Slc5a3 | ENSMUSG00000089774 | NCBI 53881

Details for: Slc5a3

Gene ID: 53881

Symbol: Slc5a3

Ensembl ID: ENSMUSG00000089774

Description: solute carrier family 5 (inositol transporters), member 3

Associated with

Inositol transporters
(R-MMU-429593)
Slc-mediated transmembrane transport
(R-MMU-425407)
Transport of bile salts and organic acids, metal ions and amine compounds
(R-MMU-425366)
Transport of small molecules
(R-MMU-382551)
Apical plasma membrane
(GO:0016324)
Basolateral plasma membrane
(GO:0016323)
Glucose:sodium symporter activity
(GO:0005412)
Inositol metabolic process
(GO:0006020)
Membrane
(GO:0016020)
Monoatomic ion transport
(GO:0006811)
Myo-inositol:sodium symporter activity
(GO:0005367)
Myo-inositol transport
(GO:0015798)
Perinuclear region of cytoplasm
(GO:0048471)
Peripheral nervous system development
(GO:0007422)
Plasma membrane
(GO:0005886)
Positive regulation of catalytic activity
(GO:0043085)
Positive regulation of protein localization to membrane
(GO:1905477)
Positive regulation of reactive oxygen species biosynthetic process
(GO:1903428)
Potassium channel regulator activity
(GO:0015459)
Protein binding
(GO:0005515)
Regulation of respiratory gaseous exchange
(GO:0043576)
Regulation of transporter activity
(GO:0032409)
Sodium ion transport
(GO:0006814)
Symporter activity
(GO:0015293)
Transmembrane transport
(GO:0055085)
Transmembrane transporter activity
(GO:0022857)
Transmembrane transporter binding
(GO:0044325)
Voltage-gated potassium channel complex
(GO:0008076)

Other Information

Proteins

Sodium/myo-inositol cotransporter
Q3UMR9_MOUSE

Genular Protein ID: 4225936798

Symbol: SC5A3_MOUSE

Name: Sodium/myo-inositol cotransporter

UniProtKB Accession Codes:

Q9JKZ2 B2RU60

Database IDs:

Citations:

PubMed ID: 10773690

Title: Murine chromosome 16 telomeric region, homologous with human chromosome 21q22, contains the osmoregulatory Na(+)/myo-inositol cotransporter (SLC5A3) gene.

PubMed ID: 10773690

DOI: 10.1159/000015509

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12582158

Title: Loss of murine Na+/myo-inositol cotransporter leads to brain myo-inositol depletion and central apnea.

PubMed ID: 12582158

DOI: 10.1074/jbc.m213176200

PubMed ID: 12719585

Title: Sodium-dependent myo-inositol transporter 1 is a cellular receptor for Mus cervicolor M813 murine leukemia virus.

PubMed ID: 12719585

DOI: 10.1128/jvi.77.10.5926-5932.2003

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24595108

Title: KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability.

PubMed ID: 24595108

DOI: 10.1126/scisignal.2005025

Sequence Information:

Length: 718
Mass: 79583
Checksum: D0371D6ECF08503B
Sequence:

MRAVLEAADI AVVALYFILV MCIGFFAMWK SNRSTVSGYF LAGRSMTWVA IGASLFVSNI 
GSEHFIGLAG SGAASGFAVG AWEFNALLLL QLLGWVFIPI YIRSGVYTMP EYLSKRFGGH 
RIQVYFAALS LLLYIFTKLS VDLYSGALFI QESLGWNLYV SVILLIGMTA LLTVTGGLVA 
VIYTDTLQAL LMIIGALTLM VISMVKIGGF EEVKRRYMLA SPDVASILLK YNLSNTNACM 
VHPKANALKM LRDPTDEDVP WPGFILGQTP ASVWYWCADQ VIVQRVLAAK NIAHAKGSTL 
MAGFLKLLPM FIIVVPGMIS RIVFADEIAC INPEHCMQVC GSRAGCSNIA YPRLVMTLVP 
VGLRGLMMAV MIAALMSDLD SIFNSASTIF TLDVYKLIRK SASSRELMIV GRIFVAFMVV 
ISIAWVPIIV EMQGGQMYLY IQEVADYLTP PVAALFLLAI FWKRCNEQGA FYGGMAGFVL 
GAVRLILAFT YRAPECDQPD NRPGFIKDIH YMYVATALFW ITGLITVIVS LLTPPPTKDQ 
IRTTTFWSKK TLVTKESCSQ KDEPYKMQEK SILQCSENSE VISHTIPNGK SEDSIKGLQP 
EDVNLLVTCR EEGNPVASMG HSEAETPVDA YSNGQAALMG EREREKETEN RSRYWKFIDW 
FCGFKSKSLS KRSLRDLMDE EAVCLQMLEE TPQVKVILNI GLFAVCSLGI FMFVYFSL

Genular Protein ID: 2684577781

Symbol: Q3UMR9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UMR9

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 532
Mass: 58456
Checksum: BAA1F8311948773E
Sequence:

MRAVLEAADI AVVALYFILV MCIGFFAMWK SNRSTVSGYF LAGRSMTWVA IGASLFVSNI 
GSEHFIGLAG SGAASGFAVG AWEFNALLLL QLLGWVFIPI YIRSGVYTMP EYLSKRFGGH 
RIQVYFAALS LLLYIFTKLS VDLYSGALFI QESLGWNLYV SVILLIGMTA LLTVTGGLVA 
VIYTDTLQAL LMIIGALTLM VISMVKIGGF EEVKRRYMLA SPDVASILLK YNLSNTNACM 
VHPKANALKM LRDPTDEDVP WPGFILGQTP ASVWYWCADQ VIVQRVLAAK NIAHAKGSTL 
MAGFLKLLPM FIIVVPGMIS RIVFADEIAC INPEHCMQVC GSRAGCSNIA YPRLVMTLVP 
VGLRGLMMAV MIAALMSDLD SIFNSASTIF TLDVYKLIRK SASSRELMIV GRIFVAFMVV 
ISIAWVPIIV EMQGGQMYLY IQEVADYLTP PVAALFLLAI FWKRCNEQGA FYGGMAGFVL 
GAVRLILAFT YRAPECDQPD NRPGFIKDIH YMYVATALFW ITGLITVIVS LL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc5a3

Associated with

Other Information

Murine chromosome 16 telomeric region, homologous with human chromosome 21q22, contains the osmoregulatory Na(+)/myo-inositol cotransporter (SLC5A3) gene. PubMed ID: 10773690

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Loss of murine Na+/myo-inositol cotransporter leads to brain myo-inositol depletion and central apnea. PubMed ID: 12582158

Sodium-dependent myo-inositol transporter 1 is a cellular receptor for Mus cervicolor M813 murine leukemia virus. PubMed ID: 12719585

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability. PubMed ID: 24595108

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073