Rragd | ENSMUSG00000028278 | NCBI 52187

Details for: Rragd

Gene ID: 52187

Symbol: Rragd

Ensembl ID: ENSMUSG00000028278

Description: Ras-related GTP binding D

Associated with

Amino acids regulate mtorc1
(R-MMU-9639288)
Autophagy
(R-MMU-9612973)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Energy dependent regulation of mtor by lkb1-ampk
(R-MMU-380972)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Intracellular signaling by second messengers
(R-MMU-9006925)
Macroautophagy
(R-MMU-1632852)
Mtorc1-mediated signalling
(R-MMU-166208)
Mtor signalling
(R-MMU-165159)
Pip3 activates akt signaling
(R-MMU-1257604)
Pten regulation
(R-MMU-6807070)
Regulation of pten gene transcription
(R-MMU-8943724)
Rna polymerase ii transcription
(R-MMU-73857)
Signal transduction
(R-MMU-162582)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional regulation by tp53
(R-MMU-3700989)
Cellular response to l-leucine
(GO:0071233)
Cellular response to leucine starvation
(GO:1990253)
Cellular response to starvation
(GO:0009267)
Centrosome
(GO:0005813)
Cytoplasm
(GO:0005737)
Gdp binding
(GO:0019003)
Gtpase activity
(GO:0003924)
Gtpase binding
(GO:0051020)
Gtp binding
(GO:0005525)
Gtr1-gtr2 gtpase complex
(GO:1990131)
Intracellular membrane-bounded organelle
(GO:0043231)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Molecular adaptor activity
(GO:0060090)
Negative regulation of autophagy
(GO:0010507)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of torc1 signaling
(GO:1904263)
Protein heterodimerization activity
(GO:0046982)

Other Information

Proteins

Ras-related GTP-binding protein D
B1AWT2_MOUSE

Genular Protein ID: 3723958206

Symbol: RRAGD_MOUSE

Name: Ras-related GTP-binding protein D

UniProtKB Accession Codes:

Q7TT45 Q6GTT2 Q9CYC2

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 25259925

Title: Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.

PubMed ID: 25259925

DOI: 10.1016/j.cell.2014.08.038

PubMed ID: 30595499

Title: Lysosomal signaling licenses embryonic stem cell differentiation via inactivation of Tfe3.

PubMed ID: 30595499

DOI: 10.1016/j.stem.2018.11.021

PubMed ID: 34607910

Title: mTOR-Activating Mutations in RRAGD Are Causative for Kidney Tubulopathy and Cardiomyopathy.

PubMed ID: 34607910

DOI: 10.1681/asn.2021030333

Sequence Information:

Length: 449
Mass: 51232
Checksum: 6D9AC2A86DE5784A
Sequence:

MSQVLGKPQP QGEDGGEDQE EDELVGLAGY EDGPESSDAE LDSGPEEGES RRNSWMPRSW 
CSEATRHECW EPGLWRSSHL LGIGGGWRML RRQRQADFFL DFSDPFSTEV KPRILLMGLR 
RSGKSSIQKV VFHKMSPSET LFLESTNRIC REDVSNSSFV NFQIWDFPGQ IDFFDPTFDY 
EMIFRGTGAL IFVIDSQDDY MEALARLHLT VTRAYKVNTD INFEVFIHKV DGLSDDHKIE 
TQRDIHQRAN DDLADAGLEK IHLSFYLTSI YDHSIFEAFS KVVQKLIPQL PTLENLLNIF 
ISNSGIEKAF LFDVVSKIYI ATDSTPVDMQ TYELCCDMID VVIDISCIYG LKEDGAGAPY 
DKDSTAIIKL NNTTVLYLKE VTKFLALVCF VREESFERKG LIDYNFHCFR KAIHEVFEVR 
MKMVKSRKAQ SRLPKKTGAT PNGTPRVLL

Genular Protein ID: 1250370569

Symbol: B1AWT2_MOUSE

Name: N/A

UniProtKB Accession Codes:

B1AWT2

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

Length: 399
Mass: 45145
Checksum: 58010DD934BAB898
Sequence:

MSQVLGKPQP QGEDGGEDEE EDELVGLAGY EDGPESSDAE LDSGPEEGVL DFSDPFSTEV 
KPRILLMGLR RSGKSSIQKV VFHKMSPSET LFLESTNRIC REDVSNSSFV NFQIWDFPGQ 
IDFFDPTFDY EMIFRGTGAL IFVIDSQDDY MEALARLHLT VTRAYKVNTD INFEVFIHKV 
DGLSDDHKIE TQRDIHQRAN DDLADAGLEK IHLSFYLTSI YDHSIFEAFS KVVQKLIPQL 
PTLENLLNIF ISNSGIEKAF LFDVVSKIYI ATDSTPVDMQ TYELCCDMID VVIDISCIYG 
LKEDGAGAPY DKDSTAIIKL NNTTVLYLKE VTKFLALVCF VREESFERKG LIDYNFHCFR 
KAIHEVFEVR MKMVKSRKAQ SRLPKKTGAT PNGTPRVLL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rragd

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling. PubMed ID: 25259925

Lysosomal signaling licenses embryonic stem cell differentiation via inactivation of Tfe3. PubMed ID: 30595499

mTOR-Activating Mutations in RRAGD Are Causative for Kidney Tubulopathy and Cardiomyopathy. PubMed ID: 34607910

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Modernizing reference genome assemblies. PubMed ID: 21750661