Slc7a10 | ENSMUSG00000030495 | NCBI 53896

Details for: Slc7a10

Gene ID: 53896

Symbol: Slc7a10

Ensembl ID: ENSMUSG00000030495

Description: solute carrier family 7 (cationic amino acid transporter, y+ system), member 10

Associated with

Amino acid transport across the plasma membrane
(R-MMU-352230)
Basigin interactions
(R-MMU-210991)
Cell surface interactions at the vascular wall
(R-MMU-202733)
Hemostasis
(R-MMU-109582)
Slc-mediated transmembrane transport
(R-MMU-425407)
Transport of inorganic cations/anions and amino acids/oligopeptides
(R-MMU-425393)
Transport of small molecules
(R-MMU-382551)
Amino acid transmembrane transport
(GO:0003333)
Amino acid transport
(GO:0006865)
Apical dendrite
(GO:0097440)
D-alanine transport
(GO:0042941)
D-serine transport
(GO:0042942)
Glycine transport
(GO:0015816)
L-amino acid transmembrane transporter activity
(GO:0015179)
Membrane
(GO:0016020)
Negative regulation of brown fat cell differentiation
(GO:1903444)
Neuronal cell body
(GO:0043025)
Neutral amino acid transport
(GO:0015804)
Neutral l-amino acid transmembrane transporter activity
(GO:0015175)
Plasma membrane
(GO:0005886)
Positive regulation of synaptic transmission, glycinergic
(GO:0060094)
Protein binding
(GO:0005515)
Transmembrane transport
(GO:0055085)
Transmembrane transporter activity
(GO:0022857)

Other Information

Proteins

Asc-type amino acid transporter 1

Genular Protein ID: 378815610

Symbol: AAA1_MOUSE

Name: Asc-type amino acid transporter 1

UniProtKB Accession Codes:

P63115 Q9CW25 Q9JMH8

Database IDs:

Citations:

PubMed ID: 10734121

Title: Identification and characterization of a Na+-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L- amino acids.

PubMed ID: 10734121

DOI: 10.1074/jbc.275.13.9690

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 25755256

Title: The alanine-serine-cysteine-1 (Asc-1) transporter controls glycine levels in the brain and is required for glycinergic inhibitory transmission.

PubMed ID: 25755256

DOI: 10.15252/embr.201439561

PubMed ID: 27759100

Title: The astrocytic transporter SLC7A10 (Asc-1) mediates glycinergic inhibition of spinal cord motor neurons.

PubMed ID: 27759100

DOI: 10.1038/srep35592

PubMed ID: 34749773

Title: Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain.

PubMed ID: 34749773

DOI: 10.1186/s13041-021-00874-8

PubMed ID: 33707431

Title: Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population.

PubMed ID: 33707431

DOI: 10.1038/s41467-021-21826-9

Sequence Information:

Length: 530
Mass: 57549
Checksum: 0C5A80BF922DB54D
Sequence:

MRRDSDMASH IQQPGGHGNP GPAPSPSPGP GPGPGASERV ALKKEIGLVS ACTIIIGNII 
GSGIFISPKG VLEHSGSVGL ALFVWVLGGG VTALGSLCYA ELGVAIPKSG GDYAYVTEIF 
GGLAGFLLLW SAVLIMYPTS LAVISMTFSN YVLQPVFPNC IPPATASRVL SMACLMLLTW 
VNSSSVRWAT RIQVIFTGGK LLALSLIITV GFVQIFQGHF EELRPTNAFA FWMTPSVGHL 
ALAFLQGSFA FSGWNFLNYV TEELVDPRKN LPRAIFISIP LVTFVYTFTN VAYFTAMSPQ 
ELLSSNAVAV TFGEKLLGYF SWVMPVSVAL STFGGINGYL FTSSRLCFSG AREGHLPSFL 
AMIHVRRCTP IPALLVCCGA TAVIMLVGDT YTLINYVSFI NYLCYGVTIL GLLVLRWRRP 
ALHRPIKVNL LVPVVYLVFW AFLLVFSFIS EPMVCGVGII IILTGVPIFF LGVFWRSKPK 
CVHRFTESMT RWGQELCFVV YPQGSLEEEE NGPMGQPSPL PITDKPLKTQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc7a10

Associated with

Other Information

Identification and characterization of a Na+-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L- amino acids. PubMed ID: 10734121

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The alanine-serine-cysteine-1 (Asc-1) transporter controls glycine levels in the brain and is required for glycinergic inhibitory transmission. PubMed ID: 25755256

The astrocytic transporter SLC7A10 (Asc-1) mediates glycinergic inhibition of spinal cord motor neurons. PubMed ID: 27759100

Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain. PubMed ID: 34749773

Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population. PubMed ID: 33707431