Details for: ATP5PB
Gene ID: 515
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: ATP5PB
Ensembl ID: ENSG00000116459
Description: ATP synthase peripheral stalk-membrane subunit b
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
-
CSI 81.54rCSI 73.63%PRS 7.77
-
CSI 79.62rCSI 52.92%PRS 10.5
-
CSI 79.15rCSI 76.32%PRS 5.74
-
CSI 77.13rCSI 62.37%PRS 8.68
-
CSI 69.66rCSI 72.97%PRS 8.18
-
CSI 68.82rCSI 71.93%PRS 9.28
-
CSI 65.37rCSI 76.77%PRS 10.47
-
CSI 63.1rCSI 54.63%PRS 9.81
-
CSI 62.63rCSI 55.01%PRS 9.88
-
CSI 60.58rCSI 69.35%PRS 18.2
-
CSI 59.16rCSI 56.95%PRS 9.1
-
CSI 58.4rCSI 73.29%PRS 11.23
-
CSI 57.29rCSI 48.03%PRS 10.52
-
CSI 54.65rCSI 42.99%PRS 10.49
-
CSI 49.71rCSI 41.21%PRS 8.35
-
CSI 47.24rCSI 41.54%PRS 6.38
-
CSI 44.66rCSI 39.64%PRS 8.8
-
CSI 43.4rCSI 69.98%PRS 14.08
-
CSI 38.89rCSI 29.96%PRS 7.95
-
CSI 38.18rCSI 58.39%PRS 14.3
-
CSI 38.03rCSI 54.85%PRS 12.3
-
CSI 34.52rCSI 59.15%PRS 11.8
-
CSI 33.88rCSI 36%PRS 15.72
-
CSI 33.45rCSI 48.21%PRS 14.19
-
CSI 33.05rCSI 47.16%PRS 9.95
-
CSI 31.85rCSI 31.33%PRS 9.55
-
CSI 31.4rCSI 24.94%PRS 15.53
-
CSI 31.26rCSI 26.1%PRS 27.2
-
CSI 31.07rCSI 32.55%PRS 9.37
-
CSI 30.08rCSI 40.98%PRS 7.88
-
CSI 29.3rCSI 69.65%PRS 13.21
-
CSI 29.08rCSI 29.64%PRS 12.57
-
CSI 28.48rCSI 44.01%PRS 8.23
-
CSI 27.95rCSI 26.41%PRS 9.19
-
CSI 27.34rCSI 39.19%PRS 12.06
-
CSI 25.8rCSI 52.97%PRS 21.03
-
CSI 25.73rCSI 23.74%PRS 8.95
-
CSI 24.68rCSI 52.52%PRS 14.2
-
CSI 24.17rCSI 46.15%PRS 21.1
-
CSI 23.86rCSI 19.76%PRS 8.79
-
CSI 23.08rCSI 28.55%PRS 7.71
-
CSI 22.58rCSI 64.46%PRS 15.55
-
CSI 22.27rCSI 60.04%PRS 11.35
-
CSI 21.47rCSI 62.16%PRS 9.97
-
CSI 20.2rCSI 27%PRS 16.84
-
CSI 19.54rCSI 17.94%PRS 10.05
-
CSI 19.21rCSI 26.25%PRS 9.71
-
CSI 18.92rCSI 20.28%PRS 8.09
-
CSI 18.65rCSI 39.67%PRS 16.08
-
CSI 18.24rCSI 27.81%PRS 8.22
-
CSI 18.18rCSI 24.3%PRS 11.72
-
CSI 17.44rCSI 55.97%PRS 13.09
-
CSI 16.78rCSI 32.64%PRS 8.97
-
CSI 15.76rCSI 20.95%PRS 9.58
-
CSI 15.71rCSI 10.97%PRS 9.27
-
CSI 15.67rCSI 24.08%PRS 12.62
-
CSI 15.03rCSI 77.59%PRS 17.63
-
CSI 14.26rCSI 9.91%PRS 10.3
-
CSI 13.64rCSI 16.48%PRS 10.36
-
CSI 13.12rCSI 28.65%PRS 17.93
-
CSI 12.9rCSI 20.48%PRS 11.41
-
CSI 12.77rCSI 12.75%PRS 7.55
-
CSI 12.43rCSI 9.83%PRS 6.05
-
CSI 12.2rCSI 14.85%PRS 11.1
-
CSI 11.91rCSI 46.36%PRS 14.55
-
CSI 11.9rCSI 42.25%PRS 14.43
-
CSI 11.83rCSI 51.95%PRS 16.44
-
CSI 11.75rCSI 6.94%PRS 12.19
-
CSI 11.67rCSI 62.97%PRS 16.74
-
CSI 11.54rCSI 86.64%PRS 16.3
-
CSI 11.5rCSI 11.91%PRS 10.35
-
CSI 11.47rCSI 15.04%PRS 41.64
-
CSI 10.91rCSI 8.49%PRS 12.66
-
CSI 10.74rCSI 48.84%PRS 32.32
-
CSI 10.68rCSI 15.66%PRS 11.6
-
CSI 10.57rCSI 12.69%PRS 8.73
-
CSI 10.25rCSI 35.95%PRS 15.95
-
CSI 10.17rCSI 7.65%PRS 9.09
-
CSI 10.09rCSI 34.73%PRS 36.04
-
CSI 10.09rCSI 29.77%PRS 10.97
-
CSI 10.05rCSI 58.48%PRS 13.25
-
CSI 9.98rCSI 6.72%PRS 10.58
-
CSI 9.92rCSI 11.16%PRS 14.28
-
CSI 9.83rCSI 29.3%PRS 22.7
-
CSI 9.58rCSI 13.1%PRS 10
-
CSI 9.56rCSI 14%PRS 10.3
-
CSI 9.51rCSI 51.42%PRS 30.36
-
CSI 9.45rCSI 8.73%PRS 16.14
-
CSI 9.31rCSI 36%PRS 18.66
-
CSI 9.29rCSI 16.88%PRS 13.43
-
CSI 9.28rCSI 11.43%PRS 29.1
-
CSI 9.23rCSI 36.88%PRS 19.48
-
CSI 9.18rCSI 71.91%PRS 19.87
-
CSI 9.16rCSI 9.04%PRS 35.88
-
CSI 9.11rCSI 99.78%PRS 16.08
-
CSI 8.92rCSI 12.39%PRS 9.08
-
CSI 8.77rCSI 11.02%PRS 41.68
-
CSI 8.76rCSI 6.49%PRS 7.95
-
CSI 8.65rCSI 6.07%PRS 24.44
-
CSI 8.65rCSI 11.1%PRS 8.57
-
CSI -7.5rCSI -12.0%PRS 5.7%
-
CSI -5.4rCSI -9.4%PRS 6.5%
-
CSI -5.1rCSI -18.3%PRS 4.7%
-
CSI -5.1rCSI -6.9%PRS 13.5%
-
CSI -5.0rCSI -7.3%PRS 8.4%
-
CSI -4.2rCSI -3.9%PRS 13.6%
-
CSI -3.0rCSI -7.1%PRS 11.5%
-
CSI -3.0rCSI -5.2%PRS 11.7%
-
CSI -2.9rCSI -4.5%PRS 21.9%
-
CSI -2.3rCSI -5.1%PRS 5.4%
-
CSI -2.1rCSI -3.3%PRS 9.6%
-
CSI -1.8rCSI -4.6%PRS 14.8%
-
CSI -1.4rCSI -1.4%PRS 13.9%
-
CSI -1.3rCSI -31.5%PRS 4.6%
-
CSI -1.1rCSI -5.8%PRS 38.4%
-
CSI -0.9rCSI -1.9%PRS 18.7%
-
CSI -0.9rCSI -5.2%PRS 5.5%
-
CSI -0.8rCSI -2.2%PRS 12.8%
-
CSI -0.7rCSI -1.5%PRS 8.8%
-
CSI -0.7rCSI -0.9%PRS 4.8%
-
CSI -0.7rCSI -1.1%PRS 8.8%
-
CSI -0.7rCSI -2.5%PRS 5.3%
-
CSI -0.6rCSI -0.8%PRS 15.3%
-
CSI -0.6rCSI -15.4%PRS 3.8%
-
CSI -0.6rCSI -1.7%PRS 8.7%
-
CSI -0.5rCSI -3.1%PRS 54.5%
-
CSI -0.3rCSI -0.8%PRS 5.6%
-
CSI -0.1rCSI -0.3%PRS 5.0%
-
CSI -0.1rCSI -0.1%PRS 31.7%
-
CSI 0.0rCSI 0.2%PRS 7.0%
-
CSI 0.1rCSI 1.5%PRS 43.3%
-
CSI 0.1rCSI 2.5%PRS 29.6%
-
CSI 0.1rCSI 0.6%PRS 13.2%
-
CSI 0.2rCSI 4.7%PRS 70.5%
-
CSI 0.2rCSI 3.9%PRS 63.2%
-
CSI 0.2rCSI 4.3%PRS 31.6%
-
CSI 0.2rCSI 4.0%PRS 59.4%
-
CSI 0.2rCSI 1.0%PRS 35.4%
-
CSI 0.2rCSI 0.3%PRS 12.4%
-
CSI 0.3rCSI 0.4%PRS 12.6%
-
CSI 0.3rCSI 2.4%PRS 29.8%
-
CSI 0.3rCSI 1.5%PRS 16.0%
-
CSI 0.3rCSI 0.5%PRS 5.2%
-
CSI 0.4rCSI 1.1%PRS 7.1%
-
CSI 0.4rCSI 0.8%PRS 6.5%
-
CSI 0.4rCSI 6.8%PRS 48.8%
-
CSI 0.5rCSI 1.5%PRS 26.1%
-
CSI 0.5rCSI 0.7%PRS 9.2%
-
CSI 0.5rCSI 1.5%PRS 11.1%
-
CSI 0.5rCSI 1.1%PRS 27.3%
-
CSI 0.6rCSI 1.5%PRS 6.8%
-
CSI 0.6rCSI 1.5%PRS 9.3%
-
CSI 0.6rCSI 1.6%PRS 10.5%
-
CSI 0.6rCSI 5.1%PRS 37.6%
-
CSI 0.7rCSI 4.3%PRS 29.3%
-
CSI 0.7rCSI 2.1%PRS 6.0%
-
CSI 0.7rCSI 1.5%PRS 13.5%
-
CSI 0.7rCSI 0.8%PRS 5.1%
-
CSI 0.7rCSI 10.7%PRS 28.7%
-
CSI 0.7rCSI 4.9%PRS 17.3%
-
CSI 0.7rCSI 8.0%PRS 37.4%
-
CSI 0.8rCSI 2.2%PRS 16.2%
-
CSI 0.8rCSI 1.4%PRS 8.9%
-
CSI 0.8rCSI 3.3%PRS 23.5%
-
CSI 0.8rCSI 3.5%PRS 8.7%
-
CSI 0.8rCSI 1.2%PRS 13.0%
-
CSI 0.9rCSI 3.3%PRS 13.3%
-
CSI 0.9rCSI 3.8%PRS 17.1%
-
CSI 0.9rCSI 5.6%PRS 39.0%
-
CSI 1.0rCSI 2.2%PRS 19.8%
-
CSI 1.1rCSI 4.7%PRS 37.6%
-
CSI 1.1rCSI 5.4%PRS 11.6%
-
CSI 1.1rCSI 2.6%PRS 13.4%
-
CSI 1.1rCSI 1.2%PRS 10.2%
-
CSI 1.1rCSI 1.8%PRS 7.7%
-
CSI 1.2rCSI 2.3%PRS 24.4%
-
CSI 1.2rCSI 2.0%PRS 5.2%
-
CSI 1.2rCSI 4.3%PRS 15.2%
-
CSI 1.2rCSI 2.8%PRS 14.0%
-
CSI 1.3rCSI 2.9%PRS 7.4%
-
CSI 1.3rCSI 2.7%PRS 44.8%
-
CSI 1.3rCSI 34.3%PRS 43.7%
-
CSI 1.4rCSI 7.7%PRS 28.1%
-
CSI 1.4rCSI 31.8%PRS 56.5%
-
CSI 1.5rCSI 1.8%PRS 13.5%
-
CSI 1.5rCSI 3.8%PRS 25.6%
-
CSI 1.5rCSI 4.8%PRS 10.8%
-
CSI 1.5rCSI 32.2%PRS 48.7%
-
CSI 1.5rCSI 2.9%PRS 24.9%
-
CSI 1.5rCSI 3.4%PRS 9.7%
-
CSI 1.6rCSI 4.2%PRS 12.2%
-
CSI 1.6rCSI 1.3%PRS 9.4%
-
CSI 1.6rCSI 7.3%PRS 8.8%
-
CSI 1.7rCSI 6.3%PRS 9.2%
-
CSI 1.7rCSI 7.5%PRS 43.1%
-
CSI 1.7rCSI 2.1%PRS 9.4%
-
CSI 1.8rCSI 5.1%PRS 19.8%
-
CSI 1.8rCSI 2.7%PRS 13.6%
-
CSI 1.8rCSI 3.6%PRS 13.8%
-
CSI 1.8rCSI 17.0%PRS 38.1%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 481862021
Symbol: AT5F1_HUMAN
Name: ATP synthase proton-transporting mitochondrial F(0) complex subunit B1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1831354
Title: Molecular cloning of cDNA for the import precursor of human subunit B of H(+)-ATP synthase in mitochondria.
PubMed ID: 1831354
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 256
- Mass: 28909
- Checksum: 743B1C54BFFEBBBD
- Sequence:
MLSRVVLSAA ATAAPSLKNA AFLGPGVLQA TRTFHTGQPH LVPVPPLPEY GGKVRYGLIP EEFFQFLYPK TGVTGPYVLG TGLILYALSK EIYVISAETF TALSVLGVMV YGIKKYGPFV ADFADKLNEQ KLAQLEEAKQ ASIQHIQNAI DTEKSQQALV QKRHYLFDVQ RNNIAMALEV TYRERLYRVY KEVKNRLDYH ISVQNMMRRK EQEHMINWVE KHVVQSISTQ QEKETIAKCI ADLKLLAKKA QAQPVM