Details for: Nono

Gene ID: 53610

Symbol: Nono

Ensembl ID: ENSMUSG00000031311

Description: non-POU-domain-containing, octamer binding protein

Associated with

Other Information

Genular Protein ID: 3622473033

Symbol: NONO_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q99K48 Q63887 Q9CYQ4 Q9DBP2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 ELM 1 EMBL 6 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 26 Gene3D 2 GeneTree 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MGI 1 MINT 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRO 1 PROSITE 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 8355702

Title: NonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdiss.

PubMed ID: 8355702

DOI: 10.1128/mcb.13.9.5593-5603.1993

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8626664

Title: The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA-binding protein p54nrb.

PubMed ID: 8626664

DOI: 10.1074/jbc.271.19.11177

PubMed ID: 9001221

Title: The intracisternal A-particle proximal enhancer-binding protein activates transcription and is identical to the RNA- and DNA-binding protein p54nrb/NonO.

PubMed ID: 9001221

DOI: 10.1128/mcb.17.2.677

PubMed ID: 12522145

Title: Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.

PubMed ID: 12522145

DOI: 10.1074/jbc.m212632200

PubMed ID: 15140795

Title: Expression and functional significance of mouse paraspeckle protein 1 on spermatogenesis.

PubMed ID: 15140795

DOI: 10.1095/biolreprod.104.028159

PubMed ID: 15860628

Title: PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator.

PubMed ID: 15860628

DOI: 10.1126/science.1107373

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22966205

Title: Distinct roles of DBHS family members in the circadian transcriptional feedback loop.

PubMed ID: 22966205

DOI: 10.1128/mcb.00334-12

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 32286661

Title: Nono deficiency compromises TET1 chromatin association and impedes neuronal differentiation of mouse embryonic stem cells.

PubMed ID: 32286661

DOI: 10.1093/nar/gkaa213

PubMed ID: 26571461

Title: Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects.

PubMed ID: 26571461

DOI: 10.1038/nn.4169

Sequence Information:

  • Length: 473
  • Mass: 54541
  • Checksum: F65E6AE25D471A38
  • Sequence:
    • MQSNKAFNLE KQNHTPRKHH QHHHQQHHQQ QQQQQQQQPP PPIPANGQQA SSQNEGLTID 
LKNFRKPGEK TFTQRSRLFV GNLPPDITEE EMRKLFEKYG KAGEVFIHKD KGFGFIRLET 
RTLAEIAKVE LDNMPLRGKQ LRVRFACHSA SLTVRNLPQY VSNELLEEAF SVFGQVERAV 
VIVDDRGRPS GKGIVEFSGK PAARKALDRC SEGSFLLTTF PRPVTVEPMD QLDDEEGLPE 
KLVIKNQQFH KEREQPPRFA QPGSFEYEYA MRWKALIEME KQQQDQVDRN IKEAREKLEM 
EMEAARHEHQ VMLMRQDLMR RQEELRRMEE LHNQEVQKRK QLELRQEEER RRREEEMRRQ 
QEEMMRRQQE GFKGTFPDAR EQEIRMGQMA MGGAMGINNR GAMPPAPVPP GTPAPPGPAT 
MMPDGTLGLT PPTTERFGQA ATMEGIGAIG GTPPAFNRPA PGAEFAPNKR RRY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.