasma membrane
(GO:0009897)
Ganglioside catabolic process
(GO:0006689)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Negative regulation of clathrin-dependent endocytosis
(GO:1900186)
Oligosaccharide catabolic process
(GO:0009313)
Plasma membrane
(GO:0005886)
Positive regulation of epidermal growth factor receptor signaling pathway
(GO:0045742)
Recycling endosome membrane
(GO:0055038)

Other Information

Proteins

Sialidase-3

Genular Protein ID: 3431676546

Symbol: NEUR3_MOUSE

Name: Sialidase-3

UniProtKB Accession Codes:

Q9JMH7

Database IDs:

Citations:

PubMed ID: 10713120

Title: Molecular cloning of mouse ganglioside sialidase and its increased expression in Neuro2a cell differentiation.

PubMed ID: 10713120

DOI: 10.1074/jbc.275.11.8007

PubMed ID: 11696012

Title: Degradation of G(M1) and G(M2) by mammalian sialidases.

PubMed ID: 11696012

DOI: 10.1042/0264-6021:3600233

PubMed ID: 14970224

Title: The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions.

PubMed ID: 14970224

DOI: 10.1074/jbc.m400881200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 17708748

Title: Sialidase NEU3 is a peripheral membrane protein localized on the cell surface and in endosomal structures.

PubMed ID: 17708748

DOI: 10.1042/bj20070503

Sequence Information:

Length: 418
Mass: 46846
Checksum: 64853FC963FE7686
Sequence:

MEEVPPYSLS STLFQQEEQS GVTYRIPALL YLPPTHTFLA FAEKRTSVRD EDAACLVLRR 
GLMKGRSVQW GPQRLLMEAT LPGHRTMNPC PVWEKNTGRV YLFFICVRGH VTERCQIVWG 
KNAARLCFLC SEDAGCSWGE VKDLTEEVIG SEVKRWATFA VGPGHGIQLH SGRLIIPAYA 
YYVSRWFLCF ACSVKPHSLM IYSDDFGVTW HHGKFIEPQV TGECQVAEVA GTAGNPVLYC 
SARTPSRFRA EAFSTDSGGC FQKPTLNPQL HEPRTGCQGS VVSFRPLKMP NTYQDSIGKG 
APATQKCPLL DSPLEVEKGA ETPSATWLLY SHPTSKRKRI NLGIYYNRNP LEVNCWSRPW 
ILNRGPSGYS DLAVVEEQDL VACLFECGEK NEYERIDFCL FSDHEVLSCE DCTSPSSD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Neu3

Associated with

Other Information

Molecular cloning of mouse ganglioside sialidase and its increased expression in Neuro2a cell differentiation. PubMed ID: 10713120

Degradation of G(M1) and G(M2) by mammalian sialidases. PubMed ID: 11696012

The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions. PubMed ID: 14970224