Details for: ATP5F1E

Gene ID: 514

Symbol: ATP5F1E

Ensembl ID: ENSG00000124172

Description: ATP synthase F1 subunit epsilon

Associated with

  • Cristae formation
    (R-HSA-8949613)
  • Formation of atp by chemiosmotic coupling
    (R-HSA-163210)
  • Metabolism
    (R-HSA-1430728)
  • Mitochondrial biogenesis
    (R-HSA-1592230)
  • Organelle biogenesis and maintenance
    (R-HSA-1852241)
  • Respiratory electron transport, atp synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    (R-HSA-163200)
  • The citric acid (tca) cycle and respiratory electron transport
    (R-HSA-1428517)
  • Hydrolase activity
    (GO:0016787)
  • Mitochondrial inner membrane
    (GO:0005743)
  • Mitochondrial matrix
    (GO:0005759)
  • Mitochondrial proton-transporting atp synthase complex
    (GO:0005753)
  • Mitochondrial proton-transporting atp synthase complex, catalytic sector f(1)
    (GO:0000275)
  • Protein binding
    (GO:0005515)
  • Proton-transporting atp synthase activity, rotational mechanism
    (GO:0046933)
  • Proton motive force-driven atp synthesis
    (GO:0015986)
  • Proton motive force-driven mitochondrial atp synthesis
    (GO:0042776)
  • Proton transmembrane transport
    (GO:1902600)

Other Information

Genular Protein ID: 628744576

Symbol: ATP5E_HUMAN

Name: N/A

UniProtKB Accession Codes:

P56381 B2RDD0 E1P5H6 Q53XU6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ComplexPortal 1 DNASU 1 DisGeNET 1 EMBL 10 EMDB 1 EPD 1 Ensembl 3 GO 8 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 8 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10727396

Title: Cloning, characterization and mapping of the human ATP5E gene, identification of pseudogene ATP5EP1, and definition of the ATP5E motif.

PubMed ID: 10727396

DOI: 10.1042/bj3470017

PubMed ID: 10931946

Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.

PubMed ID: 10931946

DOI: 10.1073/pnas.160270997

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 20566710

Title: Mitochondrial ATP synthase deficiency due to a mutation in the ATP5E gene for the F1 epsilon subunit.

PubMed ID: 20566710

DOI: 10.1093/hmg/ddq254

PubMed ID: 34954817

Title: Variants in Mitochondrial ATP Synthase Cause Variable Neurologic Phenotypes.

PubMed ID: 34954817

DOI: 10.1002/ana.26293

Sequence Information:

  • Length: 51
  • Mass: 5780
  • Checksum: C3E8FDA7C9191CA4
  • Sequence:
    • MVAYWRQAGL SYIRYSQICA KAVRDALKTE FKANAEKTSG SNVKIVKVKK E

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.