Details for: Corin

Gene ID: 53419

Symbol: Corin

Ensembl ID: ENSMUSG00000005220

Description: corin, serine peptidase

Associated with

Other Information

Genular Protein ID: 432878796

Symbol: CORIN_MOUSE

Name: Atrial natriuretic peptide-converting enzyme

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9756624

Title: A novel low-density lipoprotein receptor-related protein with type II membrane protein-like structure is abundant in heart.

PubMed ID: 9756624

DOI: 10.1093/oxfordjournals.jbchem.a022180

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11884416

Title: Processing of pro-atrial natriuretic peptide by corin in cardiac myocytes.

PubMed ID: 11884416

DOI: 10.1074/jbc.m201503200

PubMed ID: 15637153

Title: Hypertension in mice lacking the proatrial natriuretic peptide convertase corin.

PubMed ID: 15637153

DOI: 10.1073/pnas.0407234102

PubMed ID: 20613715

Title: Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases.

PubMed ID: 20613715

DOI: 10.1038/ki.2010.197

PubMed ID: 21518754

Title: Human corin isoforms with different cytoplasmic tails that alter cell surface targeting.

PubMed ID: 21518754

DOI: 10.1074/jbc.m110.217570

PubMed ID: 21903139

Title: Corin-deficient W-sh mice poorly tolerate increased cardiac afterload.

PubMed ID: 21903139

DOI: 10.1016/j.regpep.2011.08.006

PubMed ID: 22418978

Title: Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice.

PubMed ID: 22418978

DOI: 10.1038/ki.2012.41

PubMed ID: 22437503

Title: Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy.

PubMed ID: 22437503

DOI: 10.1038/nature10897

Sequence Information:

  • Length: 1113
  • Mass: 123006
  • Checksum: D6D002204779F8EA
  • Sequence:
  • MGRVSFSVRV SSVRRARCSC PGRCYLSCRV PPTTALRALN GLGCAGVPGE TAGGAVGPGP 
    LGTRGFLSGS KFQAPGSWKD CFGAPPAPDV LRADRSVGEG CPQKLVTANL LRFLLLVLIP 
    CICALIVLLA ILLSFVGTLK RVYFKSNDSE PLVTDGEARV PGVIPVNTVY YENTGAPSLP 
    PSQSTPAWTP RAPSPEDQSH RNTSTCMNIT HSQCQILPYH STLAPLLPIV KNMDMEKFLK 
    FFTYLHRLSC YQHILLFGCS LAFPECVVDG DDRHGLLPCR SFCEAAKEGC ESVLGMVNSS 
    WPDSLRCSQF RDHTETNSSV RKSCFSLQQE HGKQSLCGGG ESFLCTSGLC VPKKLQCNGY 
    NDCDDWSDEA HCNCSKDLFH CGTGKCLHYS LLCDGYDDCG DLSDEQNCDC NLTKEHRCGD 
    GRCIAAEWVC DGDHDCVDKS DEVNCSCHSQ GLVECRSGQC IPSTFQCDGD EDCKDGSDEE 
    NCSDSQTPCP EGEQGCLGSS CVESCAGSSL CDSDSSLSNC SQCEPITLEL CMNLPYNHTH 
    YPNYLGHRTQ KEASISWESS LFPALVQTNC YKYLMFFACT ILVPKCDVNT GQRIPPCRLL 
    CEHSKERCES VLGIVGLQWP EDTDCNQFPE ESSDNQTCLL PNEDVEECSP SHFKCRSGRC 
    VLGSRRCDGQ ADCDDDSDEE NCGCKERALW ECPFNKQCLK HTLICDGFPD CPDSMDEKNC 
    SFCQDNELEC ANHECVPRDL WCDGWVDCSD SSDEWGCVTL SKNGNSSSLL TVHKSAKEHH 
    VCADGWRETL SQLACKQMGL GEPSVTKLIP GQEGQQWLRL YPNWENLNGS TLQELLVYRH 
    SCPSRSEISL LCSKQDCGRR PAARMNKRIL GGRTSRPGRW PWQCSLQSEP SGHICGCVLI 
    AKKWVLTVAH CFEGREDADV WKVVFGINNL DHPSGFMQTR FVKTILLHPR YSRAVVDYDI 
    SVVELSDDIN ETSYVRPVCL PSPEEYLEPD TYCYITGWGH MGNKMPFKLQ EGEVRIIPLE 
    QCQSYFDMKT ITNRMICAGY ESGTVDSCMG DSGGPLVCER PGGQWTLFGL TSWGSVCFSK 
    VLGPGVYSNV SYFVGWIERQ IYIQTFLQKK SQG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.