Map3k14 | ENSMUSG00000020941 | NCBI 53859

Details for: Map3k14

Gene ID: 53859

Symbol: Map3k14

Ensembl ID: ENSMUSG00000020941

Description: mitogen-activated protein kinase kinase kinase 14

Associated with

Adaptive immune system
(R-MMU-1280218)
C-type lectin receptors (clrs)
(R-MMU-5621481)
Cd28 co-stimulation
(R-MMU-389356)
Cd28 dependent pi3k/akt signaling
(R-MMU-389357)
Clec7a (dectin-1) signaling
(R-MMU-5607764)
Costimulation by the cd28 family
(R-MMU-388841)
Cytokine signaling in immune system
(R-MMU-1280215)
Dectin-1 mediated noncanonical nf-kb signaling
(R-MMU-5607761)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Nik-->noncanonical nf-kb signaling
(R-MMU-5676590)
Tnfr2 non-canonical nf-kb pathway
(R-MMU-5668541)
Tnf receptor superfamily (tnfsf) members mediating non-canonical nf-kb pathway
(R-MMU-5676594)
Atp binding
(GO:0005524)
Canonical nf-kappab signal transduction
(GO:0007249)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Defense response to virus
(GO:0051607)
Fibrillar center
(GO:0001650)
Immune response
(GO:0006955)
Intracellular membrane-bounded organelle
(GO:0043231)
Kinase activity
(GO:0016301)
Map kinase kinase kinase activity
(GO:0004709)
Non-canonical nf-kappab signal transduction
(GO:0038061)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Phosphorylation
(GO:0016310)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine kinase activity
(GO:0004674)
Transferase activity
(GO:0016740)

Other Information

Proteins

M3K14_MOUSE

Genular Protein ID: 539241694

Symbol: M3K14_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9WUL6

Database IDs:

Citations:

PubMed ID: 10319865

Title: Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase.

PubMed ID: 10319865

DOI: 10.1038/8780

PubMed ID: 11239468

Title: NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100.

PubMed ID: 11239468

DOI: 10.1016/s1097-2765(01)00187-3

PubMed ID: 26029823

Title: Catalytic subunits of the phosphatase calcineurin interact with NF-kappaB-inducing kinase (NIK) and attenuate NIK-dependent gene expression.

PubMed ID: 26029823

DOI: 10.1038/srep10758

Sequence Information:

Length: 942
Mass: 103080
Checksum: 3BE4E4BA2D25C200
Sequence:

MAVMEVACPG TPGSAVGQQK ELAKAKEKTQ SLGKKQSCIF KLEAVEKSPV FCGKWEILND 
VITKGTAKDG SEGGPPAISI IAQAECENSQ EFSPTFSERI FIAGSQQYSQ SESLDQIPNN 
VAHATEGKMA RVCRRGKRHG KARKKRRKKR SKSLAQAGVA LAKPLPRTPE QESCTIPVQE 
DESPLGNLYA RNVSQFTKPL GGPGLGHLCF KKQDEGLRPV LPRPELHKLI SPLQCLNHVW 
KLHHPQATGP RPHPTHPFPY SGMPHPFPFY PLEPWKPYML DSAVLDKLAG VSGQRPLPGP 
PHLSQLAHGD SQKPLPGPHL ESSCPSRGAL EKVPVEEYLV HALQGSVSSG QAHSLASLAK 
TWSSGSAKLQ RLGPETEDNE GVLLTEKLKP VDYEYREEVH WMTHQPRVGR GSFGEVHRMK 
DKQTGFQCAV KKVRLEVFRV EELVACAGLS SPRIVPLYGA VREGPWVNIF MELLEGGSLG 
QLIKQMGCLP EDRALYYLGQ ALEGLEYLHT RRILHGDVKA DNVLLSSDGS RAALCDFGHA 
LCLQPDGLGK SLLTGDYIPG TETHMAPEVV MGKPCDAKVD IWSSCCMMLH MLNGCHPWTQ 
YFRGPLCLKI ASEPPPIREI PPSCAPLTAQ AIQEGLRKEP VHRASAMELR RKVGKALQEV 
GGLKSPWKGE YKEPRPPPQD QATCHQTLPT PPRENPPAKA NTDGAPEPQP PLPPEPPEPS 
KAPALNLSKE ESGTWEPLPL SSLDPATAKG PSFPDRRATL PELELQQLEI ELFLNSLSQP 
FSLEEQEQIL SCLSIDSLSL SDDSEKNPSK ASQSSRDTLS SGVHSWNSQA EARTCSCSTA 
LARGRPTDIP SYFNGVKVQI QSLNGEHLHI REFHRVKVGD IATGISSQIP ATAFSLVTKD 
GQPVCYDMEV PDSGIDLQCT LAPDGSFAWT WRVKHGQLEN RP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.