ATP6V0C | ENSG00000185883 | NCBI 527

Details for: ATP6V0C

Gene ID: 527

Symbol: ATP6V0C

Ensembl ID: ENSG00000185883

Description: ATPase H+ transporting V0 subunit c

Associated with

Amino acids regulate mtorc1
(R-HSA-9639288)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to starvation
(R-HSA-9711097)
Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Insulin receptor recycling
(R-HSA-77387)
Ion channel transport
(R-HSA-983712)
Iron uptake and transport
(R-HSA-917937)
Neutrophil degranulation
(R-HSA-6798695)
Ros and rns production in phagocytes
(R-HSA-1222556)
Signaling by insulin receptor
(R-HSA-74752)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signal transduction
(R-HSA-162582)
Transferrin endocytosis and recycling
(R-HSA-917977)
Transport of small molecules
(R-HSA-382551)
Azurophil granule membrane
(GO:0035577)
Clathrin-coated vesicle membrane
(GO:0030665)
Endosomal lumen acidification
(GO:0048388)
Endosome membrane
(GO:0010008)
Extracellular exosome
(GO:0070062)
Ficolin-1-rich granule membrane
(GO:0101003)
Focal adhesion
(GO:0005925)
Golgi lumen acidification
(GO:0061795)
Golgi membrane
(GO:0000139)
Intracellular ph reduction
(GO:0051452)
Lysosomal lumen acidification
(GO:0007042)
Lysosomal membrane
(GO:0005765)
Membrane
(GO:0016020)
Phagocytic vesicle membrane
(GO:0030670)
Plasma membrane
(GO:0005886)
Positive regulation of wnt signaling pathway
(GO:0030177)
Protein binding
(GO:0005515)
Proton-transporting atpase activity, rotational mechanism
(GO:0046961)
Proton-transporting atp synthase activity, rotational mechanism
(GO:0046933)
Proton-transporting v-type atpase complex
(GO:0033176)
Proton motive force-driven atp synthesis
(GO:0015986)
Proton transmembrane transport
(GO:1902600)
Regulation of macroautophagy
(GO:0016241)
Synaptic vesicle membrane
(GO:0030672)
Tertiary granule membrane
(GO:0070821)
Transmembrane transporter complex
(GO:1902495)
Ubiquitin protein ligase binding
(GO:0031625)
Vacuolar acidification
(GO:0007035)
Vacuolar proton-transporting v-type atpase, v0 domain
(GO:0000220)

Other Information

Proteins

VATL_HUMAN

Genular Protein ID: 3020301276

Symbol: VATL_HUMAN

Name: N/A

UniProtKB Accession Codes:

P27449 Q6FH26

Database IDs:

Citations:

PubMed ID: 1709739

Title: CpG island in the region of an autosomal dominant polycystic kidney disease locus defines the 5' end of a gene encoding a putative proton channel.

PubMed ID: 1709739

DOI: 10.1073/pnas.88.10.4289

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1532310

Title: Vacuolar type H(+)-ATPase genes: presence of four genes including pseudogenes for the 16-kDa proteolipid subunit in the human genome.

PubMed ID: 1532310

DOI: 10.1016/0006-291x(92)90562-y

PubMed ID: 7636472

Title: Mapping of the intermolecular association of human T cell leukaemia/lymphotropic virus type I p12I and the vacuolar H+-ATPase 16 kDa subunit protein.

PubMed ID: 7636472

DOI: 10.1099/0022-1317-76-8-1909

PubMed ID: 11543633

Title: Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1.

PubMed ID: 11543633

DOI: 10.1006/geno.2001.6614

PubMed ID: 18298843

Title: A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation.

PubMed ID: 18298843

DOI: 10.1186/1750-1326-3-4

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 33065002

Title: Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.

PubMed ID: 33065002

DOI: 10.1016/j.molcel.2020.09.029

Sequence Information:

Length: 155
Mass: 15736
Checksum: 91141854A0492A5B
Sequence:

MSESKSGPEY ASFFAVMGAS AAMVFSALGA AYGTAKSGTG IAAMSVMRPE QIMKSIIPVV 
MAGIIAIYGL VVAVLIANSL NDDISLYKSF LQLGAGLSVG LSGLAAGFAI GIVGDAGVRG 
TAQQPRLFVG MILILIFAEV LGLYGLIVAL ILSTK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ATP6V0C

Associated with

Other Information

CpG island in the region of an autosomal dominant polycystic kidney disease locus defines the 5' end of a gene encoding a putative proton channel. PubMed ID: 1709739

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Vacuolar type H(+)-ATPase genes: presence of four genes including pseudogenes for the 16-kDa proteolipid subunit in the human genome. PubMed ID: 1532310

Mapping of the intermolecular association of human T cell leukaemia/lymphotropic virus type I p12I and the vacuolar H+-ATPase 16 kDa subunit protein. PubMed ID: 7636472

Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1. PubMed ID: 11543633

A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation. PubMed ID: 18298843

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly. PubMed ID: 33065002