Olig2 | ENSMUSG00000039830 | NCBI 50913

Details for: Olig2

Gene ID: 50913

Symbol: Olig2

Ensembl ID: ENSMUSG00000039830

Description: oligodendrocyte transcription factor 2

Associated with

Axon development
(GO:0061564)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
E-box binding
(GO:0070888)
Hmg box domain binding
(GO:0071837)
Identical protein binding
(GO:0042802)
Myelination
(GO:0042552)
Negative regulation of neuron differentiation
(GO:0045665)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nervous system development
(GO:0007399)
Neuron differentiation
(GO:0030182)
Neuron fate commitment
(GO:0048663)
Nucleus
(GO:0005634)
Oligodendrocyte differentiation
(GO:0048709)
Positive regulation of oligodendrocyte differentiation
(GO:0048714)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Regulation of dna-templated transcription
(GO:0006355)
Sensory organ development
(GO:0007423)
Sequence-specific double-stranded dna binding
(GO:1990837)
Spinal cord motor neuron differentiation
(GO:0021522)
Spinal cord oligodendrocyte cell differentiation
(GO:0021529)
Spinal cord oligodendrocyte cell fate specification
(GO:0021530)
Thalamus development
(GO:0021794)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

Oligodendrocyte transcription factor 2

Genular Protein ID: 3692018984

Symbol: OLIG2_MOUSE

Name: Oligodendrocyte transcription factor 2

UniProtKB Accession Codes:

Q9EQW6 Q9JKN4

Database IDs:

Citations:

PubMed ID: 11091082

Title: Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3.

PubMed ID: 11091082

DOI: 10.1016/s0925-4773(00)00466-4

PubMed ID: 10719889

Title: Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors.

PubMed ID: 10719889

DOI: 10.1016/s0896-6273(00)80898-3

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10719888

Title: Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system.

PubMed ID: 10719888

DOI: 10.1016/s0896-6273(00)80897-1

PubMed ID: 11955448

Title: Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.

PubMed ID: 11955448

DOI: 10.1016/s0092-8674(02)00678-5

PubMed ID: 12121626

Title: The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages.

PubMed ID: 12121626

DOI: 10.1016/s0960-9822(02)00926-0

PubMed ID: 11960707

Title: Non-overlapping expression of Olig3 and Olig2 in the embryonic neural tube.

PubMed ID: 11960707

DOI: 10.1016/s0925-4773(02)00021-7

PubMed ID: 14602683

Title: Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor.

PubMed ID: 14602683

DOI: 10.1242/dev.00868

PubMed ID: 14573534

Title: Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.

PubMed ID: 14573534

DOI: 10.1523/jneurosci.23-29-09547.2003

PubMed ID: 16908628

Title: An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation.

PubMed ID: 16908628

DOI: 10.1242/dev.02522

Sequence Information:

Length: 323
Mass: 32407
Checksum: 598AE76CB512D716
Sequence:

MDSDASLVSS RPSSPEPDDL FLPARSKGGS SSGFTGGTVS SSTPSDCPPE LSSELRGAMG 
ASGAHPGDKL GGGGFKSSSS STSSSTSSAA TSSTKKDKKQ MTEPELQQLR LKINSRERKR 
MHDLNIAMDG LREVMPYAHG PSVRKLSKIA TLLLARNYIL MLTNSLEEMK RLVSEIYGGH 
HAGFHPSACG GLAHSAPLPT ATAHPAAAAH AAHHPAVHHP ILPPAAAAAA AAAAAAAVSS 
ASLPGSGLSS VGSIRPPHGL LKSPSAAAAA PLGGGGGGSG GSGGFQHWGG MPCPCSMCQV 
PPPHHHVSAM GAGTLPRLTS DAK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Olig2

Associated with

Other Information

Dynamic expression of basic helix-loop-helix Olig family members: implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3. PubMed ID: 11091082

Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors. PubMed ID: 10719889

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. PubMed ID: 10719888

Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. PubMed ID: 11955448

The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages. PubMed ID: 12121626

Non-overlapping expression of Olig3 and Olig2 in the embryonic neural tube. PubMed ID: 11960707

Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor. PubMed ID: 14602683

Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex. PubMed ID: 14573534

An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. PubMed ID: 16908628