Details for: Rfx5

Gene ID: 53970

Symbol: Rfx5

Ensembl ID: ENSMUSG00000005774

Description: regulatory factor X, 5 (influences HLA class II expression)

Associated with

  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulator complex
    (GO:0090575)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)

Other Information

Genular Protein ID: 3051264553

Symbol: RFX5_MOUSE

Name: DNA-binding protein Rfx5

UniProtKB Accession Codes:

Q9JL61 D3Z1N0 G3X9S6 Q3U180

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 13 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 5 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 10779326

Title: A functionally essential domain of RFX5 mediates activation of major histocompatibility complex class II promoters by promoting cooperative binding between RFX and NF-Y.

PubMed ID: 10779326

DOI: 10.1128/mcb.20.10.3364-3376.2000

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

Sequence Information:

  • Length: 658
  • Mass: 69735
  • Checksum: E1807134D8FC4A19
  • Sequence:
    • MAEDKPDAKS PKTGARPQGG ADAGEPTTLL QRLRGTISKA VQNKVEGILQ EVQKFSDNDK 
LYLYLQLPSG PSVGEKSSEP SLLSNEEYMY AYRWIRNHLE EHMDTCLPKQ SVYDAYRKYC 
ESLACCRPLS TANFGKIIRE IFPDIKARRL GGRGQSKYCY SGIRRKTLVS MPPLPGLDLK 
GSESPEMGPE VSPAPRDELV EAACALTCDW AERILKRSFS SIVQVARYLL QQHLISARSA 
HAHVLKAGGL AEEDERAPRE RSLCKSKNVV ESLEGGGPKK PERPAQPPKE QEARAGTDLP 
GRAERKKSVI DSSVPAASKP QVNALVARLP VLLPRAPRSL ITPISGTLKV ATLPLPTRVG 
GPQTAVPIIN MILPPVPTLS GAGPGPGPGL GPRFGPGPGL GPGPGPGLGA GLGPGLGPGL 
GAGPGPGLGA GLGAGLGLGP GRVPPRAPIL PRGAENREVG ISSDPRPHDK GIKRTAEVPL 
SEASGQDPPV KEMKHETQDT TVSEAKRKRG RPRKKPGGSG ERNATPEKSA AIVNSPRSPR 
LLWETWGSKR ENNFIGRPEG PGPGGEAERE TVLVQGQQDG AVSKGERSLS SQEAKEAEDK 
IPPVTSKVSV IKGRIQKEAL QLVKGEADAA TQGNKGLKGR VLQSSLTPEH KDPKATPP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.