Details for: Porcn

Gene ID: 53627

Symbol: Porcn

Ensembl ID: ENSMUSG00000031169

Description: porcupine O-acyltransferase

Associated with

Other Information

Genular Protein ID: 1953775717

Symbol: PORCN_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9JJJ7 A2AC30 A2AC32 A2AC33 Q9CWT0 Q9JJJ8 Q9JJJ9 Q9JJK0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 CCDS 4 CTD 1 ChEBI 4 ChEMBL 1 DNASU 1 EC 1 EMBL 7 Ensembl 4 ExpressionAtlas 1 GO 15 GeneTree 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 RNAct 1 RefSeq 5 Rhea 3 SMR 1 STRING 1 TreeFam 1 UCSC 5 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10866835

Title: The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family.

PubMed ID: 10866835

DOI: 10.1046/j.1432-1033.2000.01478.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12842094

Title: Misexpression of mouse porcupine isoforms modulates the differentiation of P19 embryonic carcinoma cells.

PubMed ID: 12842094

DOI: 10.1016/s1065-6995(03)00080-5

PubMed ID: 17141155

Title: Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion.

PubMed ID: 17141155

DOI: 10.1016/j.devcel.2006.10.003

PubMed ID: 22046319

Title: Differential palmit(e)oylation of Wnt1 on C93 and S224 residues has overlapping and distinct consequences.

PubMed ID: 22046319

DOI: 10.1371/journal.pone.0026636

PubMed ID: 24055053

Title: Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins.

PubMed ID: 24055053

DOI: 10.1016/j.celrep.2013.08.027

PubMed ID: 24798332

Title: Identification of key residues and regions important for porcupine-mediated Wnt acylation.

PubMed ID: 24798332

DOI: 10.1074/jbc.m114.561209

Sequence Information:

  • Length: 461
  • Mass: 52508
  • Checksum: 25A52681C251A0A6
  • Sequence:
    • MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG 
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW 
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV 
QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR 
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE 
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV 
EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAIFHL SYLGSLFDVD 
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.