Details for: ATP6V0A1
Gene ID: 535
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: ATP6V0A1
Ensembl ID: ENSG00000033627
Description: ATPase H+ transporting V0 subunit a1
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
-
CSI 37.85rCSI 60.87%PRS 47.64
-
CSI 36.13rCSI 60.64%PRS 45.68
-
CSI 30.96rCSI 39.92%PRS 46.97
-
CSI 27.66rCSI 33.04%PRS 45.49
-
CSI 26.11rCSI 63.47%PRS 44.17
-
CSI 24.8rCSI 43.81%PRS 44.81
-
CSI 24.56rCSI 30.55%PRS 43.86
-
CSI 21.41rCSI 47.29%PRS 50.25
-
CSI 21.19rCSI 66.22%PRS 47.36
-
CSI 17.31rCSI 62.28%PRS 44.02
-
CSI 16.47rCSI 51.5%PRS 49.82
-
CSI 16.31rCSI 61.64%PRS 46.37
-
CSI 14.28rCSI 38.04%PRS 53.41
-
CSI 14.07rCSI 48.18%PRS 52.83
-
CSI 13.58rCSI 32.47%PRS 51.26
-
CSI 10.81rCSI 63.68%PRS 46.82
-
CSI 9.92rCSI 26.34%PRS 74.88
-
CSI 9.69rCSI 22.15%PRS 64.27
-
CSI 9.67rCSI 14.78%PRS 68.55
-
CSI 8.76rCSI 64.42%PRS 50.65
-
CSI 8.69rCSI 9.1%PRS 67.86
-
CSI 8.56rCSI 6.76%PRS 51.15
-
CSI 7.89rCSI 29.78%PRS 49.94
-
CSI 7.77rCSI 16.86%PRS 51.85
-
CSI 7.58rCSI 10.36%PRS 65.76
-
CSI 7.1rCSI 10.43%PRS 57.49
-
CSI 6.8rCSI 29.86%PRS 60.62
-
CSI 6.51rCSI 5.66%PRS 75
-
CSI 6.47rCSI 8.05%PRS 74.93
-
CSI 6.29rCSI 10.14%PRS 67.42
-
CSI 6.24rCSI 7.59%PRS 71.74
-
CSI 6.14rCSI 16.17%PRS 81.61
-
CSI 6.13rCSI 9.78%PRS 56.6
-
CSI 6.08rCSI 9.79%PRS 53.81
-
CSI 5.73rCSI 6.86%PRS 79.97
-
CSI 5.64rCSI 7.55%PRS 64.53
-
CSI 5.47rCSI 10.42%PRS 78.69
-
CSI 5.41rCSI 9.69%PRS 63.43
-
CSI 5.3rCSI 5.21%PRS 66.98
-
CSI 5.3rCSI 7.25%PRS 57.33
-
CSI 5.21rCSI 17.12%PRS 51.01
-
CSI 5.21rCSI 13.58%PRS 67.27
-
CSI 5.13rCSI 4.56%PRS 62.22
-
CSI 5.13rCSI 6.53%PRS 70.72
-
CSI 5.09rCSI 4.14%PRS 64.62
-
CSI 5.08rCSI 8.9%PRS 56.2
-
CSI 5.01rCSI 28.88%PRS 62.59
-
CSI 4.98rCSI 5.34%PRS 64.06
-
CSI 4.71rCSI 40.59%PRS 51.2
-
CSI 4.6rCSI 11.99%PRS 63.95
-
CSI 4.58rCSI 51.47%PRS 81.33
-
CSI 4.56rCSI 64.71%PRS 55.17
-
CSI 4.51rCSI 7.95%PRS 60.86
-
CSI 4.49rCSI 16.83%PRS 56.18
-
CSI 4.43rCSI 12.22%PRS 59.59
-
CSI 4.41rCSI 9.71%PRS 68.39
-
CSI 4.36rCSI 9.94%PRS 55.79
-
CSI 4.32rCSI 17.21%PRS 76.16
-
CSI 4.14rCSI 5.75%PRS 62.78
-
CSI 4.12rCSI 9.51%PRS 52.93
-
CSI 4.11rCSI 64.75%PRS 68.74
-
CSI 4.03rCSI 12.9%PRS 61.29
-
CSI 4.03rCSI 19.3%PRS 64.15
-
CSI 3.92rCSI 7.87%PRS 53.28
-
CSI 3.76rCSI 3.5%PRS 64.92
-
CSI 3.69rCSI 12.36%PRS 49.08
-
CSI 3.65rCSI 8.16%PRS 72.23
-
CSI 3.62rCSI 11.16%PRS 72.26
-
CSI 3.62rCSI 8.63%PRS 72.42
-
CSI 3.56rCSI 4.86%PRS 55.92
-
CSI 3.55rCSI 4.28%PRS 73.12
-
CSI 3.54rCSI 7.27%PRS 54.02
-
CSI 3.51rCSI 4.51%PRS 61.33
-
CSI 3.5rCSI 7.95%PRS 67.82
-
CSI 3.45rCSI 14.08%PRS 58.01
-
CSI 3.45rCSI 70.34%PRS 54.87
-
CSI 3.45rCSI 3.18%PRS 65.81
-
CSI 3.44rCSI 5.12%PRS 65.66
-
CSI 3.44rCSI 2.55%PRS 56.76
-
CSI 3.41rCSI 7.99%PRS 68.33
-
CSI 3.39rCSI 6.1%PRS 57.51
-
CSI 3.36rCSI 68.45%PRS 56.34
-
CSI 3.35rCSI 4.58%PRS 70.24
-
CSI 3.34rCSI 4.2%PRS 76.22
-
CSI 3.34rCSI 6.25%PRS 52.41
-
CSI 3.31rCSI 10.61%PRS 69
-
CSI 3.3rCSI 6.22%PRS 74.74
-
CSI 3.28rCSI 2.18%PRS 67.47
-
CSI 3.27rCSI 9.31%PRS 62.17
-
CSI 3.27rCSI 10.59%PRS 64.2
-
CSI 3.21rCSI 8.48%PRS 72.97
-
CSI 3.18rCSI 3.94%PRS 61.02
-
CSI 3.18rCSI 19.86%PRS 55.99
-
CSI 3.16rCSI 7.54%PRS 64.81
-
CSI 3.16rCSI 5.2%PRS 69.62
-
CSI 3.13rCSI 3.61%PRS 57.18
-
CSI 3.11rCSI 7.71%PRS 62.76
-
CSI 3.02rCSI 8.91%PRS 67.03
-
CSI 2.95rCSI 11.48%PRS 68.41
-
CSI 2.94rCSI 5.08%PRS 54.33
-
CSI 0.1rCSI 1.9%PRS 77.5%
-
CSI 0.3rCSI 3.5%PRS 74.7%
-
CSI 0.5rCSI 2.5%PRS 75.8%
-
CSI 0.5rCSI 1.4%PRS 76.4%
-
CSI 0.5rCSI 2.6%PRS 61.2%
-
CSI 0.6rCSI 3.3%PRS 73.4%
-
CSI 0.7rCSI 4.1%PRS 58.7%
-
CSI 0.7rCSI 1.4%PRS 67.3%
-
CSI 0.7rCSI 3.5%PRS 79.9%
-
CSI 0.8rCSI 1.6%PRS 74.9%
-
CSI 0.8rCSI 7.1%PRS 51.2%
-
CSI 0.8rCSI 3.4%PRS 76.0%
-
CSI 0.9rCSI 3.4%PRS 63.0%
-
CSI 0.9rCSI 5.7%PRS 61.1%
-
CSI 0.9rCSI 5.3%PRS 81.9%
-
CSI 0.9rCSI 5.5%PRS 46.4%
-
CSI 0.9rCSI 6.9%PRS 74.7%
-
CSI 0.9rCSI 4.1%PRS 64.1%
-
CSI 1.0rCSI 4.6%PRS 79.9%
-
CSI 1.0rCSI 1.5%PRS 79.6%
-
CSI 1.0rCSI 2.6%PRS 53.6%
-
CSI 1.0rCSI 2.5%PRS 72.8%
-
CSI 1.0rCSI 1.4%PRS 70.8%
-
CSI 1.1rCSI 2.0%PRS 81.7%
-
CSI 1.1rCSI 2.7%PRS 71.4%
-
CSI 1.1rCSI 3.2%PRS 75.6%
-
CSI 1.2rCSI 3.7%PRS 62.2%
-
CSI 1.2rCSI 3.1%PRS 71.2%
-
CSI 1.2rCSI 4.4%PRS 72.3%
-
CSI 1.2rCSI 5.2%PRS 76.2%
-
CSI 1.3rCSI 2.0%PRS 66.7%
-
CSI 1.3rCSI 5.0%PRS 78.1%
-
CSI 1.3rCSI 3.4%PRS 61.2%
-
CSI 1.4rCSI 2.4%PRS 72.4%
-
CSI 1.4rCSI 7.4%PRS 78.7%
-
CSI 1.4rCSI 2.1%PRS 68.8%
-
CSI 1.5rCSI 2.9%PRS 79.6%
-
CSI 1.5rCSI 4.1%PRS 75.1%
-
CSI 1.5rCSI 3.0%PRS 61.6%
-
CSI 1.5rCSI 12.4%PRS 57.6%
-
CSI 1.6rCSI 2.0%PRS 74.8%
-
CSI 1.6rCSI 2.3%PRS 67.4%
-
CSI 1.6rCSI 3.5%PRS 72.1%
-
CSI 1.6rCSI 1.9%PRS 54.6%
-
CSI 1.7rCSI 3.5%PRS 62.8%
-
CSI 1.7rCSI 9.3%PRS 49.3%
-
CSI 1.7rCSI 2.4%PRS 73.5%
-
CSI 1.7rCSI 3.1%PRS 55.9%
-
CSI 1.7rCSI 2.7%PRS 68.5%
-
CSI 1.8rCSI 7.8%PRS 48.2%
-
CSI 1.8rCSI 5.1%PRS 65.6%
-
CSI 1.8rCSI 4.7%PRS 55.2%
-
CSI 1.8rCSI 6.8%PRS 54.9%
-
CSI 1.8rCSI 1.9%PRS 62.4%
-
CSI 1.8rCSI 4.1%PRS 46.4%
-
CSI 1.8rCSI 1.4%PRS 65.1%
-
CSI 1.8rCSI 4.1%PRS 62.4%
-
CSI 1.8rCSI 2.9%PRS 56.7%
-
CSI 1.9rCSI 1.7%PRS 61.3%
-
CSI 1.9rCSI 3.6%PRS 78.1%
-
CSI 1.9rCSI 2.9%PRS 62.7%
-
CSI 1.9rCSI 8.8%PRS 82.0%
-
CSI 1.9rCSI 1.7%PRS 52.2%
-
CSI 2.0rCSI 9.7%PRS 75.2%
-
CSI 2.0rCSI 8.4%PRS 57.3%
-
CSI 2.0rCSI 8.7%PRS 54.4%
-
CSI 2.0rCSI 2.6%PRS 69.0%
-
CSI 2.0rCSI 15.1%PRS 79.5%
-
CSI 2.1rCSI 1.7%PRS 65.8%
-
CSI 2.1rCSI 2.0%PRS 63.7%
-
CSI 2.1rCSI 3.8%PRS 78.9%
-
CSI 2.1rCSI 2.7%PRS 77.6%
-
CSI 2.1rCSI 3.0%PRS 53.9%
-
CSI 2.1rCSI 6.1%PRS 53.8%
-
CSI 2.1rCSI 2.0%PRS 73.3%
-
CSI 2.2rCSI 1.8%PRS 63.7%
-
CSI 2.3rCSI 3.2%PRS 60.6%
-
CSI 2.3rCSI 5.1%PRS 80.7%
-
CSI 2.3rCSI 5.9%PRS 63.3%
-
CSI 2.3rCSI 2.5%PRS 68.0%
-
CSI 2.3rCSI 9.4%PRS 63.1%
-
CSI 2.3rCSI 3.6%PRS 60.8%
-
CSI 2.3rCSI 3.6%PRS 65.0%
-
CSI 2.3rCSI 3.6%PRS 73.5%
-
CSI 2.4rCSI 3.4%PRS 66.4%
-
CSI 2.4rCSI 3.3%PRS 70.5%
-
CSI 2.5rCSI 4.0%PRS 75.2%
-
CSI 2.5rCSI 3.9%PRS 71.4%
-
CSI 2.5rCSI 3.1%PRS 65.9%
-
CSI 2.5rCSI 2.6%PRS 77.9%
-
CSI 2.5rCSI 6.6%PRS 59.3%
-
CSI 2.6rCSI 4.0%PRS 73.5%
-
CSI 2.6rCSI 2.8%PRS 60.7%
-
CSI 2.7rCSI 5.8%PRS 76.3%
-
CSI 2.7rCSI 5.4%PRS 43.2%
-
CSI 2.7rCSI 3.4%PRS 56.5%
-
CSI 2.7rCSI 2.1%PRS 66.7%
-
CSI 2.8rCSI 4.0%PRS 79.9%
-
CSI 2.8rCSI 8.0%PRS 76.9%
-
CSI 2.9rCSI 69.0%PRS 45.5%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 1361359308
Symbol: VPP1_HUMAN
Name: V-type proton ATPase 116 kDa subunit a 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 12643545
Title: Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.
PubMed ID: 12643545
DOI: 10.1021/pr025562r
PubMed ID: 17081065
Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.
PubMed ID: 17081065
DOI: 10.1021/pr060363j
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 28024296
Title: mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide.
PubMed ID: 28024296
DOI: 10.1038/nature21034
PubMed ID: 33065002
Title: Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
PubMed ID: 33065002
PubMed ID: 34909687
Title: Variants in ATP6V0A1 cause progressive myoclonus epilepsy and developmental and epileptic encephalopathy.
PubMed ID: 34909687
PubMed ID: 33833240
Title: ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H+-ATPases is essential for brain development in humans and mice.
PubMed ID: 33833240
Sequence Information:
- Length: 837
- Mass: 96413
- Checksum: 80E4842CF6ADEE44
- Sequence:
MGELFRSEEM TLAQLFLQSE AAYCCVSELG ELGKVQFRDL NPDVNVFQRK FVNEVRRCEE MDRKLRFVEK EIRKANIPIM DTGENPEVPF PRDMIDLEAN FEKIENELKE INTNQEALKR NFLELTELKF ILRKTQQFFD EMADPDLLEE SSSLLEPSEM GRGTPLRLGF VAGVINRERI PTFERMLWRV CRGNVFLRQA EIENPLEDPV TGDYVHKSVF IIFFQGDQLK NRVKKICEGF RASLYPCPET PQERKEMASG VNTRIDDLQM VLNQTEDHRQ RVLQAAAKNI RVWFIKVRKM KAIYHTLNLC NIDVTQKCLI AEVWCPVTDL DSIQFALRRG TEHSGSTVPS ILNRMQTNQT PPTYNKTNKF TYGFQNIVDA YGIGTYREIN PAPYTIITFP FLFAVMFGDF GHGILMTLFA VWMVLRESRI LSQKNENEMF STVFSGRYII LLMGVFSMYT GLIYNDCFSK SLNIFGSSWS VRPMFTYNWT EETLRGNPVL QLNPALPGVF GGPYPFGIDP IWNIATNKLT FLNSFKMKMS VILGIIHMLF GVSLSLFNHI YFKKPLNIYF GFIPEIIFMT SLFGYLVILI FYKWTAYDAH TSENAPSLLI HFINMFLFSY PESGYSMLYS GQKGIQCFLV VVALLCVPWM LLFKPLVLRR QYLRRKHLGT LNFGGIRVGN GPTEEDAEII QHDQLSTHSE DADEPSEDEV FDFGDTMVHQ AIHTIEYCLG CISNTASYLR LWALSLAHAQ LSEVLWTMVI HIGLSVKSLA GGLVLFFFFT AFATLTVAIL LIMEGLSAFL HALRLHWVEF QNKFYSGTGF KFLPFSFEHI REGKFEE
Genular Protein ID: 3091214484
Symbol: Q53X12_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 831
- Mass: 95751
- Checksum: A3D85B27CA2AC55E
- Sequence:
MGELFRSEEM TLAQLFLQSE AAYCCVSELG ELGKVQFRDL NPDVNVFQRK FVNEVRRCEE MDRKLRFVEK EIRKANIPIM DTGENPEVPF PRDMIDLEAN FEKIENELKE INTNQEALKR NFLELTELKF ILRKTQQFFD EMADPDLLEE SSSLLEPSEM GRGTPLRLGF VAGVINRERI PTFERMLWRV CRGNVFLRQA EIENPLEDPV TGDYVHKSVF IIFFQGDQLK NRVKKICEGF RASLYPCPET PQERKEMASG VNTRIDDLQM VLNQTEDHRQ RVLQAAAKNI RVWFIKVRKM KAIYHTLNLC NIDVTQKCLI AEVWCPVTDL DSIQFALRRG TEHSGSTVPS ILNRMQTNQT PPTYNKTNKF TYGFQNIVDA YGIGTYREIN PAPYTIITFP FLFAVMFGDF GHGILMTLFA VWMVLRESRI LSQKNENEMF STVFSGRYII LLMGVFSMYT GLIYNDCFSK SLNIFGSSWS VRPMFTYNWT EETLRGNPVL QLNPALPGVF GGPYPFGIDP IWNIATNKLT FLNSFKMKMS VILGIIHMLF GVSLSLFNHI YFKKPLNIYF GFIPEIIFMT SLFGYLVILI FYKWTAYDAH TSENAPSLLI HFINMFLFSY PESGYSMLYS GQKGIQCFLV VVALLCVPWM LLFKPLVLRR QYLRRKHLGT LNFGGIRVGN GPTEEDAEII QHDQLSTHSE DADEFDFGDT MVHQAIHTIE YCLGCISNTA SYLRLWALSL AHAHVSEVLW TMVIHIGLSV KSLAGGLVLF FFFTAFATLT VAILLIMEGL SAFLHALRLH WVEFQNKFYS GTGFKFLPFS FEHIREGKFE E
Genular Protein ID: 3909198861
Symbol: Q53ET5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8125298
Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
PubMed ID: 8125298
PubMed ID: 9373149
Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
PubMed ID: 9373149
Sequence Information:
- Length: 831
- Mass: 95804
- Checksum: 0C84BE64B8CC0D03
- Sequence:
MGELFRSEEM TLAQLFLQSE AAYCCVSELG ELGKVQFRDL NPYVNVFQRK FVNEVRRCEE MDRKLRFVEK EIRKANIPIM DTGENPEVPF PRDMIDLEAN FEKIENELKE INTNQEALKR NFLELTELKF ILRKTQQFFD EMADPDLLEE SSSLLEPSEM GRGTPLRLGF VAGVINRERI PTFERMLWRV CRGNVFLRQA EIENPLEDPV TGDYVHKSVF IIFFQGDQLK NRVKKICEGF RASLYPCPET PQERKEMASG VNTRIDDLQM VLNQTEDHRQ RVLQAAAKNI RVWFIKVRKM KAIYHTLNLC NIDVTQKCLI AEVWCPVTDL DSIQFALRRG TEHSGSTVPS ILNRMQTNQT PPTYNKTNKF TYGFQNIVDA YGIGTYREIN PAPYTIITFP FLFAVMFGDF GHGILMTLFA VWMVLRESRI LSQKNENEMF STVFSGRYII LLMGVFSMYT GLIYNDCFSK SLNIFGSSWS VRPMFTYNWT EETLRGNPVL QLNPALPGVF GGPYPFGIDP IWNIATNKLT FLNSFKMKMS VILGIIHMLF GVSLSLFNHI YFKKPLNIYF GFIPEIIFMT SLFGYLVILI FYKWTAYDAH TSENAPSLLI HFINMFLFSY PESGYSMLYS GQKGIQCFLV VVALLCVPWM LLFKPLVLRR QYLRRKHLGT LNFGGIRVGN GPTEEDAEII QHDQLSTHSE DADEFDFGDT MVHQAIHTIE YCLGCISNTA SYLRLWALSL AHAQLSEVLW TMVIHIGLSV KSLAGGLVLF FFFTAFATLT VAILLIMEGL SAFLHALRLH WVEFQNKFYS GTGFKFLPFS FEHIREGKFE E
Genular Protein ID: 2554519332
Symbol: Q5CZH6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 838
- Mass: 96603
- Checksum: 20E56A8DA482FDB7
- Sequence:
MGELFRSEEM TLAQLFLQSE AAYCCVSELG ELGKVQFRDL NPDVNVFQRK FVNEVRRCEE MDRKLRFVEK EIRKANIPIM DTGENPEVPF PRDMIDLEAN FEKIENELKE INTNQEALKR NFLELTELKF ILRKTQQFFD EAELHHQQMA DPDLLEESSS LLEPSEMGRG TPLRLGFVAG VINRERIPTF ERMLWRVCRG NVFLRQAEIE NPLEDPVTGD YVHKSVFIIF FQGDQLKNRV KKICEGFRAS LYPCPETPQE RKEMASGVST RIDDLQMVLN QMEDHRQRVL QAAAKNIRVW FIKVRKMKAI YHTLNLCNID VTQKCLIAEV WCPVTDLDSI QFALRRGTEH SGSTVPSILN RMQTNQTPPT YNKTNKFTYG FQNIVDAYGI GTYREINPAP YTIITFPFLF AVMFGDFGHG ILMTLFAVWM VLRESRILSQ KNENEMFSTV FSGRYIILLM GVFSMYTGLI YNDCFSKSLN IFGSSWSVRP MFTYNWTEET LRGNPVLQLN PALPGVFGGP YPFGIDPIWN IATNKLTFLN SFKMKMSVIL GIIHMLFGVS LSLFNHIYFK KPLNIYFGFI PEIIFMTSLF GYLVILIFYK WTAYDAHTSE NAPSLLIHFI NMFLFSYPES GYSMLYSGQK GIQCFLVVVA LLCVPWMLLF KPLVLRRQYL RRKHLGTLNF GGIRVGNGPT EEDAEIIQHD QLSTHSEDAD EFDFGDTMVH QAIHTIEYCL GCISNTASYL RLWALSLAHA QLSEVLWTMV IHIGLSVKSL AGGLVLFFFF TAFATLTVAI LLIMEGLSAF LHALRLHWVE FQNKFYSGTG FKFLPFSFEH IREGKFEE