Details for: ACOX1

Gene ID: 51

Symbol: ACOX1

Ensembl ID: ENSG00000161533

Description: acyl-CoA oxidase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 209.2639
    Cell Significance Index: -32.5500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 127.3244
    Cell Significance Index: -32.3000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 72.5447
    Cell Significance Index: -34.2500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 68.9957
    Cell Significance Index: -28.0300
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 50.9968
    Cell Significance Index: -34.2200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 29.2330
    Cell Significance Index: -27.9100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 26.8947
    Cell Significance Index: -33.1600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.4643
    Cell Significance Index: -33.3900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.5351
    Cell Significance Index: -33.6800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.8080
    Cell Significance Index: -14.9000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 3.8984
    Cell Significance Index: 454.3100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 3.1342
    Cell Significance Index: 52.8000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.5910
    Cell Significance Index: 23.8600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.9903
    Cell Significance Index: 103.3900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.8399
    Cell Significance Index: 39.8600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.6062
    Cell Significance Index: 318.7500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.5127
    Cell Significance Index: 164.5400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.4362
    Cell Significance Index: 21.5200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.3378
    Cell Significance Index: 35.7200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.2262
    Cell Significance Index: 16.7300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9875
    Cell Significance Index: 121.4300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8964
    Cell Significance Index: 161.6000
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.8759
    Cell Significance Index: 11.0300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.8578
    Cell Significance Index: 24.7200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7670
    Cell Significance Index: 153.8500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6977
    Cell Significance Index: 630.0000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.6827
    Cell Significance Index: 48.2800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.6233
    Cell Significance Index: 15.5800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5629
    Cell Significance Index: 43.2000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4718
    Cell Significance Index: 169.2400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4470
    Cell Significance Index: 20.8400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4450
    Cell Significance Index: 20.1700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3620
    Cell Significance Index: 61.8100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3245
    Cell Significance Index: 143.4500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.2890
    Cell Significance Index: 32.9900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2767
    Cell Significance Index: 191.3900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.2758
    Cell Significance Index: 7.0900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2369
    Cell Significance Index: 6.6200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2287
    Cell Significance Index: 124.8800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2036
    Cell Significance Index: 38.7400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1954
    Cell Significance Index: 26.8400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1618
    Cell Significance Index: 10.2000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1594
    Cell Significance Index: 20.4300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1498
    Cell Significance Index: 14.8200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1204
    Cell Significance Index: 3.2200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.1176
    Cell Significance Index: 13.4800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.1023
    Cell Significance Index: 1.5100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.0558
    Cell Significance Index: 1.0900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0516
    Cell Significance Index: 32.7500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0340
    Cell Significance Index: 64.1100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0331
    Cell Significance Index: 0.9000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0296
    Cell Significance Index: 45.6400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0230
    Cell Significance Index: 42.4300
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.0046
    Cell Significance Index: 0.0200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0045
    Cell Significance Index: 2.0300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0085
    Cell Significance Index: -0.1800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0088
    Cell Significance Index: -6.4400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0099
    Cell Significance Index: -1.4400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0113
    Cell Significance Index: -8.3900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0150
    Cell Significance Index: -20.3300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0199
    Cell Significance Index: -12.4400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0227
    Cell Significance Index: -17.2000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0295
    Cell Significance Index: -1.0400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0400
    Cell Significance Index: -2.6900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0428
    Cell Significance Index: -24.1400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0520
    Cell Significance Index: -2.7100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0819
    Cell Significance Index: -8.3700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0829
    Cell Significance Index: -5.3500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0875
    Cell Significance Index: -18.4300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0940
    Cell Significance Index: -27.0500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0948
    Cell Significance Index: -5.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0955
    Cell Significance Index: -4.2300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0979
    Cell Significance Index: -6.0200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1363
    Cell Significance Index: -3.1500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1399
    Cell Significance Index: -18.0800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1400
    Cell Significance Index: -5.3000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1470
    Cell Significance Index: -17.3400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1740
    Cell Significance Index: -8.1800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1819
    Cell Significance Index: -13.5600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2679
    Cell Significance Index: -3.9600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2877
    Cell Significance Index: -9.2200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2941
    Cell Significance Index: -5.0400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2966
    Cell Significance Index: -23.4900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2976
    Cell Significance Index: -30.9900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3400
    Cell Significance Index: -8.9400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3637
    Cell Significance Index: -10.4300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.3693
    Cell Significance Index: -9.0100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4354
    Cell Significance Index: -5.1900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4493
    Cell Significance Index: -23.5900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5440
    Cell Significance Index: -33.3500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.5457
    Cell Significance Index: -4.4500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.5643
    Cell Significance Index: -10.4300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.5695
    Cell Significance Index: -5.9000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5727
    Cell Significance Index: -9.5900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5868
    Cell Significance Index: -20.3900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.6056
    Cell Significance Index: -13.2600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.6723
    Cell Significance Index: -22.0100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6801
    Cell Significance Index: -21.6600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6979
    Cell Significance Index: -24.4500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.7004
    Cell Significance Index: -20.5700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Subcellular localization:** ACOX1 is primarily located in the peroxisome, a organelle responsible for the degradation of fatty acids and amino acids. 2. **Enzymatic activity:** ACOX1 catalyzes the oxidative decarboxylation of acyl-CoA esters, producing acyl-CoA and CO2. 3. **Regulation:** ACOX1 is regulated by various factors, including transcription factors (e.g., PPARα) and protein-protein interactions (e.g., Tysnd1). 4. **Substrate specificity:** ACOX1 prefers long-chain fatty acids (C16-C22) for oxidation, while short-chain fatty acids (C4-C15) are primarily metabolized by other enzymes. **Pathways and Functions:** ACOX1 is involved in the following pathways: 1. **Fatty acid beta-oxidation:** ACOX1 plays a critical role in the breakdown of fatty acids, which provides energy for various tissues. 2. **Lipid metabolism:** ACOX1 regulates lipid metabolism by influencing the levels of acyl-CoA esters, which are involved in various biological processes, including energy storage, signaling, and membrane synthesis. 3. **Energy production:** ACOX1 contributes to the generation of precursor metabolites and energy, which is essential for maintaining cellular homeostasis. 4. **Redox balance:** ACOX1 helps maintain the redox balance by producing H2O2, which is involved in various cellular processes, including signaling and detoxification. **Clinical Significance:** Dysregulation of ACOX1 has been implicated in various diseases, including: 1. **Metabolic disorders:** ACOX1 deficiency has been linked to metabolic disorders, such as obesity, insulin resistance, and type 2 diabetes. 2. **Fatty liver disease:** ACOX1 plays a crucial role in the development of fatty liver disease, which is characterized by excessive fat accumulation in the liver. 3. **Cancer:** ACOX1 has been implicated in the progression of various cancers, including colorectal, breast, and prostate cancer. 4. **Neurological disorders:** ACOX1 has been linked to neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, ACOX1 is a vital enzyme involved in fatty acid metabolism, playing a crucial role in regulating lipid metabolism, energy production, and redox balance. Dysregulation of ACOX1 has been implicated in various diseases, highlighting the importance of this enzyme in maintaining cellular homeostasis. Further research is needed to fully understand the mechanisms of ACOX1 and its clinical implications.

Genular Protein ID: 4077081

Symbol: ACOX1_HUMAN

Name: Peroxisomal fatty acyl-CoA oxidase

UniProtKB Accession Codes:

Q15067 A8K6X8 A8KAA0 B4DK61 F5GYQ8 Q12863 Q15068 Q15101 Q16131 Q7Z3W5 Q9UD31

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 87 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 DrugCentral 1 EC 3 EMBL 38 Ensembl 2 ExpressionAtlas 1 GO 25 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PIR 3 PIRSF 1 PRIDE 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 5 RefSeq 3 Rhea 42 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 2 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8159712

Title: Isolation of the human peroxisomal acyl-CoA oxidase gene: organization, promoter analysis, and chromosomal localization.

PubMed ID: 8159712

DOI: 10.1073/pnas.91.8.3107

PubMed ID: 7876265

Title: Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells.

PubMed ID: 7876265

DOI: 10.1074/jbc.270.9.4908

PubMed ID: 8040306

Title: Large deletion of the peroxisomal acyl-CoA oxidase gene in pseudoneonatal adrenoleukodystrophy.

PubMed ID: 8040306

DOI: 10.1172/jci117365

PubMed ID: 8117268

Title: Molecular cloning and functional expression of a human peroxisomal acyl-coenzyme A oxidase.

PubMed ID: 8117268

DOI: 10.1006/bbrc.1994.1158

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15060085

Title: Identification of the peroxisomal beta-oxidation enzymes involved in the degradation of long-chain dicarboxylic acids.

PubMed ID: 15060085

DOI: 10.1194/jlr.m300512-jlr200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17603022

Title: Biochemical characterization of two functional human liver acyl-CoA oxidase isoforms 1a and 1b encoded by a single gene.

PubMed ID: 17603022

DOI: 10.1016/j.bbrc.2007.06.059

PubMed ID: 18281296

Title: Contribution of peroxisome-specific isoform of Lon protease in sorting PTS1 proteins to peroxisomes.

PubMed ID: 18281296

DOI: 10.1093/jb/mvn020

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20195242

Title: Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform.

PubMed ID: 20195242

DOI: 10.1038/labinvest.2010.46

PubMed ID: 33234382

Title: Novel ACOX1 mutations in two siblings with peroxisomal acyl-CoA oxidase deficiency.

PubMed ID: 33234382

DOI: 10.1016/j.braindev.2020.10.011

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 11815777

Title: Peroxisomal acyl-CoA oxidase deficiency.

PubMed ID: 11815777

DOI: 10.1067/mpd.2002.120511

PubMed ID: 17458872

Title: Clinical, biochemical, and mutational spectrum of peroxisomal acyl-coenzyme A oxidase deficiency.

PubMed ID: 17458872

DOI: 10.1002/humu.20535

PubMed ID: 32169171

Title: Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms.

PubMed ID: 32169171

DOI: 10.1016/j.neuron.2020.02.021

Sequence Information:

  • Length: 660
  • Mass: 74424
  • Checksum: D713768A47374EA1
  • Sequence:
    • MNPDLRRERD SASFNPELLT HILDGSPEKT RRRREIENMI LNDPDFQHED LNFLTRSQRY 
EVAVRKSAIM VKKMREFGIA DPDEIMWFKK LHLVNFVEPV GLNYSMFIPT LLNQGTTAQK 
EKWLLSSKGL QIIGTYAQTE MGHGTHLRGL ETTATYDPET QEFILNSPTV TSIKWWPGGL 
GKTSNHAIVL AQLITKGKCY GLHAFIVPIR EIGTHKPLPG ITVGDIGPKF GYDEIDNGYL 
KMDNHRIPRE NMLMKYAQVK PDGTYVKPLS NKLTYGTMVF VRSFLVGEAA RALSKACTIA 
IRYSAVRHQS EIKPGEPEPQ ILDFQTQQYK LFPLLATAYA FQFVGAYMKE TYHRINEGIG 
QGDLSELPEL HALTAGLKAF TSWTANTGIE ACRMACGGHG YSHCSGLPNI YVNFTPSCTF 
EGENTVMMLQ TARFLMKSYD QVHSGKLVCG MVSYLNDLPS QRIQPQQVAV WPTMVDINSP 
ESLTEAYKLR AARLVEIAAK NLQKEVIHRK SKEVAWNLTS VDLVRASEAH CHYVVVKLFS 
EKLLKIQDKA IQAVLRSLCL LYSLYGISQN AGDFLQGSIM TEPQITQVNQ RVKELLTLIR 
SDAVALVDAF DFQDVTLGSV LGRYDGNVYE NLFEWAKNSP LNKAEVHESY KHLKSLQSKL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.