Details for: ATP6V0A1

Gene ID: 535

Symbol: ATP6V0A1

Ensembl ID: ENSG00000033627

Description: ATPase H+ transporting V0 subunit a1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 373.3962
    Cell Significance Index: -58.0800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 248.4591
    Cell Significance Index: -63.0200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 146.9604
    Cell Significance Index: -60.5400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 124.5517
    Cell Significance Index: -50.6000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 116.2553
    Cell Significance Index: -59.8000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 53.1242
    Cell Significance Index: -50.7200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 50.7399
    Cell Significance Index: -62.5600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 18.4408
    Cell Significance Index: -56.6400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.3961
    Cell Significance Index: -64.7000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 14.7538
    Cell Significance Index: -32.2900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 3.6164
    Cell Significance Index: 43.1100
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 3.4549
    Cell Significance Index: 26.6300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.5976
    Cell Significance Index: 66.7700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.5820
    Cell Significance Index: 517.9500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.5393
    Cell Significance Index: 31.5000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.1760
    Cell Significance Index: 137.1500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.0890
    Cell Significance Index: 749.2800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.0274
    Cell Significance Index: 1402.2500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.6396
    Cell Significance Index: 43.7800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.5598
    Cell Significance Index: 95.8700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.5169
    Cell Significance Index: 301.0400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.4828
    Cell Significance Index: 77.8500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.3081
    Cell Significance Index: 57.8600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.2647
    Cell Significance Index: 27.4000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.2570
    Cell Significance Index: 35.8700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.2504
    Cell Significance Index: 84.0800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.2376
    Cell Significance Index: 29.6800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.1955
    Cell Significance Index: 45.2700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.0934
    Cell Significance Index: 49.5600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8079
    Cell Significance Index: 87.8800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6561
    Cell Significance Index: 106.7200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.5963
    Cell Significance Index: 14.5500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5445
    Cell Significance Index: 32.6900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.4770
    Cell Significance Index: 24.8500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4548
    Cell Significance Index: 410.6900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4439
    Cell Significance Index: 34.0700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4034
    Cell Significance Index: 39.9100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3594
    Cell Significance Index: 196.2900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.3488
    Cell Significance Index: 12.2600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3327
    Cell Significance Index: 23.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.3106
    Cell Significance Index: 584.8300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2859
    Cell Significance Index: 4.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2291
    Cell Significance Index: 41.3100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1987
    Cell Significance Index: 5.7300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1897
    Cell Significance Index: 23.3200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1897
    Cell Significance Index: 26.0500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1682
    Cell Significance Index: 74.3500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1631
    Cell Significance Index: 31.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0689
    Cell Significance Index: 43.7600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0659
    Cell Significance Index: 29.9000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0656
    Cell Significance Index: 1.8800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0596
    Cell Significance Index: 81.0000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0405
    Cell Significance Index: 74.6800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0338
    Cell Significance Index: 52.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0212
    Cell Significance Index: 1.1900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0168
    Cell Significance Index: 2.1700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0250
    Cell Significance Index: -18.5300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0459
    Cell Significance Index: -28.6900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0486
    Cell Significance Index: -35.6000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0664
    Cell Significance Index: -50.2700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0785
    Cell Significance Index: -13.4100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0815
    Cell Significance Index: -45.9800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0833
    Cell Significance Index: -10.6800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1208
    Cell Significance Index: -13.8500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1479
    Cell Significance Index: -31.1500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1582
    Cell Significance Index: -4.4200
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.1777
    Cell Significance Index: -2.3700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1920
    Cell Significance Index: -55.2300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2082
    Cell Significance Index: -30.2600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2127
    Cell Significance Index: -24.7900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2167
    Cell Significance Index: -22.1400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2559
    Cell Significance Index: -19.0700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2841
    Cell Significance Index: -6.2200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3120
    Cell Significance Index: -36.8000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3413
    Cell Significance Index: -35.5400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3853
    Cell Significance Index: -43.9900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3919
    Cell Significance Index: -18.2700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.4390
    Cell Significance Index: -11.9500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.4404
    Cell Significance Index: -22.8800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.4698
    Cell Significance Index: -22.0800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5561
    Cell Significance Index: -39.3300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.6031
    Cell Significance Index: -7.5200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.6055
    Cell Significance Index: -12.5600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6271
    Cell Significance Index: -13.3600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6915
    Cell Significance Index: -54.7700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.7813
    Cell Significance Index: -10.6600
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.8747
    Cell Significance Index: -11.0400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.8927
    Cell Significance Index: -57.5900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.8980
    Cell Significance Index: -19.0600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.9023
    Cell Significance Index: -9.8300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.9075
    Cell Significance Index: -18.2200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.9966
    Cell Significance Index: -31.7400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.0086
    Cell Significance Index: -33.0200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.0246
    Cell Significance Index: -21.9000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.0286
    Cell Significance Index: -63.0700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.0312
    Cell Significance Index: -20.3900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -1.0958
    Cell Significance Index: -16.4200
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -1.0995
    Cell Significance Index: -17.7400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.1365
    Cell Significance Index: -36.4000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.1399
    Cell Significance Index: -30.5500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Proton-pumping ATPase**: The ATP6V0A1 gene encodes a V-type proton-transporting ATPase, a type of enzyme that pumps protons across cellular membranes, generating a proton gradient. 2. **Acidification**: The V0 subunit alpha 1 is responsible for acidifying various cellular compartments, including lysosomes, vacuoles, and secretory granules. 3. **Regulation of immune response**: The ATP6V0A1 gene is involved in regulating the immune response, particularly in the context of innate immunity. 4. **Neuronal expression**: The gene is significantly expressed in inhibitory interneurons, GABAergic cortical interneurons, and other specialized neural cells. **Pathways and Functions** 1. **Endosomal acidification**: The V0 subunit alpha 1 regulates the acidification of endosomes, which is essential for protein degradation, sorting, and recycling. 2. **Lysosomal acidification**: The gene is involved in regulating the acidification of lysosomes, which is crucial for protein degradation, autophagy, and immune response. 3. **Immune system**: The ATP6V0A1 gene is involved in regulating the immune response, particularly in the context of innate immunity. 4. **Signal transduction**: The gene is involved in regulating signal transduction pathways, including those mediated by insulin receptors and receptor tyrosine kinases. 5. **Protein binding**: The V0 subunit alpha 1 interacts with various proteins, including those involved in protein degradation, sorting, and recycling. **Clinical Significance** 1. **Neurological disorders**: Mutations in the ATP6V0A1 gene have been associated with neurological disorders, including epilepsy, schizophrenia, and autism spectrum disorder. 2. **Immune system dysregulation**: The gene's involvement in regulating the immune response makes it a potential target for the treatment of immune system dysregulation disorders, such as autoimmune diseases. 3. **Cancer**: The ATP6V0A1 gene's role in regulating protein degradation and sorting makes it a potential target for the treatment of cancer. 4. **Neurodegenerative diseases**: The gene's involvement in regulating signal transduction pathways makes it a potential target for the treatment of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. In conclusion, the ATP6V0A1 gene plays a crucial role in regulating various cellular processes, including endosomal and lysosomal acidification, immune response, and signal transduction. Its involvement in neurological disorders, immune system dysregulation, cancer, and neurodegenerative diseases makes it a potential target for therapeutic interventions. Further research is needed to fully elucidate the function and clinical significance of this gene.

Genular Protein ID: 1361359308

Symbol: VPP1_HUMAN

Name: V-type proton ATPase 116 kDa subunit a 1

UniProtKB Accession Codes:

Q93050 B7Z3B7 Q8N5G7 Q9NSX0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 8 EMDB 5 Ensembl 4 ExpressionAtlas 1 GO 27 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 1 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 5 RefSeq 3 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12643545

Title: Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.

PubMed ID: 12643545

DOI: 10.1021/pr025562r

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28024296

Title: mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide.

PubMed ID: 28024296

DOI: 10.1038/nature21034

PubMed ID: 33065002

Title: Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.

PubMed ID: 33065002

DOI: 10.1016/j.molcel.2020.09.029

PubMed ID: 34909687

Title: Variants in ATP6V0A1 cause progressive myoclonus epilepsy and developmental and epileptic encephalopathy.

PubMed ID: 34909687

DOI: 10.1093/braincomms/fcab245

PubMed ID: 33833240

Title: ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H+-ATPases is essential for brain development in humans and mice.

PubMed ID: 33833240

DOI: 10.1038/s41467-021-22389-5

Sequence Information:

  • Length: 837
  • Mass: 96413
  • Checksum: 80E4842CF6ADEE44
  • Sequence:
    • MGELFRSEEM TLAQLFLQSE AAYCCVSELG ELGKVQFRDL NPDVNVFQRK FVNEVRRCEE 
MDRKLRFVEK EIRKANIPIM DTGENPEVPF PRDMIDLEAN FEKIENELKE INTNQEALKR 
NFLELTELKF ILRKTQQFFD EMADPDLLEE SSSLLEPSEM GRGTPLRLGF VAGVINRERI 
PTFERMLWRV CRGNVFLRQA EIENPLEDPV TGDYVHKSVF IIFFQGDQLK NRVKKICEGF 
RASLYPCPET PQERKEMASG VNTRIDDLQM VLNQTEDHRQ RVLQAAAKNI RVWFIKVRKM 
KAIYHTLNLC NIDVTQKCLI AEVWCPVTDL DSIQFALRRG TEHSGSTVPS ILNRMQTNQT 
PPTYNKTNKF TYGFQNIVDA YGIGTYREIN PAPYTIITFP FLFAVMFGDF GHGILMTLFA 
VWMVLRESRI LSQKNENEMF STVFSGRYII LLMGVFSMYT GLIYNDCFSK SLNIFGSSWS 
VRPMFTYNWT EETLRGNPVL QLNPALPGVF GGPYPFGIDP IWNIATNKLT FLNSFKMKMS 
VILGIIHMLF GVSLSLFNHI YFKKPLNIYF GFIPEIIFMT SLFGYLVILI FYKWTAYDAH 
TSENAPSLLI HFINMFLFSY PESGYSMLYS GQKGIQCFLV VVALLCVPWM LLFKPLVLRR 
QYLRRKHLGT LNFGGIRVGN GPTEEDAEII QHDQLSTHSE DADEPSEDEV FDFGDTMVHQ 
AIHTIEYCLG CISNTASYLR LWALSLAHAQ LSEVLWTMVI HIGLSVKSLA GGLVLFFFFT 
AFATLTVAIL LIMEGLSAFL HALRLHWVEF QNKFYSGTGF KFLPFSFEHI REGKFEE

Genular Protein ID: 3091214484

Symbol: Q53X12_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53X12

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 8 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 3 RuleBase 1 SAM 1

Sequence Information:

  • Length: 831
  • Mass: 95751
  • Checksum: A3D85B27CA2AC55E
  • Sequence:
    • MGELFRSEEM TLAQLFLQSE AAYCCVSELG ELGKVQFRDL NPDVNVFQRK FVNEVRRCEE 
MDRKLRFVEK EIRKANIPIM DTGENPEVPF PRDMIDLEAN FEKIENELKE INTNQEALKR 
NFLELTELKF ILRKTQQFFD EMADPDLLEE SSSLLEPSEM GRGTPLRLGF VAGVINRERI 
PTFERMLWRV CRGNVFLRQA EIENPLEDPV TGDYVHKSVF IIFFQGDQLK NRVKKICEGF 
RASLYPCPET PQERKEMASG VNTRIDDLQM VLNQTEDHRQ RVLQAAAKNI RVWFIKVRKM 
KAIYHTLNLC NIDVTQKCLI AEVWCPVTDL DSIQFALRRG TEHSGSTVPS ILNRMQTNQT 
PPTYNKTNKF TYGFQNIVDA YGIGTYREIN PAPYTIITFP FLFAVMFGDF GHGILMTLFA 
VWMVLRESRI LSQKNENEMF STVFSGRYII LLMGVFSMYT GLIYNDCFSK SLNIFGSSWS 
VRPMFTYNWT EETLRGNPVL QLNPALPGVF GGPYPFGIDP IWNIATNKLT FLNSFKMKMS 
VILGIIHMLF GVSLSLFNHI YFKKPLNIYF GFIPEIIFMT SLFGYLVILI FYKWTAYDAH 
TSENAPSLLI HFINMFLFSY PESGYSMLYS GQKGIQCFLV VVALLCVPWM LLFKPLVLRR 
QYLRRKHLGT LNFGGIRVGN GPTEEDAEII QHDQLSTHSE DADEFDFGDT MVHQAIHTIE 
YCLGCISNTA SYLRLWALSL AHAHVSEVLW TMVIHIGLSV KSLAGGLVLF FFFTAFATLT 
VAILLIMEGL SAFLHALRLH WVEFQNKFYS GTGFKFLPFS FEHIREGKFE E

Genular Protein ID: 3909198861

Symbol: Q53ET5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53ET5

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 8 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 831
  • Mass: 95804
  • Checksum: 0C84BE64B8CC0D03
  • Sequence:
    • MGELFRSEEM TLAQLFLQSE AAYCCVSELG ELGKVQFRDL NPYVNVFQRK FVNEVRRCEE 
MDRKLRFVEK EIRKANIPIM DTGENPEVPF PRDMIDLEAN FEKIENELKE INTNQEALKR 
NFLELTELKF ILRKTQQFFD EMADPDLLEE SSSLLEPSEM GRGTPLRLGF VAGVINRERI 
PTFERMLWRV CRGNVFLRQA EIENPLEDPV TGDYVHKSVF IIFFQGDQLK NRVKKICEGF 
RASLYPCPET PQERKEMASG VNTRIDDLQM VLNQTEDHRQ RVLQAAAKNI RVWFIKVRKM 
KAIYHTLNLC NIDVTQKCLI AEVWCPVTDL DSIQFALRRG TEHSGSTVPS ILNRMQTNQT 
PPTYNKTNKF TYGFQNIVDA YGIGTYREIN PAPYTIITFP FLFAVMFGDF GHGILMTLFA 
VWMVLRESRI LSQKNENEMF STVFSGRYII LLMGVFSMYT GLIYNDCFSK SLNIFGSSWS 
VRPMFTYNWT EETLRGNPVL QLNPALPGVF GGPYPFGIDP IWNIATNKLT FLNSFKMKMS 
VILGIIHMLF GVSLSLFNHI YFKKPLNIYF GFIPEIIFMT SLFGYLVILI FYKWTAYDAH 
TSENAPSLLI HFINMFLFSY PESGYSMLYS GQKGIQCFLV VVALLCVPWM LLFKPLVLRR 
QYLRRKHLGT LNFGGIRVGN GPTEEDAEII QHDQLSTHSE DADEFDFGDT MVHQAIHTIE 
YCLGCISNTA SYLRLWALSL AHAQLSEVLW TMVIHIGLSV KSLAGGLVLF FFFTAFATLT 
VAILLIMEGL SAFLHALRLH WVEFQNKFYS GTGFKFLPFS FEHIREGKFE E

Genular Protein ID: 2554519332

Symbol: Q5CZH6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5CZH6

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 8 IntAct 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1

Sequence Information:

  • Length: 838
  • Mass: 96603
  • Checksum: 20E56A8DA482FDB7
  • Sequence:
    • MGELFRSEEM TLAQLFLQSE AAYCCVSELG ELGKVQFRDL NPDVNVFQRK FVNEVRRCEE 
MDRKLRFVEK EIRKANIPIM DTGENPEVPF PRDMIDLEAN FEKIENELKE INTNQEALKR 
NFLELTELKF ILRKTQQFFD EAELHHQQMA DPDLLEESSS LLEPSEMGRG TPLRLGFVAG 
VINRERIPTF ERMLWRVCRG NVFLRQAEIE NPLEDPVTGD YVHKSVFIIF FQGDQLKNRV 
KKICEGFRAS LYPCPETPQE RKEMASGVST RIDDLQMVLN QMEDHRQRVL QAAAKNIRVW 
FIKVRKMKAI YHTLNLCNID VTQKCLIAEV WCPVTDLDSI QFALRRGTEH SGSTVPSILN 
RMQTNQTPPT YNKTNKFTYG FQNIVDAYGI GTYREINPAP YTIITFPFLF AVMFGDFGHG 
ILMTLFAVWM VLRESRILSQ KNENEMFSTV FSGRYIILLM GVFSMYTGLI YNDCFSKSLN 
IFGSSWSVRP MFTYNWTEET LRGNPVLQLN PALPGVFGGP YPFGIDPIWN IATNKLTFLN 
SFKMKMSVIL GIIHMLFGVS LSLFNHIYFK KPLNIYFGFI PEIIFMTSLF GYLVILIFYK 
WTAYDAHTSE NAPSLLIHFI NMFLFSYPES GYSMLYSGQK GIQCFLVVVA LLCVPWMLLF 
KPLVLRRQYL RRKHLGTLNF GGIRVGNGPT EEDAEIIQHD QLSTHSEDAD EFDFGDTMVH 
QAIHTIEYCL GCISNTASYL RLWALSLAHA QLSEVLWTMV IHIGLSVKSL AGGLVLFFFF 
TAFATLTVAI LLIMEGLSAF LHALRLHWVE FQNKFYSGTG FKFLPFSFEH IREGKFEE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.