Details for: Tslp

Gene ID: 53603

Symbol: Tslp

Ensembl ID: ENSMUSG00000024379

Description: thymic stromal lymphopoietin

Associated with

  • Cytokine signaling in immune system
    (R-MMU-1280215)
  • Immune system
    (R-MMU-168256)
  • Interleukin-7 signaling
    (R-MMU-1266695)
  • Signaling by interleukins
    (R-MMU-449147)
  • Antimicrobial humoral immune response mediated by antimicrobial peptide
    (GO:0061844)
  • Cytokine activity
    (GO:0005125)
  • Defense response to fungus
    (GO:0050832)
  • Defense response to gram-negative bacterium
    (GO:0050829)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Interleukin-7 receptor binding
    (GO:0005139)
  • Interleukin-7-mediated signaling pathway
    (GO:0038111)
  • Negative regulation of apoptotic process
    (GO:0043066)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of chemokine (c-c motif) ligand 1 production
    (GO:0071654)
  • Positive regulation of chemokine production
    (GO:0032722)
  • Positive regulation of cytokine-mediated signaling pathway
    (GO:0001961)
  • Positive regulation of granulocyte colony-stimulating factor production
    (GO:0071657)
  • Positive regulation of inflammatory response
    (GO:0050729)
  • Positive regulation of interleukin-5 production
    (GO:0032754)
  • Positive regulation of interleukin-6 production
    (GO:0032755)
  • Positive regulation of interleukin-10 production
    (GO:0032733)
  • Positive regulation of interleukin-13 production
    (GO:0032736)
  • Positive regulation of mast cell activation
    (GO:0033005)
  • Positive regulation of receptor signaling pathway via stat
    (GO:1904894)
  • Protein binding
    (GO:0005515)
  • Signal transduction
    (GO:0007165)

Other Information

Genular Protein ID: 383779656

Symbol: TSLP_MOUSE

Name: Thymic stromal lymphopoietin

UniProtKB Accession Codes:

Q9JIE6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 DIP 1 DNASU 1 EMBL 2 Ensembl 1 EvolutionaryTrace 1 GO 13 Gene3D 1 GeneTree 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 1 RefSeq 1 SMR 1 STRING 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10974033

Title: Molecular cloning and biological characterization of a novel murine lymphoid growth factor.

PubMed ID: 10974033

DOI: 10.1084/jem.192.5.671

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 24632570

Title: Structural basis of the proinflammatory signaling complex mediated by TSLP.

PubMed ID: 24632570

DOI: 10.1038/nsmb.2794

Sequence Information:

  • Length: 140
  • Mass: 16152
  • Checksum: 5B6D3196E73BAA8B
  • Sequence:
    • MVLLRSLFIL QVLVRMGLTY NFSNCNFTSI TKIYCNIIFH DLTGDLKGAK FEQIEDCESK 
PACLLKIEYY TLNPIPGCPS LPDKTFARRT REALNDHCPG YPETERNDGT QEMAQEVQNI 
CLNQTSQILR LWYSFMQSPE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.