Usp2 | ENSMUSG00000032010 | NCBI 53376

Details for: Usp2

Gene ID: 53376

Symbol: Usp2

Ensembl ID: ENSMUSG00000032010

Description: ubiquitin specific peptidase 2

Associated with

Death receptor signaling
(R-MMU-73887)
Deubiquitination
(R-MMU-5688426)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Regulation of tnfr1 signaling
(R-MMU-5357905)
Regulation of tp53 activity
(R-MMU-5633007)
Regulation of tp53 degradation
(R-MMU-6804757)
Regulation of tp53 expression and degradation
(R-MMU-6806003)
Rna polymerase ii transcription
(R-MMU-73857)
Signal transduction
(R-MMU-162582)
Tnfr1-induced nf-kappa-b signaling pathway
(R-MMU-5357956)
Tnfr1-induced proapoptotic signaling
(R-MMU-5357786)
Tnf signaling
(R-MMU-75893)
Transcriptional regulation by tp53
(R-MMU-3700989)
Ub-specific processing proteases
(R-MMU-5689880)
Centrosome
(GO:0005813)
Circadian behavior
(GO:0048512)
Circadian regulation of gene expression
(GO:0032922)
Cyclin binding
(GO:0030332)
Cysteine-type deubiquitinase activity
(GO:0004843)
Cytoplasm
(GO:0005737)
Entrainment of circadian clock by photoperiod
(GO:0043153)
Identical protein binding
(GO:0042802)
Locomotor rhythm
(GO:0045475)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Muscle organ development
(GO:0007517)
Negative regulation of calcium ion transport
(GO:0051926)
Negative regulation of skeletal muscle tissue development
(GO:0048642)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of mitotic cell cycle
(GO:0045931)
Positive regulation of skeletal muscle tissue development
(GO:0048643)
Protein binding
(GO:0005515)
Protein deubiquitination
(GO:0016579)
Protein stabilization
(GO:0050821)
Proteolysis
(GO:0006508)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

41 kDa ubiquitin-specific protease

Genular Protein ID: 2898447796

Symbol: UBP2_MOUSE

Name: 41 kDa ubiquitin-specific protease

UniProtKB Accession Codes:

O88623 Q6X4T9 Q6X4U1 Q8VD74 Q9JJ87

Database IDs:

Citations:

PubMed ID: 14686789

Title: Gene structure, alternate splicing, tissue distribution, cellular localization, and developmental expression pattern of mouse deubiquitinating enzyme isoforms Usp2-45 and Usp2-69.

PubMed ID: 14686789

DOI: 10.3727/000000003108749053

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 23213472

Title: Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2.

PubMed ID: 23213472

DOI: 10.1242/bio.20121990

PubMed ID: 25238854

Title: USP2 regulates the intracellular localization of per1 and circadian gene expression.

PubMed ID: 25238854

DOI: 10.1177/0748730414544741

PubMed ID: 26756164

Title: USP2-45 is a circadian clock output effector regulating calcium absorption at the post-translational level.

PubMed ID: 26756164

DOI: 10.1371/journal.pone.0145155

Sequence Information:

Length: 619
Mass: 69525
Checksum: 93A6F2B9269316F8
Sequence:

MSQLSSTLKR YTESSRYTDA PYAKPGYGTY TPSSYGANLA ASFLEKEKLG FKPVSPTSFL 
PRPRTYGPSS ILDCDRGRPL LRSDIIGSSK RSESQTRGNE RPSGSGLNGG SGFSYGVSSN 
SLSYLPMNAR DQGVTLSQKK SNSQSDLARD FSSLRTSDGY RTSDGYRTSE GFRIDPGNLG 
RSPMLARTRK ELCALQGLYQ AASRSEYLTD YLENYGRKGS APQVLTQAPP PSRVPEVLSP 
TYRPSGRYTL WEKSKGQASG PSRSSSPGRD TMNSKSAQGL AGLRNLGNTC FMNSILQCLS 
NTRELRDYCL QRLYMRDLGH TSSAHTALME EFAKLIQTIW TSSPNDVVSP SEFKTQIQRY 
APRFMGYNQQ DAQEFLRFLL DGLHNEVNRV AARPKASPET LDHLPDEEKG RQMWRKYLER 
EDSRIGDLFV GQLKSSLTCT DCGYCSTVFD PFWDLSLPIA KRGYPEVTLM DCMRLFTKED 
ILDGDEKPTC CRCRARKRCI KKFSVQRFPK ILVLHLKRFS ESRIRTSKLT TFVNFPLRDL 
DLREFASENT NHAVYNLYAV SNHSGTTMGG HYTAYCRSPV TGEWHTFNDS SVTPMSSSQV 
RTSDAYLLFY ELASPPSRM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Usp2

Associated with

Other Information

Gene structure, alternate splicing, tissue distribution, cellular localization, and developmental expression pattern of mouse deubiquitinating enzyme isoforms Usp2-45 and Usp2-69. PubMed ID: 14686789

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2. PubMed ID: 23213472

USP2 regulates the intracellular localization of per1 and circadian gene expression. PubMed ID: 25238854