Hnrnpu | ENSMUSG00000039630 | NCBI 51810

Details for: Hnrnpu

Gene ID: 51810

Symbol: Hnrnpu

Ensembl ID: ENSMUSG00000039630

Description: heterogeneous nuclear ribonucleoprotein U

Associated with

Metabolism of rna
(R-MMU-8953854)
Mrna splicing
(R-MMU-72172)
Mrna splicing - major pathway
(R-MMU-72163)
Processing of capped intron-containing pre-mrna
(R-MMU-72203)
Actin binding
(GO:0003779)
Adaptive thermogenesis
(GO:1990845)
Alternative mrna splicing, via spliceosome
(GO:0000380)
Atp binding
(GO:0005524)
Cardiac muscle cell development
(GO:0055013)
Catalytic step 2 spliceosome
(GO:0071013)
Cell division
(GO:0051301)
Cell surface
(GO:0009986)
Cellular response to dexamethasone stimulus
(GO:0071549)
Cellular response to glucocorticoid stimulus
(GO:0071385)
Cellular response to leukemia inhibitory factor
(GO:1990830)
Centrosome
(GO:0005813)
Chromatin binding
(GO:0003682)
Chromatin dna binding
(GO:0031490)
Circadian regulation of gene expression
(GO:0032922)
Crd-mediated mrna stability complex
(GO:0070937)
Crd-mediated mrna stabilization
(GO:0070934)
Cytoplasmic ribonucleoprotein granule
(GO:0036464)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
Dendritic transport of messenger ribonucleoprotein complex
(GO:0098963)
Dna binding
(GO:0003677)
Dosage compensation by inactivation of x chromosome
(GO:0009048)
Double-stranded dna binding
(GO:0003690)
Double-stranded rna binding
(GO:0003725)
Erythrocyte differentiation
(GO:0030218)
Identical protein binding
(GO:0042802)
Inactive sex chromosome
(GO:0098577)
Kinetochore
(GO:0000776)
Lncrna binding
(GO:0106222)
Maintenance of protein location in nucleus
(GO:0051457)
Midbody
(GO:0030496)
Mitotic spindle
(GO:0072686)
Mrna 3'-utr binding
(GO:0003730)
Mrna metabolic process
(GO:0016071)
Mrna processing
(GO:0006397)
Mrna stabilization
(GO:0048255)
Negative regulation of kinase activity
(GO:0033673)
Negative regulation of nuclear-transcribed mrna catabolic process, deadenylation-dependent decay
(GO:1900152)
Negative regulation of stem cell differentiation
(GO:2000737)
Negative regulation of telomere maintenance via telomerase
(GO:0032211)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Negative regulation of transcription elongation by rna polymerase ii
(GO:0034244)
Nuclear chromosome
(GO:0000228)
Nuclear matrix
(GO:0016363)
Nuclear speck
(GO:0016607)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Pirna binding
(GO:0034584)
Poly(a) binding
(GO:0008143)
Poly(c) rna binding
(GO:0017130)
Poly(g) binding
(GO:0034046)
Positive regulation of attachment of mitotic spindle microtubules to kinetochore
(GO:1902425)
Positive regulation of brown fat cell differentiation
(GO:0090336)
Positive regulation of cytoplasmic translation
(GO:2000767)
Positive regulation of dna topoisomerase (atp-hydrolyzing) activity
(GO:2000373)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of stem cell proliferation
(GO:2000648)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Pre-mrna binding
(GO:0036002)
Promoter-specific chromatin binding
(GO:1990841)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein localization to spindle microtubule
(GO:1902889)
Random inactivation of x chromosome
(GO:0060816)
Regulation of alternative mrna splicing, via spliceosome
(GO:0000381)
Regulation of chromatin organization
(GO:1902275)
Regulation of mitotic cell cycle
(GO:0007346)
Regulation of mitotic spindle assembly
(GO:1901673)
Regulatory ncrna-mediated heterochromatin formation
(GO:0031048)
Ribonucleoprotein complex binding
(GO:0043021)
Rna binding
(GO:0003723)
Rna localization to chromatin
(GO:1990280)
Rna polymerase ii c-terminal domain binding
(GO:0099122)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii complex binding
(GO:0000993)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Rna splicing
(GO:0008380)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Single-stranded dna binding
(GO:0003697)
Single-stranded rna binding
(GO:0003727)
Snrna binding
(GO:0017069)
Spindle pole
(GO:0000922)
Telomerase holoenzyme complex
(GO:0005697)
Telomerase rna binding
(GO:0070034)
Tfiih-class transcription factor complex binding
(GO:0001097)
Transcription corepressor activity
(GO:0003714)

Other Information

Proteins

HNRPU_MOUSE

Genular Protein ID: 2351197995

Symbol: HNRPU_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8VEK3 G3XA10 Q9R205

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16022389

Title: Hypomorphic mutation in hnRNP U results in post-implantation lethality.

PubMed ID: 16022389

DOI: 10.1007/s11248-004-8147-8

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

DOI: 10.4049/jimmunol.179.9.5864

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 18332112

Title: Rhythmic SAF-A binding underlies circadian transcription of the Bmal1 gene.

PubMed ID: 18332112

DOI: 10.1128/mcb.02227-07

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19129230

Title: Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter.

PubMed ID: 19129230

DOI: 10.1093/nar/gkn1013

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20833368

Title: The matrix protein hnRNP U is required for chromosomal localization of Xist RNA.

PubMed ID: 20833368

DOI: 10.1016/j.devcel.2010.08.006

PubMed ID: 21235343

Title: SAF-A has a role in transcriptional regulation of Oct4 in ES cells through promoter binding.

PubMed ID: 21235343

DOI: 10.1089/cell.2010.0075

PubMed ID: 22162999

Title: SAF-A forms a complex with BRG1 and both components are required for RNA polymerase II mediated transcription.

PubMed ID: 22162999

DOI: 10.1371/journal.pone.0028049

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 24463520

Title: Citrullination regulates pluripotency and histone H1 binding to chromatin.

PubMed ID: 24463520

DOI: 10.1038/nature12942

PubMed ID: 26244333

Title: Xist exon 7 contributes to the stable localization of Xist RNA on the inactive X-chromosome.

PubMed ID: 26244333

DOI: 10.1371/journal.pgen.1005430

PubMed ID: 28784777

Title: Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis.

PubMed ID: 28784777

DOI: 10.1073/pnas.1703494114

Sequence Information:

Length: 800
Mass: 87918
Checksum: 2BA7C73043F847B2
Sequence:

MSSSPVNVKK LKVSELKEEL KKRRLSDKGL KADLMDRLQA ALDNEAGGRP AMEPGNGSLD 
LGGDAAGRSG AGLEQEAAAG AEDDEEEEGI AALDGDQMEL GEENGAAGAA DAGAMEEEEA 
ASEDENGDDQ GFQEGEDELG DEEEGAGDEN GHGEQQSQPP AAAAQQQPSQ QRGAGKEAAG 
KSSGPTSLFA VTVAPPGARQ GQQQAGGDGK TEQKGGDKKR GVKRPREDHG RGYFEYIEEN 
KYSRAKSPQP PVEEEDEHFD DTVVCLDTYN CDLHFKISRD RLSASSLTME SFAFLWAGGR 
ASYGVSKGKV CFEMKVTEKI PVRHLYTKDI DIHEVRIGWS LTTSGMLLGE EEFSYGYSLK 
GIKTCNCETE DYGEKFDEND VITCFANFET DEVELSYAKN GQDLGVAFKI SKEVLADRPL 
FPHVLCHNCA VEFNFGQKEK PYFPIPEDCT FIQNVPLEDR VRGPKGPEEK KDCEVVMMIG 
LPGAGKTTWV TKHAAENPGK YNILGTNTIM DKMMVAGFKK QMADTGKLNT LLQRAPQCLG 
KFIEIAARKK RNFILDQTNV SAAAQRRKMC LFAGFQRKAV VVCPKDEDYK QRTQKKAEVE 
GKDLPEHAVL KMKGNFTLPE VAECFDEITY VELQKEEAQK LLEQYKEESK KALPPEKKQN 
TGSKKSNKNK SGKNQFNRGG GHRGRGGFNM RGGNFRGGAP GNRGGYNRRG NMPQRGGGGG 
SGGIGYPYPR GPVFPGRGGY SNRGNYNRGG MPNRGNYNQN FRGRGNNRGY KNQSQGYNQW 
QQGQFWGQKP WSQHYHQGYY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hnrnpu

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Hypomorphic mutation in hnRNP U results in post-implantation lethality. PubMed ID: 16022389

Comprehensive identification of phosphorylation sites in postsynaptic density preparations. PubMed ID: 16452087

Quantitative time-resolved phosphoproteomic analysis of mast cell signaling. PubMed ID: 17947660

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

Rhythmic SAF-A binding underlies circadian transcription of the Bmal1 gene. PubMed ID: 18332112

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter. PubMed ID: 19129230

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

The matrix protein hnRNP U is required for chromosomal localization of Xist RNA. PubMed ID: 20833368

SAF-A has a role in transcriptional regulation of Oct4 in ES cells through promoter binding. PubMed ID: 21235343

SAF-A forms a complex with BRG1 and both components are required for RNA polymerase II mediated transcription. PubMed ID: 22162999

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315

Citrullination regulates pluripotency and histone H1 binding to chromatin. PubMed ID: 24463520

Xist exon 7 contributes to the stable localization of Xist RNA on the inactive X-chromosome. PubMed ID: 26244333

Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis. PubMed ID: 28784777