Details for: ATP6V1C1
Gene ID: 528
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: ATP6V1C1
Ensembl ID: ENSG00000155097
Description: ATPase H+ transporting V1 subunit C1
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 16.85rCSI 31.81%PRS 60.8
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CSI 15.6rCSI 14.39%PRS 51.35
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CSI 11.75rCSI 28.56%PRS 32.59
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CSI 10.78rCSI 16.66%PRS 48.2
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CSI 7.84rCSI 28.2%PRS 32.44
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CSI 7.6rCSI 11.67%PRS 58.19
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CSI 5.48rCSI 9.68%PRS 32.77
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CSI 5.27rCSI 3.91%PRS 43.4
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CSI 5.23rCSI 13.98%PRS 42.41
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CSI 4.76rCSI 14.86%PRS 35.07
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CSI 4.64rCSI 6.85%PRS 67.75
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CSI 4.48rCSI 3.47%PRS 51.06
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CSI 4.4rCSI 4.49%PRS 64
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CSI 4.28rCSI 25.21%PRS 35.11
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CSI 4.17rCSI 9.53%PRS 49.77
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CSI 3.88rCSI 18.6%PRS 49.26
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CSI 3.84rCSI 21.71%PRS 36.26
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CSI 3.4rCSI 4.23%PRS 32.01
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CSI 3.31rCSI 2.68%PRS 51.27
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CSI 3.28rCSI 13.35%PRS 46.89
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CSI 3.17rCSI 5.43%PRS 59.9
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CSI 3.02rCSI 8.6%PRS 49.29
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CSI 3.01rCSI 4.48%PRS 52.58
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CSI 2.98rCSI 2.47%PRS 49.14
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CSI 2.88rCSI 3.93%PRS 55.64
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CSI 2.7rCSI 3.25%PRS 48.3
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CSI 2.66rCSI 4.55%PRS 76.28
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CSI 2.66rCSI 5.06%PRS 67.01
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CSI 2.62rCSI 2.3%PRS 55.74
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CSI 2.61rCSI 3.01%PRS 40.37
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CSI 2.6rCSI 5.91%PRS 55.63
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CSI 2.58rCSI 3.29%PRS 56.12
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CSI 2.52rCSI 9.52%PRS 34.53
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CSI 2.51rCSI 2.08%PRS 51.78
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CSI 2.49rCSI 4.07%PRS 40.4
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CSI 2.47rCSI 2.34%PRS 50.89
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CSI 2.45rCSI 1.99%PRS 50.88
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CSI 2.44rCSI 1.93%PRS 37.71
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CSI 2.41rCSI 3.97%PRS 55.88
-
CSI 2.36rCSI 2.47%PRS 47.28
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CSI 2.35rCSI 3.03%PRS 34.73
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CSI 2.35rCSI 3.94%PRS 33.68
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CSI 2.35rCSI 4.13%PRS 47.98
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CSI 2.34rCSI 5.59%PRS 60.07
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CSI 2.31rCSI 4%PRS 40.77
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CSI 2.31rCSI 55.23%PRS 33.15
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CSI 2.27rCSI 4.61%PRS 31.82
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CSI 2.23rCSI 2.2%PRS 52.96
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CSI 2.2rCSI 4.56%PRS 47.89
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CSI 2.18rCSI 52.7%PRS 34.05
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CSI 2.16rCSI 2.58%PRS 33.56
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CSI 2.16rCSI 1.98%PRS 58.6
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CSI 2.16rCSI 2.71%PRS 63.78
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CSI 2.16rCSI 1.51%PRS 52.63
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CSI 2.13rCSI 8.61%PRS 48.71
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CSI 2.12rCSI 5.39%PRS 40.3
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CSI 2.12rCSI 1.97%PRS 50.04
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CSI 2.1rCSI 4.71%PRS 34.49
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CSI 2.04rCSI 2.72%PRS 58.94
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CSI 2.03rCSI 4.09%PRS 39.88
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CSI 2.01rCSI 3.21%PRS 43.89
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CSI 2.01rCSI 2.75%PRS 59.73
-
CSI 2.01rCSI 3.99%PRS 48.9
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CSI 1.98rCSI 3.55%PRS 48.91
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CSI 1.98rCSI 1.97%PRS 44.31
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CSI 1.94rCSI 3.63%PRS 39.54
-
CSI 1.92rCSI 4.38%PRS 43.2
-
CSI 1.91rCSI 2.33%PRS 58.18
-
CSI 1.91rCSI 1.68%PRS 39.09
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CSI 1.86rCSI 2.25%PRS 58.49
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CSI 1.86rCSI 4.3%PRS 40.93
-
CSI 1.85rCSI 2.94%PRS 61.29
-
CSI 1.81rCSI 2.48%PRS 45.54
-
CSI 1.8rCSI 1.74%PRS 40.95
-
CSI 1.79rCSI 1.73%PRS 50.68
-
CSI 1.79rCSI 6.69%PRS 42.87
-
CSI 1.77rCSI 1.86%PRS 53.65
-
CSI 1.76rCSI 2.26%PRS 48.26
-
CSI 1.71rCSI 2.72%PRS 42.99
-
CSI 1.69rCSI 2.09%PRS 46.17
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CSI 1.69rCSI 2.26%PRS 51.59
-
CSI 1.68rCSI 3.71%PRS 54.45
-
CSI 1.67rCSI 2.37%PRS 46.9
-
CSI 1.66rCSI 7.38%PRS 49.36
-
CSI 1.65rCSI 3.39%PRS 71.21
-
CSI 1.64rCSI 2.4%PRS 53.74
-
CSI 1.63rCSI 1.75%PRS 48.62
-
CSI 1.62rCSI 4.23%PRS 49.39
-
CSI 1.59rCSI 2.79%PRS 42.45
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CSI 1.59rCSI 2.54%PRS 54.34
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CSI 1.54rCSI 2.47%PRS 35.79
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CSI 1.53rCSI 2.26%PRS 55.71
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CSI 1.51rCSI 1.88%PRS 52.77
-
CSI 1.51rCSI 3.93%PRS 54.8
-
CSI 1.5rCSI 2.7%PRS 43.63
-
CSI 1.47rCSI 4.25%PRS 67.11
-
CSI 1.45rCSI 1.91%PRS 64
-
CSI 1.45rCSI 4.21%PRS 52.54
-
CSI 1.43rCSI 3.49%PRS 45.25
-
CSI 1.41rCSI 2.75%PRS 52.61
-
CSI 0.2rCSI 4.7%PRS 42.0%
-
CSI 0.3rCSI 4.2%PRS 42.0%
-
CSI 0.5rCSI 2.5%PRS 62.1%
-
CSI 0.6rCSI 4.2%PRS 37.8%
-
CSI 0.6rCSI 5.1%PRS 37.5%
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CSI 0.6rCSI 1.5%PRS 38.8%
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CSI 0.7rCSI 2.0%PRS 41.1%
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CSI 0.7rCSI 2.8%PRS 65.5%
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CSI 0.7rCSI 4.2%PRS 60.9%
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CSI 0.8rCSI 1.6%PRS 39.8%
-
CSI 0.8rCSI 0.7%PRS 54.7%
-
CSI 0.8rCSI 3.5%PRS 42.9%
-
CSI 0.8rCSI 2.6%PRS 38.5%
-
CSI 0.9rCSI 4.0%PRS 71.9%
-
CSI 0.9rCSI 3.0%PRS 47.0%
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CSI 0.9rCSI 2.1%PRS 47.9%
-
CSI 1.0rCSI 2.1%PRS 37.9%
-
CSI 1.1rCSI 1.7%PRS 40.6%
-
CSI 1.1rCSI 1.5%PRS 40.9%
-
CSI 1.1rCSI 1.7%PRS 46.9%
-
CSI 1.1rCSI 0.8%PRS 49.6%
-
CSI 1.1rCSI 2.9%PRS 49.0%
-
CSI 1.2rCSI 2.1%PRS 66.7%
-
CSI 1.2rCSI 1.8%PRS 53.1%
-
CSI 1.2rCSI 1.7%PRS 66.8%
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CSI 1.2rCSI 3.4%PRS 46.5%
-
CSI 1.3rCSI 2.8%PRS 57.4%
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CSI 1.3rCSI 4.0%PRS 37.4%
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CSI 1.3rCSI 3.1%PRS 59.7%
-
CSI 1.3rCSI 1.7%PRS 55.7%
-
CSI 1.3rCSI 1.8%PRS 52.8%
-
CSI 1.3rCSI 3.5%PRS 46.0%
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CSI 1.4rCSI 2.1%PRS 59.8%
-
CSI 1.4rCSI 2.8%PRS 52.6%
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CSI 1.4rCSI 3.5%PRS 45.3%
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CSI 1.5rCSI 4.2%PRS 52.5%
-
CSI 1.5rCSI 1.9%PRS 64.0%
-
CSI 1.5rCSI 4.3%PRS 67.1%
-
CSI 1.5rCSI 2.7%PRS 43.6%
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CSI 1.5rCSI 3.9%PRS 54.8%
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CSI 1.5rCSI 1.9%PRS 52.8%
-
CSI 1.5rCSI 2.3%PRS 55.7%
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CSI 1.5rCSI 2.5%PRS 35.8%
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CSI 1.6rCSI 2.5%PRS 54.3%
-
CSI 1.6rCSI 2.8%PRS 42.5%
-
CSI 1.6rCSI 4.2%PRS 49.4%
-
CSI 1.6rCSI 1.8%PRS 48.6%
-
CSI 1.6rCSI 2.4%PRS 53.7%
-
CSI 1.7rCSI 3.4%PRS 71.2%
-
CSI 1.7rCSI 7.4%PRS 49.4%
-
CSI 1.7rCSI 2.4%PRS 46.9%
-
CSI 1.7rCSI 3.7%PRS 54.5%
-
CSI 1.7rCSI 2.3%PRS 51.6%
-
CSI 1.7rCSI 2.1%PRS 46.2%
-
CSI 1.7rCSI 2.7%PRS 43.0%
-
CSI 1.8rCSI 2.3%PRS 48.3%
-
CSI 1.8rCSI 1.9%PRS 53.7%
-
CSI 1.8rCSI 6.7%PRS 42.9%
-
CSI 1.8rCSI 1.7%PRS 50.7%
-
CSI 1.8rCSI 1.7%PRS 41.0%
-
CSI 1.8rCSI 2.5%PRS 45.5%
-
CSI 1.9rCSI 2.9%PRS 61.3%
-
CSI 1.9rCSI 4.3%PRS 40.9%
-
CSI 1.9rCSI 2.3%PRS 58.5%
-
CSI 1.9rCSI 1.7%PRS 39.1%
-
CSI 1.9rCSI 2.3%PRS 58.2%
-
CSI 1.9rCSI 4.4%PRS 43.2%
-
CSI 1.9rCSI 3.6%PRS 39.5%
-
CSI 2.0rCSI 2.0%PRS 44.3%
-
CSI 2.0rCSI 3.6%PRS 48.9%
-
CSI 2.0rCSI 4.0%PRS 48.9%
-
CSI 2.0rCSI 2.8%PRS 59.7%
-
CSI 2.0rCSI 3.2%PRS 43.9%
-
CSI 2.0rCSI 4.1%PRS 39.9%
-
CSI 2.0rCSI 2.7%PRS 58.9%
-
CSI 2.1rCSI 4.7%PRS 34.5%
-
CSI 2.1rCSI 2.0%PRS 50.0%
-
CSI 2.1rCSI 5.4%PRS 40.3%
-
CSI 2.1rCSI 8.6%PRS 48.7%
-
CSI 2.2rCSI 1.5%PRS 52.6%
-
CSI 2.2rCSI 2.7%PRS 63.8%
-
CSI 2.2rCSI 2.0%PRS 58.6%
-
CSI 2.2rCSI 2.6%PRS 33.6%
-
CSI 2.2rCSI 52.7%PRS 34.1%
-
CSI 2.2rCSI 4.6%PRS 47.9%
-
CSI 2.2rCSI 2.2%PRS 53.0%
-
CSI 2.3rCSI 4.6%PRS 31.8%
-
CSI 2.3rCSI 55.2%PRS 33.2%
-
CSI 2.3rCSI 4.0%PRS 40.8%
-
CSI 2.3rCSI 5.6%PRS 60.1%
-
CSI 2.4rCSI 4.1%PRS 48.0%
-
CSI 2.4rCSI 3.9%PRS 33.7%
-
CSI 2.4rCSI 3.0%PRS 34.7%
-
CSI 2.4rCSI 2.5%PRS 47.3%
-
CSI 2.4rCSI 4.0%PRS 55.9%
-
CSI 2.4rCSI 1.9%PRS 37.7%
-
CSI 2.5rCSI 2.0%PRS 50.9%
-
CSI 2.5rCSI 2.3%PRS 50.9%
-
CSI 2.5rCSI 4.1%PRS 40.4%
-
CSI 2.5rCSI 2.1%PRS 51.8%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 2066094745
Symbol: VATC1_HUMAN
Name: V-type proton ATPase subunit C 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8250920
Title: Cloning and tissue distribution of subunits C, D, and E of the human vacuolar H(+)-ATPase.
PubMed ID: 8250920
PubMed ID: 11707601
Title: BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia.
PubMed ID: 11707601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2147024
Title: Molecular cloning of cDNA encoding the C subunit of H(+)-ATPase from bovine chromaffin granules.
PubMed ID: 2147024
PubMed ID: 12384298
Title: Molecular cloning and characterization of novel tissue-specific isoforms of the human vacuolar H(+)-ATPase C, G and d subunits, and their evaluation in autosomal recessive distal renal tubular acidosis.
PubMed ID: 12384298
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 33065002
Title: Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
PubMed ID: 33065002
Sequence Information:
- Length: 382
- Mass: 43942
- Checksum: 5626E2AB2BD66BA7
- Sequence:
MTEFWLISAP GEKTCQQTWE KLHAATSKNN NLAVTSKFNI PDLKVGTLDV LVGLSDELAK LDAFVEGVVK KVAQYMADVL EDSKDKVQEN LLANGVDLVT YITRFQWDMA KYPIKQSLKN ISEIIAKGVT QIDNDLKSRA SAYNNLKGNL QNLERKNAGS LLTRSLAEIV KKDDFVLDSE YLVTLLVVVP KLNHNDWIKQ YETLAEMVVP RSSNVLSEDQ DSYLCNVTLF RKAVDDFRHK ARENKFIVRD FQYNEEEMKA DKEEMNRLST DKKKQFGPLV RWLKVNFSEA FIAWIHVKAL RVFVESVLRY GLPVNFQAML LQPNKKTLKK LREVLHELYK HLDSSAAAII DAPMDIPGLN LSQQEYYPYV YYKIDCNLLE FK