ATP6V1E1 | ENSG00000131100 | NCBI 529

Details for: ATP6V1E1

Gene ID: 529

Symbol: ATP6V1E1

Ensembl ID: ENSG00000131100

Description: ATPase H+ transporting V1 subunit E1

Associated with

Amino acids regulate mtorc1
(R-HSA-9639288)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to starvation
(R-HSA-9711097)
Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Insulin receptor recycling
(R-HSA-77387)
Ion channel transport
(R-HSA-983712)
Iron uptake and transport
(R-HSA-917937)
Ros and rns production in phagocytes
(R-HSA-1222556)
Signaling by insulin receptor
(R-HSA-74752)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signal transduction
(R-HSA-162582)
Transferrin endocytosis and recycling
(R-HSA-917977)
Transport of small molecules
(R-HSA-382551)
Apical plasma membrane
(GO:0016324)
Atpase binding
(GO:0051117)
Clathrin-coated vesicle membrane
(GO:0030665)
Cytosol
(GO:0005829)
Endosome
(GO:0005768)
Extracellular exosome
(GO:0070062)
Lysosomal membrane
(GO:0005765)
Microvillus
(GO:0005902)
Protein binding
(GO:0005515)
Proton-transporting atpase activity, rotational mechanism
(GO:0046961)
Proton-transporting two-sector atpase complex
(GO:0016469)
Proton transmembrane transport
(GO:1902600)
Regulation of macroautophagy
(GO:0016241)
Synaptic vesicle lumen acidification
(GO:0097401)
Synaptic vesicle membrane
(GO:0030672)
Vacuolar proton-transporting v-type atpase, v1 domain
(GO:0000221)

Other Information

Proteins

V-type proton ATPase subunit E 1

Genular Protein ID: 3353807900

Symbol: VATE1_HUMAN

Name: V-type proton ATPase subunit E 1

UniProtKB Accession Codes:

P36543 A8MUE4 A8MUN4

Database IDs:

Citations:

PubMed ID: 1533641

Title: Immunologic evidence that vacuolar H+ ATPases with heterogeneous forms of Mr = 31,000 subunit have different membrane distributions in mammalian kidney.

PubMed ID: 1533641

DOI: 10.1016/s0021-9258(19)50184-3

PubMed ID: 8004105

Title: The E subunit of vacuolar H(+)-ATPase localizes close to the centromere on human chromosome 22.

PubMed ID: 8004105

DOI: 10.1093/hmg/3.2.335

PubMed ID: 8250920

Title: Cloning and tissue distribution of subunits C, D, and E of the human vacuolar H(+)-ATPase.

PubMed ID: 8250920

DOI: 10.1006/bbrc.1993.2434

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11399750

Title: Interaction between aldolase and vacuolar H+-ATPase: evidence for direct coupling of glycolysis to the ATP-hydrolyzing proton pump.

PubMed ID: 11399750

DOI: 10.1074/jbc.m008768200

PubMed ID: 12036578

Title: A human gene, ATP6E1, encoding a testis-specific isoform of H(+)-ATPase subunit E.

PubMed ID: 12036578

DOI: 10.1016/s0378-1119(02)00542-5

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 20717956

Title: Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts.

PubMed ID: 20717956

DOI: 10.1002/jcp.22388

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28065471

Title: Mutations in ATP6V1E1 or ATP6V1A cause autosomal-recessive cutis laxa.

PubMed ID: 28065471

DOI: 10.1016/j.ajhg.2016.12.010

PubMed ID: 29993276

Title: H+-ATPase B1 subunit localizes to thick ascending limb and distal convoluted tubule of rodent and human kidney.

PubMed ID: 29993276

DOI: 10.1152/ajprenal.00539.2017

PubMed ID: 32001091

Title: Structure and Roles of V-type ATPases.

PubMed ID: 32001091

DOI: 10.1016/j.tibs.2019.12.007

PubMed ID: 33065002

Title: Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.

PubMed ID: 33065002

DOI: 10.1016/j.molcel.2020.09.029

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 226
Mass: 26145
Checksum: DFD0D44E6D9AEA17
Sequence:

MALSDADVQK QIKHMMAFIE QEANEKAEEI DAKAEEEFNI EKGRLVQTQR LKIMEYYEKK 
EKQIEQQKKI QMSNLMNQAR LKVLRARDDL ITDLLNEAKQ RLSKVVKDTT RYQVLLDGLV 
LQGLYQLLEP RMIVRCRKQD FPLVKAAVQK AIPMYKIATK NDVDVQIDQE SYLPEDIAGG 
VEIYNGDRKI KVSNTLESRL DLIAQQMMPE VRGALFGANA NRKFLD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ATP6V1E1

Associated with

Other Information

Immunologic evidence that vacuolar H+ ATPases with heterogeneous forms of Mr = 31,000 subunit have different membrane distributions in mammalian kidney. PubMed ID: 1533641

The E subunit of vacuolar H(+)-ATPase localizes close to the centromere on human chromosome 22. PubMed ID: 8004105

Cloning and tissue distribution of subunits C, D, and E of the human vacuolar H(+)-ATPase. PubMed ID: 8250920

A genome annotation-driven approach to cloning the human ORFeome. PubMed ID: 15461802

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence of human chromosome 22. PubMed ID: 10591208

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Interaction between aldolase and vacuolar H+-ATPase: evidence for direct coupling of glycolysis to the ATP-hydrolyzing proton pump. PubMed ID: 11399750

A human gene, ATP6E1, encoding a testis-specific isoform of H(+)-ATPase subunit E. PubMed ID: 12036578

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Initial characterization of the human central proteome. PubMed ID: 21269460

Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts. PubMed ID: 20717956

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Mutations in ATP6V1E1 or ATP6V1A cause autosomal-recessive cutis laxa. PubMed ID: 28065471

H+-ATPase B1 subunit localizes to thick ascending limb and distal convoluted tubule of rodent and human kidney. PubMed ID: 29993276

Structure and Roles of V-type ATPases. PubMed ID: 32001091

Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly. PubMed ID: 33065002

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974