Sco1 | ENSMUSG00000069844 | NCBI 52892

Details for: Sco1

Gene ID: 52892

Symbol: Sco1

Ensembl ID: ENSMUSG00000069844

Description: SCO1 cytochrome c oxidase assembly protein

Associated with

Aerobic respiration and respiratory electron transport
(R-MMU-1428517)
Complex iv assembly
(R-MMU-9864848)
Metabolism
(R-MMU-1430728)
Respiratory electron transport
(R-MMU-611105)
Copper ion homeostasis
(GO:0055070)
Cyclooxygenase pathway
(GO:0019371)
Gene expression
(GO:0010467)
Homeostasis of number of cells
(GO:0048872)
Immune response
(GO:0006955)
Intracellular copper ion homeostasis
(GO:0006878)
Intracellular iron ion homeostasis
(GO:0006879)
Intracellular zinc ion homeostasis
(GO:0006882)
Leukocyte differentiation
(GO:0002521)
Liver development
(GO:0001889)
Metal ion binding
(GO:0046872)
Mitochondrial cytochrome c oxidase assembly
(GO:0033617)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrion
(GO:0005739)
Mitochondrion organization
(GO:0007005)
Molecular_function
(GO:0003674)
Multicellular organism growth
(GO:0035264)
Myofibril
(GO:0030016)
Negative regulation of cellular response to insulin stimulus
(GO:1900077)
Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051898)
Negative regulation of proteasomal protein catabolic process
(GO:1901799)
Post-transcriptional regulation of gene expression
(GO:0010608)
Proteasomal protein catabolic process
(GO:0010498)
Protein localization to plasma membrane
(GO:0072659)
Protein secretion
(GO:0009306)
Regulation of cytochrome-c oxidase activity
(GO:1904959)
Spleen development
(GO:0048536)
Thymus development
(GO:0048538)

Other Information

Proteins

Protein SCO1 homolog, mitochondrial

Genular Protein ID: 240858996

Symbol: SCO1_MOUSE

Name: Protein SCO1 homolog, mitochondrial

UniProtKB Accession Codes:

Q5SUC9 Q3UTD6

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25683716

Title: The mitochondrial metallochaperone SCO1 is required to sustain expression of the high-affinity copper transporter CTR1 and preserve copper homeostasis.

PubMed ID: 25683716

DOI: 10.1016/j.celrep.2015.01.019

PubMed ID: 28973536

Title: The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart.

PubMed ID: 28973536

DOI: 10.1093/hmg/ddx344

Sequence Information:

Length: 284
Mass: 31617
Checksum: 9CEC7E19F9977FF5
Sequence:

MAALVRAAVV RSQCRQLWRL FPRGHGLRDV AERPRPEEAC SCLRSRAFSA GPPPPGAGPE 
PKGGQAGSHR PKPGPVSWKS LALTFAIGGS LLAGMKYFKK EKIEKLEKQR HRSIGKPLLG 
GPFSLTTHNG EPKTDKDYLG QWVLIYFGFT HCPDICPEEL EKMIEVVEEI DSIPSLPNLT 
PLFITIDPER DTKEAIATYV KEFSPKLVGL TGTKEEIDGV ARAYRVYYSP GPKDEDEDYI 
VDHTIIMYLI GPDGEFLDYF GQNKKKAEIA GSIAAHMRSH MKKR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sco1

Associated with

Other Information

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

The mitochondrial metallochaperone SCO1 is required to sustain expression of the high-affinity copper transporter CTR1 and preserve copper homeostasis. PubMed ID: 25683716