Details for: Batf

Gene ID: 53314

Symbol: Batf

Ensembl ID: ENSMUSG00000034266

Description: basic leucine zipper transcription factor, ATF-like

Associated with

  • Cytoplasm
    (GO:0005737)
  • Defense response to protozoan
    (GO:0042832)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna damage response
    (GO:0006974)
  • Dna damage response, signal transduction by p53 class mediator
    (GO:0030330)
  • Hematopoietic stem cell differentiation
    (GO:0060218)
  • Isotype switching
    (GO:0045190)
  • Lymphoid progenitor cell differentiation
    (GO:0002320)
  • Myeloid dendritic cell differentiation
    (GO:0043011)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of cytokine production
    (GO:0001819)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulator complex
    (GO:0090575)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • T-helper 2 cell differentiation
    (GO:0045064)
  • T-helper 17 cell differentiation
    (GO:0072539)
  • T-helper 17 cell lineage commitment
    (GO:0072540)

Other Information

Genular Protein ID: 2919618047

Symbol: BATF_MOUSE

Name: Basic leucine zipper transcriptional factor ATF-like

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11466704

Title: Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus.

PubMed ID: 11466704

DOI: 10.1002/1521-4141(200105)31:5<1620::aid-immu1620>3.0.co;2-3

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12444555

Title: Stat3-dependent induction of BATF in M1 mouse myeloid leukemia cells.

PubMed ID: 12444555

DOI: 10.1038/sj.onc.1205918

PubMed ID: 12809553

Title: Phosphorylation of BATF regulates DNA binding: a novel mechanism for AP-1 (activator protein-1) regulation.

PubMed ID: 12809553

DOI: 10.1042/bj20030455

PubMed ID: 12594265

Title: BATF transgenic mice reveal a role for activator protein-1 in NKT cell development.

PubMed ID: 12594265

DOI: 10.4049/jimmunol.170.5.2417

PubMed ID: 19578362

Title: The AP-1 transcription factor Batf controls T(H)17 differentiation.

PubMed ID: 19578362

DOI: 10.1038/nature08114

PubMed ID: 20421391

Title: Batf coordinates multiple aspects of B and T cell function required for normal antibody responses.

PubMed ID: 20421391

DOI: 10.1084/jem.20091548

PubMed ID: 21572431

Title: The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells.

PubMed ID: 21572431

DOI: 10.1038/ni.2037

PubMed ID: 22001828

Title: Transcription factor c-Maf mediates the TGF-beta-dependent suppression of IL-22 production in T(H)17 cells.

PubMed ID: 22001828

DOI: 10.1038/ni.2134

PubMed ID: 21873234

Title: Basic leucine zipper transcription factor, ATF-like (BATF) regulates epigenetically and energetically effector CD8 T-cell differentiation via Sirt1 expression.

PubMed ID: 21873234

DOI: 10.1073/pnas.1105133108

PubMed ID: 22385964

Title: A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage.

PubMed ID: 22385964

DOI: 10.1016/j.cell.2012.01.040

PubMed ID: 23021777

Title: A validated regulatory network for Th17 cell specification.

PubMed ID: 23021777

DOI: 10.1016/j.cell.2012.09.016

PubMed ID: 22318729

Title: STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function.

PubMed ID: 22318729

DOI: 10.1074/jbc.m111.324046

PubMed ID: 22992524

Title: Compensatory dendritic cell development mediated by BATF-IRF interactions.

PubMed ID: 22992524

DOI: 10.1038/nature11531

PubMed ID: 22992523

Title: BATF-JUN is critical for IRF4-mediated transcription in T cells.

PubMed ID: 22992523

DOI: 10.1038/nature11530

PubMed ID: 22983707

Title: A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes.

PubMed ID: 22983707

DOI: 10.1126/science.1228309

Sequence Information:

  • Length: 125
  • Mass: 14065
  • Checksum: A23B00D6E0827938
  • Sequence:
  • MPHSSDSSDS SFSRSPPPGK QDSSDDVRKV QRREKNRIAA QKSRQRQTQK ADTLHLESED 
    LEKQNAALRK EIKQLTEELK YFTSVLSSHE PLCSVLASGT PSPPEVVYSA HAFHQPHISS 
    PRFQP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.