Details for: Suz12

Gene ID: 52615

Symbol: Suz12

Ensembl ID: ENSMUSG00000017548

Description: SUZ12 polycomb repressive complex 2 subunit

Associated with

Other Information

Genular Protein ID: 589931871

Symbol: SUZ12_MOUSE

Name: Polycomb protein Suz12

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12693553

Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PubMed ID: 12693553

DOI: 10.1093/dnares/10.1.35

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15385962

Title: Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity.

PubMed ID: 15385962

DOI: 10.1038/sj.emboj.7600402

PubMed ID: 15516932

Title: Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes.

PubMed ID: 15516932

DOI: 10.1038/ng1467

PubMed ID: 15684044

Title: Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation.

PubMed ID: 15684044

DOI: 10.1073/pnas.0409875102

PubMed ID: 16712789

Title: Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively in vitro.

PubMed ID: 16712789

DOI: 10.1016/j.bbrc.2006.05.014

PubMed ID: 16415857

Title: The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation.

PubMed ID: 16415857

DOI: 10.1038/ncb1351

PubMed ID: 17339329

Title: The polycomb group protein Suz12 is required for embryonic stem cell differentiation.

PubMed ID: 17339329

DOI: 10.1128/mcb.01432-06

PubMed ID: 19026780

Title: EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.

PubMed ID: 19026780

DOI: 10.1016/j.molcel.2008.10.016

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20144788

Title: Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.

PubMed ID: 20144788

DOI: 10.1016/j.stem.2009.12.014

PubMed ID: 22226355

Title: Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells.

PubMed ID: 22226355

DOI: 10.1016/j.stem.2011.12.006

PubMed ID: 23970558

Title: Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes.

PubMed ID: 23970558

DOI: 10.1126/science.1240636

Sequence Information:

  • Length: 741
  • Mass: 83026
  • Checksum: 4A6B6E52D24FAEF2
  • Sequence:
  • MAPQKHGGGG GGGSGPSAGS GGGGFGGSAA AVAAAASGGK SGGGGCGGGG SYSASSSSAA 
    AAAAAAGAAV LPVKKPKMEH VQADHELFLQ AFEKPTQIYR FLRTRNLIAP IFLHRTLTYM 
    SHRNSRTSIK RKTFKVDDML SKVEKMKGEQ ESHSLSAHLQ LTFTGFFHKN DKPSQNSENE 
    QNSVTLEVLL VKVCHKKRKD VSCPIRQVPT GKKQVPLNPD LNQTKPGNFP SLAVSSNEFE 
    PSNSHMVKSY SLLFRVTRPG RREFNGMING ETNENIDVSE ELPARRKRNR EDGEKTFVAQ 
    MTVFDKNRRL QLLDGEYEVA MQEMEECPIS KKRATWETIL DGKRLPPFET FSQGPTLQFT 
    LRWTGETNDK STAPVAKPLA TRNSESLHQE NKPGSVKPAQ TIAVKETLTT ELQTRKEKDN 
    SNESRQKLRI FYQFLYNNNT RQQTEARDDL HCPWCTLNCR KLYSLLKHLK LCHSRFIFNY 
    VYHPKGARID VSINECYDGS YAGNPQDIHR QPGFAFSRNG PVKRTPITHI LVCRPKRTKA 
    SMSEFLESED GEVEQQRTYS SGHNRLYFHS DTCLPLRPQE MEVDSEDEKD PEWLREKTIT 
    QIEEFSDVNE GEKEVMKLWN LHVMKHGFIA DNQMNHACML FVENYGQKII KKNLCRNFML 
    HLVSMHDFNL ISIMSIDKAV TKLREMQQKL EKGESATPSN EEIAEEQNGT ANGFSETNSK 
    EKALETDGVS GVPKQSKKQK L

Genular Protein ID: 3528491816

Symbol: E9PW15_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21750661

Title: Modernizing reference genome assemblies.

PubMed ID: 21750661

Sequence Information:

  • Length: 718
  • Mass: 80293
  • Checksum: C19880A827EA44F1
  • Sequence:
  • MAPQKHGGGG GGGSGPSAGS GGGGFGGSAA AVAAAASGGK SGGGGCGGGG SYSASSSSAA 
    AAAAAAGAAV LPVKKPKMEH VQADHELFLQ AFEKPTQIYR FLRTRNLIAP IFLHRTLTYM 
    SHRNSRTSIK SLSAHLQLTF TGFFHKNDKP SQNSENEQNS VTLEVLLVKV CHKKRKDVSC 
    PIRQVPTGKK QVPLNPDLNQ TKPGNFPSLA VSSNEFEPSN SHMVKSYSLL FRVTRPGRRE 
    FNGMINGETN ENIDVSEELP ARRKRNREDG EKTFVAQMTV FDKNRRLQLL DGEYEVAMQE 
    MEECPISKKR ATWETILDGK RLPPFETFSQ GPTLQFTLRW TGETNDKSTA PVAKPLATRN 
    SESLHQENKP GSVKPAQTIA VKETLTTELQ TRKEKDNSNE SRQKLRIFYQ FLYNNNTRQQ 
    TEARDDLHCP WCTLNCRKLY SLLKHLKLCH SRFIFNYVYH PKGARIDVSI NECYDGSYAG 
    NPQDIHRQPG FAFSRNGPVK RTPITHILVC RPKRTKASMS EFLESEDGEV EQQRTYSSGH 
    NRLYFHSDTC LPLRPQEMEV DSEDEKDPEW LREKTITQIE EFSDVNEGEK EVMKLWNLHV 
    MKHGFIADNQ MNHACMLFVE NYGQKIIKKN LCRNFMLHLV SMHDFNLISI MSIDKAVTKL 
    REMQQKLEKG ESATPSNEEI AEEQNGTANG FSETNSKEKA LETDGVSGVP KQSKKQKL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.