IL20RB | ENSG00000174564 | NCBI 53833

Details for: IL20RB

Gene ID: 53833

Symbol: IL20RB

Ensembl ID: ENSG00000174564

Description: interleukin 20 receptor subunit beta

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Immune system
(R-HSA-168256)
Interleukin-20 family signaling
(R-HSA-8854691)
Signaling by interleukins
(R-HSA-449147)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine receptor activity
(GO:0004896)
Homeostasis of number of cells within a tissue
(GO:0048873)
Immune response-inhibiting signal transduction
(GO:0002765)
Inflammatory response to antigenic stimulus
(GO:0002437)
Interleukin-20 binding
(GO:0042015)
Negative regulation of interleukin-2 production
(GO:0032703)
Negative regulation of t cell proliferation
(GO:0042130)
Negative regulation of type ii interferon production
(GO:0032689)
Negative regulation of type iv hypersensitivity
(GO:0001808)
Plasma membrane
(GO:0005886)
Positive regulation of interleukin-4 production
(GO:0032753)
Positive regulation of interleukin-10 production
(GO:0032733)
Protein binding
(GO:0005515)
T cell homeostasis
(GO:0043029)
T cell proliferation
(GO:0042098)

Other Information

Proteins

Interleukin-20 receptor subunit beta

Genular Protein ID: 3087761525

Symbol: I20RB_HUMAN

Name: Interleukin-20 receptor subunit beta

UniProtKB Accession Codes:

Q6UXL0 B4DL40 Q6P438 Q8IYY5 Q8TAJ7

Database IDs:

Citations:

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 11163236

Title: Interleukin 20: discovery, receptor identification, and role in epidermal function.

PubMed ID: 11163236

DOI: 10.1016/s0092-8674(01)00187-8

PubMed ID: 11564763

Title: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types.

PubMed ID: 11564763

DOI: 10.4049/jimmunol.167.7.3545

PubMed ID: 12351624

Title: Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions.

PubMed ID: 12351624

DOI: 10.1074/jbc.m205114200

PubMed ID: 14580208

Title: Characterization of the recombinant extracellular domains of human interleukin-20 receptors and their complexes with interleukin-19 and interleukin-20.

PubMed ID: 14580208

DOI: 10.1021/bi0354583

PubMed ID: 22802649

Title: Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines.

PubMed ID: 22802649

DOI: 10.1073/pnas.1117551109

Sequence Information:

Length: 311
Mass: 35076
Checksum: FF366D518116D9E3
Sequence:

MQTFTMVLEE IWTSLFMWFF YALIPCLLTD EVAILPAPQN LSVLSTNMKH LLMWSPVIAP 
GETVYYSVEY QGEYESLYTS HIWIPSSWCS LTEGPECDVT DDITATVPYN LRVRATLGSQ 
TSAWSILKHP FNRNSTILTR PGMEITKDGF HLVIELEDLG PQFEFLVAYW RREPGAEEHV 
KMVRSGGIPV HLETMEPGAA YCVKAQTFVK AIGRYSAFSQ TECVEVQGEA IPLVLALFAF 
VGFMLILVVV PLFVWKMGRL LQYSCCPVVV LPDTLKITNS PQKLISCRRE EVDACATAVM 
SPEELLRAWI S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: IL20RB

Associated with

Other Information

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence, annotation and analysis of human chromosome 3. PubMed ID: 16641997

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Signal peptide prediction based on analysis of experimentally verified cleavage sites. PubMed ID: 15340161

Interleukin 20: discovery, receptor identification, and role in epidermal function. PubMed ID: 11163236

STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types. PubMed ID: 11564763

Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions. PubMed ID: 12351624

Characterization of the recombinant extracellular domains of human interleukin-20 receptors and their complexes with interleukin-19 and interleukin-20. PubMed ID: 14580208

Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines. PubMed ID: 22802649