Details for: Nit2

Gene ID: 52633

Symbol: Nit2

Ensembl ID: ENSMUSG00000022751

Description: nitrilase family, member 2

Associated with

Other Information

Genular Protein ID: 2874035648

Symbol: NIT2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9JHW2 Q9CTG9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 12 ChiTaRS 1 DNASU 1 EC 3 EMBL 4 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 8 Gene3D 1 GeneTree 1 HOGENOM 1 InParanoid 1 InterPro 3 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 6 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 10959838

Title: Crystal structure of the worm NitFhit Rosetta stone protein reveals a Nit tetramer binding two Fhit dimers.

PubMed ID: 10959838

DOI: 10.1016/s0960-9822(00)00621-7

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19596042

Title: Molecular identification of omega-amidase, the enzyme that is functionally coupled with glutamine transaminases, as the putative tumor suppressor Nit2.

PubMed ID: 19596042

DOI: 10.1016/j.biochi.2009.07.002

PubMed ID: 19595734

Title: Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination.

PubMed ID: 19595734

DOI: 10.1016/j.biochi.2009.07.003

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 28373563

Title: Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione.

PubMed ID: 28373563

DOI: 10.1073/pnas.1613736114

PubMed ID: 19053248

Title: Functional proteomic and structural insights into molecular recognition in the nitrilase family enzymes.

PubMed ID: 19053248

DOI: 10.1021/bi801786y

Sequence Information:

  • Length: 276
  • Mass: 30502
  • Checksum: 740FDC44978326D6
  • Sequence:
    • MSTFRLALIQ LQVSSIKSDN LTRACSLVRE AAKQGANIVS LPECFNSPYG TTYFPDYAEK 
IPGESTQKLS EVAKESSIYL IGGSIPEEDA GKLYNTCSVF GPDGSLLVKH RKIHLFDIDV 
PGKITFQESK TLSPGDSFST FDTPYCKVGL GICYDMRFAE LAQIYAQRGC QLLVYPGAFN 
LTTGPAHWEL LQRARAVDNQ VYVATASPAR DDKASYVAWG HSTVVDPWGQ VLTKAGTEET 
ILYSDIDLKK LAEIRQQIPI LKQKRADLYT VESKKP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.